Williams (knee) said Tuesday that he should be 100 percent healthy for the beginning of training camp in late July, Matt Barrows of The Athletic reports.

EDGE Analysis

Williams missed the final 10 games of his rookie season after tearing the ACL and lateral meniscus in his right knee during the 49ers' Week 9 win over the Giants. The 2025 first-round pick from Georgia played a minimal role during his debut campaign, recording a sack and 20 total tackles across 383 defensive snaps.

The 49ers placed Williams (knee) on injured reserve Saturday.

EDGE Analysis

Williams suffered a torn ACL in last Sunday's win over the Giants and will miss the remainder of the season. He joins a laundry list of 49ers on the team's injured-reserve list. The 11th overall pick in the 2025 NFL Draft, Williams wraps up his rookie season with 20 tackles (11 solo), including 1.0 sacks, and one fumble recovery across nine appearances, all starts. San Francisco will lean on Bryce Huff, Keion White (groin), Sam Okuayinonu, Robert Beal and Clelin Ferrell at defensive end moving forward.

Head coach Kyle Shanahan said Monday that Williams tore his ACL during the fourth quarter of Sunday's 34-24 win over the Giants, Matt Barrows and Dianna Russini of The Athletic report.

EDGE Analysis

Shanahan noted that there was some damage to the lateral meniscus in Williams' knee but no other ligament damage beyond the ACL, which means the rookie first-rounder has a chance to be available for the start of the 2026 campaign. It's yet another season-ending injury for the 49ers defense, with Williams stepping into a larger role on the defensive line after Nick Bosa tore his ACL in Week 3 against the Cardinals and All-Pro linebacker Fred Warner lost for the season after dislocating and fracturing his right ankle in Week 6 against the Buccaneers. Fellow defensive end Yetur Gross-Matos will miss at least three more games while on injured reserve due to a hamstring injury, but veteran Bryce Huff (hamstring) is expected to return from a two-game absence against the Rams in Week 10. In the absence of Bosa, Gross-Matos and now Williams, the 49ers will rely more heavily on the likes of Huff, Sam Okuayinonu, Clelin Ferrell and Keion White (who was traded by New England to San Francisco this past Tuesday) at defensive end. Barrows and Russini also note that the 49ers are looking to add to the position before Tuesday's 4 p.m. ET deadline and have shown interest in Jaelan Phillips (who the Eagles acquired from the Dolphins on Monday), Bradley Chubb and Matthew Judon.

Head coach Kyle Shanahan said Mykel Williams might have injured his ACL in Sunday's win over the Giants, Vic Tafur of The Athletic reports.

EDGE Analysis

Williams will undergo further testing Monday to confirm whether he suffered an ACL injury. If the 21-year-old is forced to miss extended time, Sam Okuayinonu would likely start at defensive end in his place.

Williams logged a full practice session Wednesday, Matt Barrows of The Athletic reports.

EDGE Analysis

Williams suffered a wrist injury in 49ers' win over Arizona on Sunday, but he was able to return. His full practice session Wednesday suggests he should be ready to suit up for a Week 4 matchup against Jacksonville.

Williams is considered day-to-day due to a wrist injury, Nick Wagoner of ESPN.com reports.

EDGE Analysis

Williams hurt his wrist in Sunday's Week 3 win over the Cardinals but was able to finish the game after initially being labeled as questionable to return. He logged 65 percent of the 49ers' defensive snaps in the victory and finished with two tackles. Given that he was able to return after getting hurt, there's reason to be optimistic that Williams will be able to suit up Sunday against Jacksonville, though his level of participation in practice this week should provide better insight into whether he'll have an injury designation heading into the weekend.

Williams (wrist) has returned to Sunday's contest against the Cardinals, Nick Wagoner of ESPN.com reports.

EDGE Analysis

Williams exited the game in the second quarter with a wrist injury, but he has now returned to action. With Nick Bosa (knee) done for the day, Williams will have an increase in importance the rest of the way in Week 3.

Williams is questionable to return to Sunday's game against the Cardinals due to a wrist injury, Matt Barrows of The Athletic reports.

EDGE Analysis

Williams appeared to suffer the injury in the second quarter and was seen running to the locker room after being initially checked on by trainers in the blue medical tent. With Nick Bosa (knee) also questionable to return, the 49ers are down to Yetur Gross-Matos, Bryce Huff and Sam Okuayinonu as their defensive ends.

Williams (knee) practiced in full Wednesday, Cam Inman of The San Jose Mercury News reports.

EDGE Analysis

The rookie first-rounder ended up missing all three of the 49ers' preseason games due to a knee injury that he suffered in early August. Williams was able to log a full practice to open the week, indicating that he is on track to make his NFL regular-season debut against the Seahawks on Sunday. He's expected to see a prominent role on the 49ers' defensive front alongside Nick Bosa, Kalia Davis and Jordan Elliott.

Williams (knee) has been ruled out for Saturday's preseason game against Las Vegas, Eric Branch of the San Francisco Chronicle reports.

EDGE Analysis

Williams is currently working through a knee injury, which also prevented him from playing in the 49ers' preseason opener against the Broncos. The injury isn't considered a serious one at this time, but the rookie first-rounder will aim to return to practice next week in order to be cleared to play in the 49ers' preseason finale against the Chargers on Saturday, Aug. 23.