1st |
| Team | | Time | Down | Distance | Pos | Description | Score | Max Pts |
|---|
| SF | 1st | 15:00 | 1st | 10 | SF 25 | Carlos Hyde 5 yard Rushing Attempt Corey Graham | 0-0 | 0.5 |
| SF | 1st | 14:28 | 2nd | 5 | SF 30 | Colin Kaepernick 5 yard Rushing Attempt Corey Graham | 0-0 | 0.5 |
| SF | 1st | 14:05 | 1st | 10 | SF 35 | Quinton Patton 17 yard Passing Completion from Colin Kaepernick | 0-0 | 1.7 |
| SF | 1st | 13:52 | 1st | 10 | BUF 48 | Jeremy Kerley 7 yard Passing Completion from Colin Kaepernick Nickell Robey-Coleman | 0-0 | 0.7 |
| SF | 1st | 13:24 | 2nd | 3 | BUF 41 | Colin Kaepernick Incomplete Pass to Torrey Smith | 0-0 | |
| SF | 1st | 13:17 | 3rd | 3 | BUF 41 | Carlos Hyde 1 yard Rushing Attempt Leger Douzable | 0-0 | 0.1 |
| BUF | 1st | 12:30 | 1st | 10 | BUF 13 | Tyrod Taylor Incomplete Pass to Charles Clay | 0-0 | |
| BUF | 1st | 12:24 | 2nd | 10 | BUF 13 | LeSean McCoy 1 yard Rushing Attempt Eric Reid | 0-0 | 0.1 |
| BUF | 1st | 11:48 | 3rd | 9 | BUF 14 | Tyrod Taylor 9 yard Rushing Attempt Keith Reaser | 0-0 | 0.9 |
| BUF | 1st | 11:11 | 1st | 10 | BUF 23 | Tyrod Taylor Incomplete Pass | 0-0 | |
| BUF | 1st | 10:57 | 2nd | 21 | BUF 12 | LeSean McCoy 16 yard Rushing Attempt Ahmad Brooks | 0-0 | 1.6 |
| BUF | 1st | 10:15 | 3rd | 5 | BUF 28 | Robert Woods 8 yard Passing Completion from Tyrod Taylor Rashard Robinson | 0-0 | 0.8 |
| BUF | 1st | 9:41 | 1st | 10 | BUF 36 | Tyrod Taylor Rushing Attempt Fumble Lost recovered by DeForest Buckner Arik Armstead | 0-0 | 1 |
| SF | 1st | 9:36 | 1st | 10 | BUF 28 | Colin Kaepernick Incomplete Pass to Shaun Draughn | 0-0 | |
| SF | 1st | 9:31 | 2nd | 10 | BUF 28 | Carlos Hyde -1 yard Rushing Attempt Corey Graham | 0-0 | -0.1 |
| SF | 1st | 8:50 | 3rd | 11 | BUF 29 | Torrey Smith 15 yard Passing Completion from Colin Kaepernick Ronald Darby | 0-0 | 1.5 |
| SF | 1st | 7:54 | 1st | 20 | BUF 24 | Carlos Hyde 1 yard Rushing Attempt Jerry Hughes | 0-0 | 0.1 |
| SF | 1st | 7:12 | 2nd | 19 | BUF 23 | Colin Kaepernick -3 yard Rushing Attempt Zach Brown | 0-0 | -0.3 |
| SF | 1st | 6:27 | 3rd | 22 | BUF 26 | Quinton Patton 11 yard Passing Completion from Colin Kaepernick Preston Brown | 0-0 | 1.1 |
| SF | 1st | 5:47 | 4th | 11 | BUF 15 | Phil Dawson 33 yard Field Goal Made | 3-0 | 3 |
| BUF | 1st | 5:43 | 1st | 10 | BUF 25 | Charles Clay 20 yard Passing Completion from Tyrod Taylor Eric Reid | 3-0 | 2 |
| BUF | 1st | 5:25 | 1st | 10 | BUF 45 | LeSean McCoy 2 yard Rushing Attempt Tramaine Brock | 3-0 | 0.2 |
| BUF | 1st | 4:56 | 2nd | 8 | BUF 47 | E.J. Manuel 8 yard Rushing Attempt Rashard Robinson | 3-0 | 0.8 |
| BUF | 1st | 4:23 | 1st | 10 | SF 45 | Robert Woods 18 yard Passing Completion from Tyrod Taylor Antoine Bethea | 3-0 | 1.8 |
| BUF | 1st | 3:46 | 1st | 10 | SF 27 | LeSean McCoy 3 yard Rushing Attempt Antoine Bethea | 3-0 | 0.3 |
| BUF | 1st | 3:11 | 2nd | 7 | SF 24 | Robert Woods 7 yard Passing Completion from Tyrod Taylor Michael Wilhoite | 3-0 | 0.7 |
| BUF | 1st | 2:33 | 1st | 10 | SF 17 | LeSean McCoy 5 yard Rushing Attempt Nick Bellore | 3-0 | 0.5 |
| SF | 1st | 2:07 | 2nd | 5 | BUF 12 | Sack Arik Armstead | 3-0 | 2 |
| BUF | 1st | 1:21 | 3rd | 5 | SF 12 | Charles Clay 5 yard Passing Completion from Tyrod Taylor Keith Reaser | 3-0 | 0.5 |
| BUF | 1st | 0:46 | 1st | Goal | SF 7 | LeSean McCoy 3 yard Rushing Attempt Ahmad Brooks | 3-0 | 0.3 |
| BUF | 1st | 0:18 | 2nd | Goal | SF 4 | LeSean McCoy 4 yard Rushing TD | 3-6 | 6.4 |
| BUF | 1st | 0:14 | | | SF 15 | Dan Carpenter XP | 3-7 | 1 |
| SF | 1st | 0:14 | 1st | 10 | SF 25 | Colin Kaepernick 7 yard Rushing Attempt Preston Brown | 3-7 | 0.7 |
|
2nd |
| SF | 2nd | 15:00 | 2nd | 3 | SF 32 | Carlos Hyde 4 yard Rushing Attempt Corey Graham | 3-7 | 0.4 |
| SF | 2nd | 14:32 | 1st | 10 | SF 36 | Carlos Hyde 11 yard Rushing Attempt Kyle Williams | 3-7 | 1.1 |
| SF | 2nd | 14:07 | 1st | 10 | SF 47 | Torrey Smith 53 yard Passing TD from Colin Kaepernick | 9-7 | 13.3 |
| SF | 2nd | 13:56 | | | BUF 15 | Phil Dawson XP | 10-7 | 1 |
| BUF | 2nd | 13:56 | 1st | 10 | BUF 25 | Charles Clay 8 yard Passing Completion from Tyrod Taylor Nick Bellore | 10-7 | 0.8 |
| BUF | 2nd | 13:23 | 2nd | 2 | BUF 33 | LeSean McCoy 38 yard Rushing Attempt Eric Reid | 10-7 | 3.8 |
| BUF | 2nd | 12:41 | 1st | 10 | SF 29 | Tyrod Taylor 7 yard Rushing Attempt Eric Reid | 10-7 | 0.7 |
| BUF | 2nd | 12:17 | 2nd | 3 | SF 22 | Mike Gillislee 2 yard Rushing Attempt Quinton Dial | 10-7 | 0.2 |
| BUF | 2nd | 11:50 | 3rd | 1 | SF 20 | Mike Gillislee 2 yard Rushing Attempt Nick Bellore | 10-7 | 0.2 |
| BUF | 2nd | 11:07 | 1st | 10 | SF 18 | Nick O'Leary 6 yard Passing Completion from Tyrod Taylor Eric Reid | 10-7 | 0.6 |
| BUF | 2nd | 10:24 | 2nd | 4 | SF 12 | LeSean McCoy 12 yard Rushing TD | 10-13 | 7.2 |
| BUF | 2nd | 10:18 | | | SF 15 | Dan Carpenter XP | 10-14 | 1 |
| SF | 2nd | 10:18 | | | SF 35 | Torrey Smith 13 yard Kick Return Attempt Nickell Robey-Coleman | 10-14 | |
| SF | 2nd | 10:11 | 1st | 10 | SF 11 | Carlos Hyde 3 yard Rushing Attempt Jerel Worthy | 10-14 | 0.3 |
| SF | 2nd | 9:42 | 2nd | 7 | SF 14 | Colin Kaepernick 11 yard Rushing Attempt Zach Brown | 10-14 | 1.1 |
| SF | 2nd | 9:02 | 1st | 10 | SF 25 | Quinton Patton 13 yard Passing Completion from Colin Kaepernick Aaron Williams | 10-14 | 1.3 |
| SF | 2nd | 8:24 | 1st | 10 | SF 38 | Quinton Patton 11 yard Passing Completion from Colin Kaepernick Corey Graham | 10-14 | 1.1 |
| SF | 2nd | 7:50 | 1st | 10 | SF 49 | Carlos Hyde 15 yard Rushing Attempt Aaron Williams | 10-14 | 1.5 |
| SF | 2nd | 7:09 | 1st | 10 | BUF 36 | Torrey Smith 8 yard Passing Completion from Colin Kaepernick Ronald Darby | 10-14 | 0.8 |
| SF | 2nd | 6:42 | 2nd | 2 | BUF 28 | Carlos Hyde -2 yard Rushing Attempt Lorenzo Alexander | 10-14 | -0.2 |
| SF | 2nd | 6:03 | 3rd | 4 | BUF 30 | Colin Kaepernick Incomplete Pass to Jeremy Kerley Lorenzo Alexander | 10-14 | |
| SF | 2nd | 5:59 | 4th | 4 | BUF 30 | Phil Dawson 48 yard Field Goal Made | 13-14 | 4 |
| BUF | 2nd | 5:54 | 1st | 10 | BUF 25 | LeSean McCoy Rushing Attempt Nick Bellore | 13-14 | |
| BUF | 2nd | 5:15 | 2nd | 10 | BUF 25 | Charles Clay 5 yard Passing Completion from Tyrod Taylor DeForest Buckner | 13-14 | 0.5 |
| BUF | 2nd | 4:31 | 3rd | 5 | BUF 30 | Robert Woods 6 yard Passing Completion from Tyrod Taylor Eli Harold | 13-14 | 0.6 |
| BUF | 2nd | 3:43 | 1st | 10 | BUF 36 | Tyrod Taylor Incomplete Pass to Marquise Goodwin | 13-14 | |
| BUF | 2nd | 3:15 | 2nd | 20 | BUF 26 | Tyrod Taylor Incomplete Pass to LeSean McCoy | 13-14 | |
| BUF | 2nd | 3:10 | 3rd | 20 | BUF 26 | LeSean McCoy 22 yard Rushing Attempt Rashard Robinson | 13-14 | 2.2 |
| BUF | 2nd | 2:38 | 1st | 10 | BUF 48 | Mike Gillislee 4 yard Rushing Attempt Nick Bellore | 13-14 | 0.4 |
| BUF | 2nd | 2:00 | 2nd | 6 | SF 48 | Tyrod Taylor 10 yard Rushing Attempt Nick Bellore | 13-14 | 1 |
| BUF | 2nd | 1:29 | 1st | 10 | SF 38 | Tyrod Taylor 8 yard Rushing Attempt Rashard Robinson | 13-14 | 0.8 |
| BUF | 2nd | 1:22 | 1st | 2 | SF 30 | Robert Woods 6 yard Rushing Attempt Eric Reid | 13-14 | 0.6 |
| SF | 2nd | 0:47 | 1st | 10 | BUF 24 | Sack DeForest Buckner | 13-14 | 2 |
| BUF | 2nd | 0:38 | 2nd | 10 | SF 24 | LeSean McCoy 2 yard Passing Completion from Tyrod Taylor Nick Bellore | 13-14 | 0.2 |
| BUF | 2nd | 0:32 | 3rd | 8 | SF 22 | Tyrod Taylor Incomplete Pass to Marquise Goodwin | 13-14 | |
| BUF | 2nd | 0:25 | 4th | 8 | SF 22 | Dan Carpenter 40 yard Field Goal Made | 13-17 | 4 |
| SF | 2nd | 0:21 | | | SF 35 | Keshawn Martin 17 yard Kick Return Attempt Kevon Seymour | 13-17 | |
| SF | 2nd | 0:15 | 1st | 10 | SF 19 | Colin Kaepernick 16 yard Rushing Attempt | 13-17 | 1.6 |
|
3rd |
| BUF | 3rd | 15:00 | 1st | 15 | BUF 20 | Reggie Bush 1 yard Rushing Attempt Michael Wilhoite | 13-17 | 0.1 |
| BUF | 3rd | 14:04 | 2nd | 24 | BUF 11 | Tyrod Taylor Incomplete Pass to Charles Clay | 13-17 | |
| BUF | 3rd | 13:59 | 3rd | 24 | BUF 11 | Marquise Goodwin 16 yard Passing Completion from Tyrod Taylor Rashard Robinson | 13-17 | 1.6 |
| SF | 3rd | 13:21 | 4th | 8 | SF 27 | Jeremy Kerley 12 yard Punt Return Attempt Mike Gillislee | 13-17 | |
| SF | 3rd | 13:08 | 1st | 10 | SF 31 | Carlos Hyde 6 yard Rushing Attempt Preston Brown | 13-17 | 0.6 |
| SF | 3rd | 12:50 | 2nd | 4 | SF 37 | Colin Kaepernick Incomplete Pass to Torrey Smith | 13-17 | |
| SF | 3rd | 12:46 | 3rd | 9 | SF 32 | Colin Kaepernick Incomplete Pass to Jeremy Kerley | 13-17 | |
| BUF | 3rd | 12:29 | 1st | 10 | BUF 38 | LeSean McCoy 4 yard Rushing Attempt Quinton Dial | 13-17 | 0.4 |
| BUF | 3rd | 11:56 | 2nd | 6 | BUF 42 | LeSean McCoy Rushing Attempt Fumble recovered by LeSean McCoy Tramaine Brock | 13-17 | -1.4 |
| BUF | 3rd | 11:10 | 1st | 10 | BUF 43 | Tyrod Taylor 3 yard Rushing Attempt Keith Reaser | 13-17 | 0.3 |
| SF | 3rd | 10:42 | 2nd | 7 | SF 46 | Sack DeForest Buckner | 13-17 | 2 |
| BUF | 3rd | 9:59 | 3rd | 7 | BUF 46 | Tyrod Taylor Incomplete Pass to Justin Hunter Keith Reaser | 13-17 | |
| SF | 3rd | 9:45 | 1st | 10 | SF 5 | Mike Davis 1 yard Rushing Attempt Jerry Hughes | 13-17 | 0.1 |
| SF | 3rd | 9:13 | 2nd | 9 | SF 6 | Colin Kaepernick 10 yard Rushing Attempt Zach Brown | 13-17 | 1 |
| SF | 3rd | 8:36 | 1st | 10 | SF 16 | Jeremy Kerley 5 yard Passing Completion from Colin Kaepernick Aaron Williams | 13-17 | 0.5 |
| SF | 3rd | 8:07 | 2nd | 5 | SF 21 | Colin Kaepernick Incomplete Pass to Quinton Patton | 13-17 | |
| SF | 3rd | 7:59 | 3rd | 5 | SF 21 | Colin Kaepernick Incomplete Pass to Jeremy Kerley Nickell Robey-Coleman | 13-17 | |
| BUF | 3rd | 7:54 | 4th | 5 | BUF 21 | Brandon Tate 13 yard Punt Return Attempt Shayne Skov | 13-17 | |
| BUF | 3rd | 7:43 | 1st | 10 | BUF 45 | Marquise Goodwin 6 yard Passing Completion from Tyrod Taylor Tramaine Brock | 13-17 | 0.6 |
| BUF | 3rd | 7:09 | 2nd | 4 | SF 49 | Tyrod Taylor Incomplete Pass | 13-17 | |
| BUF | 3rd | 7:02 | 3rd | 4 | SF 49 | Tyrod Taylor Incomplete Pass to Robert Woods Tramaine Brock | 13-17 | |
| SF | 3rd | 6:51 | 1st | 10 | SF 20 | Colin Kaepernick Incomplete Pass to Quinton Patton Stephon Gilmore | 13-17 | |
| SF | 3rd | 6:47 | 2nd | 10 | SF 20 | Carlos Hyde 2 yard Rushing Attempt Jerry Hughes | 13-17 | 0.2 |
| SF | 3rd | 6:16 | 3rd | 8 | SF 22 | Colin Kaepernick 29 yard Rushing Attempt Stephon Gilmore | 13-17 | 2.9 |
| SF | 3rd | 5:47 | 1st | 10 | BUF 49 | Carlos Hyde 2 yard Rushing Attempt Leger Douzable | 13-17 | 0.2 |
| SF | 3rd | 5:19 | 2nd | 8 | BUF 47 | Mike Davis 7 yard Rushing Attempt Stephon Gilmore | 13-17 | 0.7 |
| SF | 3rd | 5:05 | 3rd | 1 | BUF 40 | Mike Davis Rushing Attempt Preston Brown | 13-17 | |
| SF | 3rd | 4:35 | 4th | 1 | BUF 40 | Mike Davis Rushing Attempt Preston Brown | 13-17 | |
| BUF | 3rd | 4:29 | 1st | 10 | BUF 40 | LeSean McCoy 12 yard Rushing Attempt Tramaine Brock | 13-17 | 1.2 |
| BUF | 3rd | 3:48 | 1st | 10 | SF 48 | LeSean McCoy -5 yard Rushing Attempt Nick Bellore | 13-17 | -0.5 |
| BUF | 3rd | 3:13 | 2nd | 15 | BUF 47 | Nick O'Leary 23 yard Passing Completion from Tyrod Taylor Antoine Bethea | 13-17 | 2.3 |
| BUF | 3rd | 2:40 | 1st | 10 | SF 30 | Justin Hunter 30 yard Passing TD from Tyrod Taylor | 13-23 | 9 |
| BUF | 3rd | 2:34 | | | SF 15 | Dan Carpenter XP | 13-24 | 1 |
| BUF | 3rd | 2:34 | 1st | 10 | BUF 25 | -1 yard Sack Zach Brown | 13-24 | 2 |
| SF | 3rd | 1:58 | 2nd | 11 | SF 24 | Vance McDonald 34 yard Passing Completion from Colin Kaepernick Ronald Darby | 13-24 | 3.4 |
| SF | 3rd | 1:40 | 1st | 10 | BUF 42 | Carlos Hyde 3 yard Rushing Attempt Corbin Bryant | 13-24 | 0.3 |
| SF | 3rd | 1:14 | 2nd | 7 | BUF 39 | Colin Kaepernick 8 yard Rushing Attempt Corey Graham | 13-24 | 0.8 |
| SF | 3rd | 0:28 | 1st | 10 | BUF 31 | Colin Kaepernick Incomplete Pass to Torrey Smith | 13-24 | |
| SF | 3rd | 0:21 | 2nd | 10 | BUF 31 | Carlos Hyde 2 yard Rushing Attempt Zach Brown | 13-24 | 0.2 |
|
4th |
| SF | 4th | 15:00 | 3rd | 8 | BUF 29 | Colin Kaepernick Incomplete Pass to Jeremy Kerley | 13-24 | |
| SF | 4th | 14:53 | 4th | 8 | BUF 29 | Phil Dawson 47 yard Field Goal Made | 16-24 | 4 |
| BUF | 4th | 14:48 | 1st | 10 | BUF 25 | LeSean McCoy -5 yard Rushing Attempt Arik Armstead | 16-24 | -0.5 |
| BUF | 4th | 14:11 | 2nd | 15 | BUF 20 | LeSean McCoy 7 yard Rushing Attempt Nick Bellore | 16-24 | 0.7 |
| BUF | 4th | 13:34 | 3rd | 8 | BUF 27 | Charles Clay 14 yard Passing Completion from Tyrod Taylor | 16-24 | 1.4 |
| BUF | 4th | 13:09 | 1st | 10 | BUF 41 | LeSean McCoy 7 yard Rushing Attempt Michael Wilhoite | 16-24 | 0.7 |
| BUF | 4th | 12:41 | 2nd | 3 | BUF 48 | Tyrod Taylor 8 yard Rushing Attempt Eric Reid | 16-24 | 0.8 |
| BUF | 4th | 12:04 | 1st | 10 | SF 44 | Mike Gillislee 5 yard Rushing Attempt DeForest Buckner | 16-24 | 0.5 |
| BUF | 4th | 11:37 | 2nd | 5 | SF 39 | Tyrod Taylor 21 yard Rushing Attempt Antoine Bethea | 16-24 | 2.1 |
| BUF | 4th | 10:59 | 1st | 10 | SF 18 | LeSean McCoy 18 yard Rushing TD | 16-30 | 7.8 |
| BUF | 4th | 10:53 | | | SF 15 | Dan Carpenter XP | 16-31 | 1 |
| BUF | 4th | 10:53 | | | BUF 35 | Keshawn Martin Fumble Lost recovered by Jonathan Meeks Nickell Robey-Coleman | 16-31 | 1 |
| BUF | 4th | 10:36 | 1st | Goal | SF 5 | Robert Woods 5 yard Passing TD from Tyrod Taylor | 16-37 | 6.5 |
| BUF | 4th | 10:32 | | | SF 15 | Dan Carpenter XP | 16-38 | 1 |
| SF | 4th | 10:32 | 1st | 10 | SF 25 | Mike Davis 5 yard Rushing Attempt Leger Douzable | 16-38 | 0.5 |
| SF | 4th | 10:10 | 2nd | 5 | SF 30 | Colin Kaepernick -12 yard Sack Lorenzo Alexander Fumble recovered by Joshua Garnett Leger Douzable | 16-38 | -2.8 |
| SF | 4th | 9:28 | 3rd | 17 | SF 18 | Colin Kaepernick Incomplete Pass | 16-38 | |
| BUF | 4th | 9:18 | 4th | 17 | BUF 18 | Brandon Tate 3 yard Punt Return Attempt Aaron Burbridge | 16-38 | |
| BUF | 4th | 9:05 | 1st | 10 | BUF 27 | Reggie Bush 5 yard Rushing Attempt Ahmad Brooks | 16-38 | 0.5 |
| BUF | 4th | 8:24 | 2nd | 5 | BUF 32 | Jonathan Williams 7 yard Rushing Attempt Eli Harold | 16-38 | 0.7 |
| BUF | 4th | 7:44 | 1st | 10 | BUF 39 | E.J. Manuel Incomplete Pass to Jerome Felton | 16-38 | |
| BUF | 4th | 7:39 | 2nd | 10 | BUF 39 | Jonathan Williams 3 yard Rushing Attempt DeForest Buckner | 16-38 | 0.3 |
| BUF | 4th | 6:43 | 3rd | 2 | BUF 47 | E.J. Manuel Incomplete Pass to Justin Hunter | 16-38 | |
| BUF | 4th | 6:27 | 1st | 10 | SF 48 | Mike Gillislee 4 yard Rushing Attempt Michael Wilhoite | 16-38 | 0.4 |
| BUF | 4th | 5:47 | 2nd | 6 | SF 44 | Mike Gillislee 44 yard Rushing TD | 16-44 | 12.4 |
| BUF | 4th | 5:40 | | | SF 15 | Dan Carpenter XP | 16-45 | 1 |
| SF | 4th | 5:40 | | | SF 35 | Jeremy Kerley 20 yard Kick Return Attempt Nickell Robey-Coleman | 16-45 | |
| SF | 4th | 5:34 | 1st | 10 | SF 37 | Colin Kaepernick Incomplete Pass to Mike Davis | 16-45 | |
| SF | 4th | 5:29 | 2nd | 10 | SF 37 | Vance McDonald 6 yard Passing Completion from Colin Kaepernick Zach Brown | 16-45 | 0.6 |
| SF | 4th | 4:50 | 3rd | 4 | SF 43 | Colin Kaepernick Incomplete Pass to Jeremy Kerley | 16-45 | |
| BUF | 4th | 4:37 | 1st | 10 | BUF 20 | Jonathan Williams Rushing Attempt Fumble Lost recovered by Nick Bellore Mike Purcell | 16-45 | 1 |
| SF | 4th | 4:28 | 1st | 10 | BUF 27 | Mike Davis 6 yard Passing Completion from Colin Kaepernick Ramon Humber | 16-45 | 0.6 |
| BUF | 4th | 4:21 | 2nd | 4 | SF 21 | -7 yard Sack Adolphus Washington | 16-45 | 2 |
| SF | 4th | 3:44 | 3rd | 11 | BUF 28 | Rod Streater 16 yard Passing Completion from Colin Kaepernick Preston Brown | 16-45 | 1.6 |
| SF | 4th | 3:37 | 1st | 10 | BUF 12 | Colin Kaepernick Incomplete Pass to Mike Davis | 16-45 | |
| SF | 4th | 3:33 | 2nd | 10 | BUF 12 | Shaun Draughn 2 yard Rushing Attempt Ramon Humber | 16-45 | 0.2 |
| SF | 4th | 2:50 | 3rd | 8 | BUF 10 | Colin Kaepernick Incomplete Pass to Quinton Patton Duke Williams | 16-45 | |
| SF | 4th | 2:41 | 4th | 8 | BUF 10 | Colin Kaepernick Incomplete Pass to Torrey Smith Ronald Darby | 16-45 | |
| BUF | 4th | 2:34 | 1st | 10 | BUF 11 | Jonathan Williams 1 yard Rushing Attempt DeForest Buckner | 16-45 | 0.1 |
| BUF | 4th | 2:00 | 2nd | 9 | BUF 12 | Jonathan Williams 6 yard Rushing Attempt Michael Wilhoite | 16-45 | 0.6 |
| BUF | 4th | 1:13 | 3rd | 3 | BUF 18 | E.J. Manuel 4 yard Rushing Attempt Cornellius Carradine | 16-45 | 0.4 |
| BUF | 4th | 0:31 | 1st | 10 | BUF 22 | E.J. Manuel -1 yard Rushing Attempt | 16-45 | -0.1 |