Rousseau sustained a high-ankle sprain during Sunday's 20-17 loss at the Jets and is considered week-to-week, Ian Rapoport of NFL Network reports.

EDGE Analysis

Rousseau missed the second half of Buffalo's loss in Week 9 with the injury, and he's now in jeopardy of missing multiple games as he recovers. The sophomore first-rounder was on pace for a 12-sack season heading into Sunday's game, but until he's ready to return, A.J. Epenesa and Shaq Lawson should see increased reps.

Rousseau is questionable to return to Sunday's game against the Bears with an ankle injury.

EDGE Analysis

Rousseau did not record a tackle in the first half and was listed as questionable coming out of halftime. With the 2021 first-round pick sidelined, expect Carlos Basham and A.J. Epenesa to step up into bigger roles opposite Von Miller on Sunday.

Rousseau posted three tackles (two solo) and 1.5 sacks during Sunday's 21-19 loss to the Dolphins.

EDGE Analysis

Rousseau recorded his lone solo sack late in the second quarter on a second-and-10 play, ultimately forcing a punt. He got after Tua Tagovailoa again in the fourth when he split a sack with defensive back Damar Hamlin. Across three games, the second-year defensive end has totaled 11 tackles and 3.5 sacks and appears to be benefitting from plenty of one-on-one pass-rush opportunities while playing opposite Von Miller.

Rousseau logged four tackles (three solo) including one sack during Monday's 41-7 win over Tennessee.

EDGE Analysis

Rousseau registered four tackles and a sack for the second straight game, even though he played 18 fewer defensive snaps compared to Week 1 (44). Rousseau is currently tied for the Bills' team lead in sacks, and he should continue to receive the benefit of one-on-one pass-rushing looks while playing opposite Von Miller this season.

Rousseau registered four solo tackles, one sack and one pass defense during Thursday's 31-10 win over the Rams.

EDGE Analysis

Rousseau tipped a pass intended for Cooper Kupp at the line in the first quarter and sacked Matthew Stafford on a third-and-short situation in the third quarter. The second-year defensive end played 45 of the team's 67 defensive snaps and will likely be a key piece in Buffalo's defense in 2022. As a rookie, the 2021 first-round pick recorded 50 tackles, four sacks, four pass defenses and one interception across 17 appearances.

Rousseau recorded seven tackles (five solo) in the Bills' 41-15 loss to the Colts on Sunday.

EDGE Analysis

Rousseau continues to make an impact on the defensive line in his rookie year. The Bills' 2021 first-round selection now has 33 tackles, three sacks, a pass defensed and an interception on the season.

Rousseau managed five tackles (four solo), one sack, one pass breakup and one interception during Sunday night's win over the Chiefs.

EDGE Analysis

Rousseau put together the best game of his young career against a fellow AFC powerhouse, bringing him to three sacks on the season. The rookie first-round pick earned AFC Defensive Player of the Week honors for his performance, and he'll get another primetime matchup Week 6 in the form of a Monday night road game in Tennessee.

Rousseau (toe) logged a full practice Thursday.

EDGE Analysis

The rookie popped up on the injury report Wednesday as a non-particpant in practice. There appears to be no concern of him missing Sunday's game versus the Chiefs and he'll look to build upon his 13 tackles and two sacks in the contest.

Rousseau did not practice Wednesday due to a toe injury.

EDGE Analysis

We'll see if the rookie can ramp things up and get himself in position to play this week at Kansas City. The early returns on the first-rounder out of Miami are good so far, as he's worked himself into the rotation on a strong defense while posting 13 tackles and 2.0 sacks.

Rousseau had five tackles and his first two NFL sacks in Sunday's win over the Dolphins.

EDGE Analysis

Rousseau slipped down to the bottom of the first round in April's draft, mostly because he sat out last season for the Miami Hurricanes due to COVID concerns. It looks like the Bills may have gotten themselves a steal, as the 6-foot-6 Rousseau has already worked himself into the rotation on a talented line and is proving himself a handful for opposing linemen. He's probably not quite IDP worthy yet, but if he can keep carving out playing time, that day may not be too far off.