Rousseau (ankle) has been ruled out for Sunday's contest against the Browns, Alaina Getzenberg of ESPN.com reports.

EDGE Analysis

Rousseau will miss a second consecutive game in Week 11 after suffering a high-ankle sprain in Week 9 versus the Jets. The defensive end will now shift his focus to being ready for the Bills' Thanksgiving Day matchup with the Lions on Thursday.

Rousseau missed practice Wednesday due to an ankle injury.

EDGE Analysis

The second-year defensive end has a high-ankle sprain and it may be a bit of a surprise if he's able to return this week against the Browns. Even Week 12 may be a tough task with the Bills set to play Thanksgiving Day.

Rousseau (ankle) has been ruled out for Sunday's game against the Vikings, Maddy Glab of the Bills' official site reports.

EDGE Analysis

Rousseau suffered a high-ankle sprain in a Week 9 matchup with the Jets, missing the second half of that contest. The 22-year-old defensive end has recorded 21 total tackles so far this season, and his five sacks are good for the second-highest total on Buffalo's formidable defense. In Rousseau's absence, A.J. Epenesa and Shaq Lawson should see increased playing time.

Rousseau sustained a high-ankle sprain during Sunday's 20-17 loss at the Jets and is considered week-to-week, Ian Rapoport of NFL Network reports.

EDGE Analysis

Rousseau missed the second half of Buffalo's loss in Week 9 with the injury, and he's now in jeopardy of missing multiple games as he recovers. The sophomore first-rounder was on pace for a 12-sack season heading into Sunday's game, but until he's ready to return, A.J. Epenesa and Shaq Lawson should see increased reps.

Rousseau is questionable to return to Sunday's game against the Bears with an ankle injury.

EDGE Analysis

Rousseau did not record a tackle in the first half and was listed as questionable coming out of halftime. With the 2021 first-round pick sidelined, expect Carlos Basham and A.J. Epenesa to step up into bigger roles opposite Von Miller on Sunday.

Rousseau posted three tackles (two solo) and 1.5 sacks during Sunday's 21-19 loss to the Dolphins.

EDGE Analysis

Rousseau recorded his lone solo sack late in the second quarter on a second-and-10 play, ultimately forcing a punt. He got after Tua Tagovailoa again in the fourth when he split a sack with defensive back Damar Hamlin. Across three games, the second-year defensive end has totaled 11 tackles and 3.5 sacks and appears to be benefitting from plenty of one-on-one pass-rush opportunities while playing opposite Von Miller.

Rousseau logged four tackles (three solo) including one sack during Monday's 41-7 win over Tennessee.

EDGE Analysis

Rousseau registered four tackles and a sack for the second straight game, even though he played 18 fewer defensive snaps compared to Week 1 (44). Rousseau is currently tied for the Bills' team lead in sacks, and he should continue to receive the benefit of one-on-one pass-rushing looks while playing opposite Von Miller this season.

Rousseau registered four solo tackles, one sack and one pass defense during Thursday's 31-10 win over the Rams.

EDGE Analysis

Rousseau tipped a pass intended for Cooper Kupp at the line in the first quarter and sacked Matthew Stafford on a third-and-short situation in the third quarter. The second-year defensive end played 45 of the team's 67 defensive snaps and will likely be a key piece in Buffalo's defense in 2022. As a rookie, the 2021 first-round pick recorded 50 tackles, four sacks, four pass defenses and one interception across 17 appearances.

Rousseau recorded seven tackles (five solo) in the Bills' 41-15 loss to the Colts on Sunday.

EDGE Analysis

Rousseau continues to make an impact on the defensive line in his rookie year. The Bills' 2021 first-round selection now has 33 tackles, three sacks, a pass defensed and an interception on the season.

Rousseau managed five tackles (four solo), one sack, one pass breakup and one interception during Sunday night's win over the Chiefs.

EDGE Analysis

Rousseau put together the best game of his young career against a fellow AFC powerhouse, bringing him to three sacks on the season. The rookie first-round pick earned AFC Defensive Player of the Week honors for his performance, and he'll get another primetime matchup Week 6 in the form of a Monday night road game in Tennessee.