Murphy's teammate Taiwan Jones has been ruled out for Sunday's game in Indianapolis due to a neck injury.

EDGE Analysis

Murphy hasn't suited up in three games, once due to injury and two as a heathy scratch, but it looks like he might get a chance to play this week as a replacement for Jones in the return game and as a depth running back. However, with both LeSean McCoy and Chris Ivory healthy, even if Murphy does play it's unlikely he'll see more than a few carries.

Murphy is inactive for Sunday's game in Houston, CChris Brown of the Bills' official site reports.

EDGE Analysis

This will make three straight missed games for the formerly promising fantasy hope, one due to injury and two due to healthy scratches. With LeSean McCoy and Chris Ivory both healthy, and Taiwan Jones being a better special teams option, Murphy has taken a back seen in the team's plans for now.

Murphy will not suit up for Sunday's game against the Titans, Chris Brown of the Bills' official site reports.

EDGE Analysis

Murphy appears mostly healthy after dealing with a rib injury recently, but apparently the Bills feel comfortable with LeSean McCoy, Chris Ivory and Taiwan Jones manning their backfield this week. Murphy has been dropkicked after having a short window of value earlier this season when McCoy was out with an injury, but Ivory has retaken the No. 2 spot and Jones is a more rounded special teams player.

Murphy (ribs) practiced fully Friday for the third straight day and does not appear on the injury report for Sunday's game against the Titans, the Bills' official site reports.

EDGE Analysis

Murphy sat out the Week 4 loss to the Packers, but he'll be available in a reserve role for Sunday's contest. With LeSean McCoy and Chris Ivory both relatively healthy ahead of him, expect Murphy's touches to be relatively scarce. He could factor in as a returner, however.

Murphy, who missed last week's game with an injury to his ribs, was able to practice fully Wednesday, Chris Brown of the Bills' official site reports.

EDGE Analysis

It looks like Murphy will be back in the mix for Sunday's game against the Titans, but with LeSean McCoy and Chris Ivory mostly healthy his role is likely limited to a depth option and special teams guy.

Coach Sean McDermott expects Murphy (ribs) to be fine moving forward, Mike Rodak of ESPN.com reports.

EDGE Analysis

Murphy was held out of Sunday's 22-0 loss to the Packers after logging limited practices throughout the week. He seems to be on track for a return Week 5 against the Titans, but his role on offense likely will be limited now that the Bills have LeSean McCoy (hand, ribs) available.

Murphy (ribs) is listed as inactive Sunday against Green Bay.

EDGE Analysis

Despite logging limited practices all week, Murphy will take a seat from his role as a reserve running back and occasional kick returner. The return of LeSean McCoy (ribs) likely made this an easier decision for the Bills, who also have Chris Ivory on hand to serve in a backup capacity.

Murphy (ribs) is listed as questionable for Sunday's game at Green Bay.

EDGE Analysis

Murphy was a limited participant at practice this week to earn the questionable tag, along with starting RB LeSean McCoy. If Murphy is able to suit up Sunday, his potential value will largely hinge on McCoy's status with Chris Ivory still ahead of him on the depth chart.

Murphy (ribs) was spotted in a non-contact jersey during the portion of Thursday's practice that was available to the media, Mike Rodak of ESPN.com reports.

EDGE Analysis

The Bills listed Murphy as a limited participant in practice Wednesday when he was also withheld from contact work, so he'll likely receive the same designation a day later. Fellow running back LeSean McCoy also didn't take contact Thursday while continuing to deal with cracked ribs, but McCoy has stated that he intends to play Sunday in Green Bay. If both McCoy and Murphy are ultimately cleared to suit up in Week 4, the latter probably wouldn't be in store for much work out of the backfield behind McCoy and Chris Ivory.

Bills head coach Sean McDermott said Wednesday that Murphy is dealing with a rib injury, Vic Carucci of The Buffalo News. Murphy will be a limited participant in the Bills' first practice of Week 4, Matthew Fairburn of The Athletic reports.

EDGE Analysis

It's unclear if Murphy's injury is severe as that of starting running back LeSean McCoy, who is recovering from cracked ribs. In any event, both players will likely be withheld from contact work at Wednesday's session, leaving Chris Ivory and special teamer Taiwan Jones as the only healthy tailbacks on the roster. Murphy would likely assuage some concern about his injury by advancing to full practice by the end of the week, but his fantasy outlook will be tied to the health of McCoy, who hasn't been ruled out from returning to action Sunday against the Packers. While McCoy sat out the Week 3 win over the Vikings, Murphy served as the clear No. 2 option out of the backfield, logging only 16 offensive snaps to Ivory's 54 and getting out-touched by a 23-9 margin.