Mikolas was removed from Saturday's start against the Cubs with right forearm tightness, Katie Woo of The Athletic reports.

EDGE Analysis

The 32-year-old surrendered one run over four frames during his first outing since the 2019 playoffs, but he left the contest after the forearm issue cropped up while warming up for the fifth inning. It's obviously a worrying development for Mikolas, who missed the entirety of last season due to surgery on his right flexor tendon. According to Zachary Silver of MLB.com, the right-hander is unsurprisingly undergoing an MRI to help determine the severity of the issue.

Mikolas (shoulder) was activated from the 10-day injured list as expected ahead of his scheduled start Saturday against the Cubs.

EDGE Analysis

Mikolas missed all of last season with a forearm injury and has been out since the start of this year with a shoulder issue. He's looked good in three rehab outings, posting a 3.65 ERA and an 11:2 K:BB in 12.1 innings for Triple-A Memphis. He threw 80 pitches in his most recent rehab start, so he should be able to get close 100 pitches Saturday if all goes well. Seth Elledge was optioned in a corresponding move.

Mikolas (shoulder) is scheduled to come off the 10-day injured list and start Saturday against the Cubs, Derrick Goold of the St. Louis Post-Dispatch reports.

EDGE Analysis

The 32-year-old will see his first MLB action since the 2019 playoffs after sitting out last season with a forearm injury and missing the first seven weeks of 2021 due to a shoulder issue. Mikolas threw 80 pitches in his last rehab start for Triple-A Memphis on Sunday, so he shouldn't face any significant workload limitations in his season debut.

Mikolas (shoulder) worked six scoreless innings for Triple-A Memphis in his most recent rehab outing Sunday. He gave up four hits and a walk with three strikeouts.

EDGE Analysis

Making his third rehab start for Memphis, Mikolas not only worked deeper into Sunday's contest than he had in the previous two outings, but he was also more effective. He pumped in 57 of his 80 pitches for strikes, and that sort of workload suggests he's sufficiently stretched out for starting duty at the big-league level. Expect the Cardinals to reinstate him from the 10-day injured list and have him start one of their three games against the Cubs this upcoming weekend.

Mikolas (shoulder) is scheduled for a rehab start with Triple-A Memphis on Sunday, Jeff Jones of the Belleville News-Democrat reports.

EDGE Analysis

Mikolas made his second rehab appearance Tuesday and allowed three runs on five hits and no walks while striking out five in four innings. He'll presumably attempt to build up more in Sunday's start and could return to the majors as early as the following weekend against the Cubs if everything goes smoothly.

Mikolas (shoulder) is scheduled for a rehab start Wednesday with Triple-A Memphis, Jeff Jones of the Belleville News-Democrat reports.

EDGE Analysis

The 32-year-old struggled in his first rehab start last Wednesday and threw 57 pitches over 2.1 innings, and he'll make another start for Memphis this week. Mikolas is expected to require another rehab outing after Wednesday before rejoining the big-league club, so he's likely about two weeks out from being activated from the injured list.

Mikolas (shoulder) made a rehab start for Triple-A Memphis on Wednesday and took a loss to Durham, allowing two earned runs on five hits and a walk over 2.1 innings. He struck out three.

EDGE Analysis

Mikolas worked up to 57 pitches -- 39 which found the strike zone -- but he also got off on the wrong foot by yielding a solo home run to Rays prospect Vidal Brujan in the first inning. However, the right-hander's ability to tolerate a relatively robust workload in his first taste of competitive game action since 2019 was encouraging, and if his shoulder responds well in the coming days, he could be back in the big leagues within the next few weeks.

Mikolas (shoulder) is expected to begin a minor-league rehab assignment Wednesday with Triple-A Memphis, Jim Hayes of Bally Sports Midwest reports.

EDGE Analysis

The 32-year-old threw two innings at the alternate training site last weekend and will progress to minor-league action when that season begins this week. Mikolas is on track for a return in late May, as he should require a lengthy rehab assignment since he hasn't pitched in the majors since September 2019.

Mikolas (shoulder) threw two innings at the Cardinals' alternate training site Sunday, the Associated Press reports.

EDGE Analysis

The veteran right-hander's progress has been fairly deliberate, yet Sunday's activity level is certainly encouraging. Mikolas likely is still multiple weeks away from making his regular-season debut despite his recent progress, but the fact he's been free of setbacks for multiple weeks at this point is a bright spot.

Mikolas (shoulder) recently faced live hitters for the first time since late February, but he still projects for a late-May season debut at the earliest, Zachary Silver of MLB.com reports.

EDGE Analysis

The right-hander has been limited to fastballs and changeups thus far in his throwing sessions for precautionary reasons, which underscores how much he still realistically has to go to be ready for game action. Manager Mike Shildt currently compares Mikolas to a pitcher who's just starting to ramp up for Grapefruit League starts in late February, and the veteran will look to next incorporate breaking balls into a batting practice session for the first time in his rehabilitation process.