Mustapha wrapped up 76 combined tackles (44 solo) and defended three passes (one interception) across 12 regular-season starts in 2025.

EDGE Analysis

Mustapha opened the regular season on the PUP list after undergoing successful surgery on the knee he injured at the tail end of the 2024 campaign. The sophomore safety only missed one game past the minimum four-week requirement and looked as dominant as he did prior to tearing his ACL. Mustapha reclaimed his starting strong safety job in Week 6 and still surpassed last year's tackle total (72) despite appearing in four fewer games. The 23-year-old will attempt to combine good health with continued strong play while starting alongside Ji'Ayir Brown in 2026.

Mustapha registered three tackles (two solo) and one pass defense during San Francisco's 42-38 win over Chicago on Sunday.

EDGE Analysis

Mustapha played every single defensive snap during Sunday's win, but his three tackles were his lowest since Week 6 against the Buccaneers (two). The second-year safety is up to 71 combined tackles across 11 regular-season games, which is one stop shy from matching his total from his rookie campaign across 16 regular-season games. Mustapha should surpass that mark during the 49ers' Week 18 tilt against the Seahawks on Saturday, a game that will determine who captures the NFC West and enters the postseason as the No. 1 seed in the conference.

Mustapha tallied eight tackles (three solo) in Monday's 48-27 victory against Indianapolis.

EDGE Analysis

Mustapha's tackle total was third-highest on San Francisco. The second-year safety has been a steady IDP asset of late, posting at least seven stops in each of his past four games.

Mustapha logged 10 tackles (six solo) during the 49ers' win over the Titans on Sunday.

EDGE Analysis

Mustapha was San Francisco's leading tackler during the victory, and he has now compiled double-digit stops twice this season. The 23-year-old will look to build on this strong performance and keep producing during the team's Week 16 matchup versus the Colts.

Mustapha recorded seven tackles (seven solo) and one tackle for loss in Monday's 20-9 win over the Panthers.

EDGE Analysis

Mustapha led San Francisco in tackles and also logged his highest solo-tackle total this season. He now has at least seven total tackles in three of seven contests for the campaign.

Mustapha logged four tackles (one solo) and an interception during San Francisco's win over the Cardinals on Sunday.

EDGE Analysis

Mustapha managed to force his first turnover of the season when he picked off Jacoby Brissett late in the second quarter of the victory. The 23-year-old was sidelined for the first five weeks of the season with a knee injury but has gotten off to a strong start since making his return, recording 36 tackles (18 solo) and an interception across six outings.

Mustapha notched eight tackles (four solo) in Sunday's loss to the Rams.

EDGE Analysis

Mustapha tied for third among 49ers defenders in tackles in defeat. The second-year safety missed the first five weeks of the season, but since his return he's tallied 32 tackles across five contests while logging 100 percent of San Francisco's defenders each of the past three weeks.

Mustapha made 12 tackles (six solo) during Sunday's loss to the Texans.

EDGE Analysis

Mustapha played a season-high 100 percent of defensive snaps in Week 8, after having made his debut Week 6 then having his workload jump Week 7. The second-year pro appears to have solidified himself as an every-down player as the 49ers prepare for a Week 9 road matchup against the Giants. That development puts him firmly on the fantasy radar in IDP formats.

Mustapha tallied six tackles (three solo) Sunday in a 20-10 win over the Falcons.

EDGE Analysis

After beginning the campaign on IR, Mustapha returned in Week 6 and logged a 38 percent snap share. The second-year safety's workload jumped significantly in Week 7, as Mustapha was on the field for 69 percent of the 49ers' defensive snaps. David Lombardi of SFStandard.com suggests that Mustapha will ultimately be a regular starter while Sigle, Pinnock and Ji'Ayir Brown -- who played every defensive snap Sunday -- contend for the No. 2 spot.

Mustapha (knee) is active for Sunday's game against the Buccaneers, Briana Jeannel of the 49ers' official site reports.

EDGE Analysis

Mustapha is ready to make his 2025 debut after fully recovering from a torn ACL that he suffered in January. With how well rookie fifth-rounder Marques Sigle has been playing this season, Mustapha may work in a rotational role in the secondary and on special teams in his return.