The Cowboys placed Sanders (knee/ankle) on injured reserve Saturday.

EDGE Analysis

After Executive Vice President Stephen Jones announced Friday that Sanders was slated for season-ending knee surgery, this move was inevitable. Moving forward, rookie Jaydon Blue and fullback Hunter Luepke will be the options out of the Cowboys backfield behind starter Javonte Williams.

Executive Vice President Stephen Jones said Friday that Sanders will undergo season-ending knee surgery, Todd Archer of ESPN.com reports.

EDGE Analysis

Sanders initially was forced out Week 4 against the Packers due to an ankle injury and then didn't suit up this past Sunday at the Jets due to listed knee and ankle issues. It appears the knee is the greater concern for Sanders following Jones' announcement, and the running back will finish the 2025 campaign with 20 carries for 117 yards and one touchdown and eight catches (on eight targets) for 30 yards in parts of four games. Jaydon Blue will step into the No. 2 role behind starting RB Javonte Williams moving forward.

Sanders (knee/ankle) will miss the rest of the season, Jon Machota of The Athletic reports.

EDGE Analysis

Cowboys EVP Stephen Jones said the team is "fired up" about what Jaydon Blue can do as the No. 2 running back. The rookie had just seven yards on four touches in the first game Sanders missed, with Javonte Williams again dominating backfield work. In any case, Sanders apparently will be placed on injured reserve soon.

Sanders (ankle) didn't participate in Thursday's practice.

EDGE Analysis

Sanders opened Week 6 prep Wednesday as a limited participant, but his lack of activity Thursday doesn't inspire much early confidence that he'll be able to return from a one-game absence to play Sunday at Carolina. If Sanders isn't available for the matchup with one of his former teams, the Cowboys would likely keep rookie Jaydon Blue active for the second week in a row as starting running back Javonte Williams' top backup.

Sanders (knee/ankle) was a limited participant in Wednesday's practice, Jon Machota of The Athletic reports.

EDGE Analysis

Sanders didn't practice at all prior to being ruled out for Dallas' win over the Jets in Week 5, so it's notable to see that he was upgraded to limited activity. If the veteran running back is able to gain clearance in time to suit up Sunday against the Panthers, he'll join Jaydon Blue as a reserve option behind No. 1 running back Javonte Williams.

Sanders (knee/ankle) is inactive for Sunday's game at the Jets, Nick Harris of the Fort Worth Star-Telegram reports.

EDGE Analysis

Sanders wasn't able to practice during Week 5 prep due to knee and ankle injuries, but a questionable designation left the door open for him to be available to the Cowboys offense Sunday. The proceeding didn't come to pass, though, so Dallas will roll with rookie fifth-round pick Jaydon Blue and fullback Hunter Luepke as the backfield options behind starter Javonte Williams. Sanders' next chance to suit up is Sunday, Oct. 12 in Carolina.

Sanders (knee/ankle) is listed as questionable for Sunday's game at the Jets, Todd Archer of ESPN.com reports.

EDGE Analysis

Since exiting the Cowboys' Week 4 tie with the Packers just before halftime, Sanders was diagnosed with a right ankle injury and then didn't practice Wednesday through Friday due to listed knee and ankle issues. Despite the lack of activity this week, the team is giving him a chance to be available to the offense Sunday, which will be confirmed about 90 minutes before a 1:00 p.m. kickoff. If Sanders is inhibited or sidelined, Jaydon Blue and Hunter Luepke would be the candidates for RB reps behind starter Javonte Williams, with Malik Davis a candidate to be elevated from the practice squad.

Sanders (knee/ankle) didn't practice Thursday, Calvin Watkins of The Dallas Morning News reports.

EDGE Analysis

Sanders made an early exit from this past Sunday's tie with the Packers due to an ankle injury and so far has been listed as a non-participant on the Cowboys' Week 5 practice report due to knee and ankle issues. On Wednesday, he told Calvin Watkins of The Dallas Morning News that he had an MRI on his right ankle, and also that he'll attempt to run by Friday, which will determine his availability for Sunday's game at the Jets. If Sanders is inhibited or sidelined this weekend, rookie fifth-round pick Jaydon Blue could make his pro debut behind workhorse RB Javonte Williams.

Sanders (knee/ankle) was a non-participant at Wednesday's practice, Nick Harris of the Fort Worth Star-Telegram reports.

EDGE Analysis

Sanders exited this past Sunday's tie with the Packers just before halftime due to an ankle injury, but coach Brian Schottenheimer told Joe Hoyt of The Dallas Morning News on Monday that the running back was trending toward being able to play Week 5 at the Jets. On Wednesday, Sanders himself said he had an MRI on his right ankle, and the Cowboys will have a better idea of his upcoming availability, or lack thereof, if he's able to run by Friday, according to Calvin Watkins of The Dallas Morning News. As such, Sanders' status will be monitored as the week goes on to see if he'll be able to continue in his complementary role behind Javonte Williams on Sunday.

Coach Brian Schottenheimer said Monday that Sanders (ankle) is trending toward being able to play Sunday against the Jets, Joe Hoyt of The Dallas Morning News reports.

EDGE Analysis

Sanders left this past Sunday night's tie against the Packers in the second quarter and was unable to return. However, it sounds like he avoided a serious injury. Sanders has been operating as the change-of-pace option behind Javonte Williams in Dallas' backfield to begin the season.