Santillan picked up the save in Wednesday's 5-2 win over the Dodgers, striking out one in a clean ninth inning.

EDGE Analysis

Closer Emilio Pagan likely wasn't available after working four of the past five days for the Reds, which created the opportunity for Santillan to nab his third save of the season. Santillan owns a 1.96 ERA, 1.00 WHIP and 28:8 K:BB over 23 innings since the start of June, and he remains firmly in the high-leverage mix with 22 holds on the year.

Santillan struck out all three batters he faced over a scoreless seventh inning to earn a hold in Saturday's 5-2 win over the Mets.

EDGE Analysis

The Reds' bullpen protected a lead over the final four innings, including Santillan's quick dismissal of Juan Soto, Pete Alonso and Mark Vientos. The hold was Santillan's 20th in 2025, by far the most he's recorded in five seasons in the majors. Since the beginning of June, the right-handed reliever has a 2.55 ERA and 1.19 WHIP with 21 strikeouts and eight walks over 17.2 innings.

Santillan earned the save in Sunday's 4-2 win over the Diamondbacks, striking out one in a perfect ninth inning.

EDGE Analysis

Santillan was summoned to protect a two-run lead and needed just seven pitches to seal the win. It was an interesting move, as usual closer Emilio Pagan had thrown only 11 pitches in the ninth inning during Saturday's completion of Friday's suspended game. On the year, Santillan owns a 3.00 ERA, 1.03 WHIP and 23:9 K:BB across 30 innings with 13 holds and two saves.

Santillan blew the save after giving up one run on one hit and no walks in 1.1 innings during Wednesday's 8-6 extra-inning loss to the Giants.

EDGE Analysis

After recording two outs to close the seventh inning, Santillan served up a first-pitch fastball for a game-tying solo home run to Wilmer Flores. Santillan is working alongside Emilio Pagan for save opportunities in the absence of Alexis Diaz (hamstring), and the former has logged three holds while converting one of his two save chances to open the campaign. That said, Santillan does boast a 1.23 ERA and 0.68 WHIP with seven punchouts across 7.1 innings, and he should remain in the mix for ninth-inning work until Diaz rejoins the team.

Santillan retired the lone batter faced over a third of an inning to pick up the save in Monday's 2-0 win over the Giants.

EDGE Analysis

Hunter Greene attempted to finish what he started but allowed a two-out single and walk, which prompted manager Terry Francona to send in the cavalry. On this night, that was Santillan, who got Heliot Ramos to line out on a 3-1 four-seamer. The save was Santillan's first of the season and first since 2022. He's the third Reds reliever to log a ninth-inning save opportunity, as Francona does not appear to have a go-to guy since Alexis Diaz (hamstring) was removed from the role amid command issues this spring. Diaz is expected to make at least two more appearances while on rehab at Triple-A Louisville but is not guaranteed to get the closer's job back.

Reds manager Terry Francona indicated recently that he prefers to use Santillan "when we need to put the fire out" earlier in games, Charlie Goldsmith of the Dayton Daily News reports.

EDGE Analysis

Santillan pitched a scoreless eighth inning on Opening Day versus the Giants and a scoreless seventh inning Saturday, protecting a one-run lead on both occasions. While the 27-year-old looks to be Francona's most trusted reliever right now, Santillan looks like a better bet for holds than saves. Emilio Pagan appears to be the top closer option while Alexis Diaz (hamstring) is shelved.

Santillan pitched the seventh inning Saturday to get his second hold in as many games. Emilio Pagan later got the save.

EDGE Analysis

Santillan was brilliant Thursday in getting his first hold, striking out two batters. In this outing he gave up a single and didn't strike any batters out, but got out of the inning by inducing a double play grounder.

Reds manager Terry Francona said Wednesday that while Santillan is an "easy choice" to be the closer, "he might be too valuable getting to the ninth," Charlie Goldsmith of the Dayton Daily News reports.

EDGE Analysis

While Francona admitted he's not sure who his closer will be while Alexis Diaz (hamstring) is sidelined, it's notable that he mentioned Santillan in the fashion that he did, suggesting the right-hander might be the favorite to see the first opportunity. Santillan began last season in the minors after re-signing with the Reds last offseason on a minor-league deal, but he was excellent with the big club after being called up, posting a 3.00 ERA and 46:9 K:BB over 30 innings. Taylor Rogers, Scott Barlow, Graham Ashcraft and Emilio Pagan are other candidates to see save chances with the Reds.

Santillan will serve as the Reds' opening pitcher in Tuesday's game versus the Cubs, Mark Sheldon of MLB.com reports.

EDGE Analysis

Frankie Montas had been on turn to start Tuesday, but he was traded to the Brewers on Monday. Santillan is projected to work an inning or two in what will be a bullpen game for the Reds.

Cincinnati selected Santillan's contract from Triple-A Louisville on Saturday.

EDGE Analysis

The Reds placed starter Carson Spiers (shoulder) on the injured list Saturday and called up Santillan to take Spiers' roster spot, opting to add a reliever with the All-Star break looming. Santillan has logged a 3.38 ERA, 1.40 WHIP and 53:24 K:BB over 40.0 innings in the minors this season. He got into three games with the Reds last year, allowing one run on four hits while posting a 5:1 K:BB over 3.1 frames. He'll like serve in a low-leverage role while with the big-league club.