Jake Brendel
SF (14)
Fri 11/7/25 10:32 PM

Brendel (hamstring) does not have an injury designation for Sunday's battle against the Rams, Nick Wagoner of ESPN.com reports.
EDGE Analysis
Brendel hurt his hamstring in Week 7 against Atlanta and missed San Francisco's subsequent two contests. However, he was able to log an LP/LP/FP practice progression this week and has been given clearance to return to action Sunday. Matt Hennessy has done a serviceable job filling in at center the past two weeks, but Brendel figures to retake his starting role against the Rams.

Jake Brendel
SF (14)
Fri 10/31/25 10:07 PM

Brendel (hamstring) was ruled out ahead of Sunday's matchup against the Giants,Jennifer Lee Chan of NBC Sports Bay Area reports.
EDGE Analysis
Brendel originally suffered the injury in Week 7 against the Falcons and will be set for his second consecutive absence. He has yet to practice since getting hurt.

Jake Brendel
SF (14)
Wed 10/29/25 10:32 PM

Brendel (hamstring) didn't participate in San Francisco's practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
EDGE Analysis
Brendel remains sidelined with the knee injury he suffered in the team's Week 7 win over the Falcons. Matt Hennessy will start at center for the second straight week if Brendel is unable to suit up for Sunday's matchup against the Giants.

Jake Brendel
SF (14)
Fri 10/24/25 7:43 PM

Brendel (hamstring) is listed as out for Sunday's game at Houston, Nick Wagoner of ESPN.com reports.
EDGE Analysis
Brendel will miss his first game of the season in Week 8 due to a hamstring injury he suffered in Week 7 versus the Falcons. In his absence, Matt Hennessy projects to start at center Sunday at Houston.

Jake Brendel
SF (14)
Mon 10/20/25 6:44 PM

Head coach Kyle Shanahan said Monday that Brendel is expected to be sidelined for a couple of weeks due to a hamstring injury, Matt Maiocco of NBC Sports Bay Area reports.
EDGE Analysis
Brendel sustained the injury during the 49ers' 20-10 win over the Falcons on Sunday. He started at center in each of the first seven games of the regular season, and his absence means Matt Hennessy will likely take over the as the 49ers' center for as long as Brendel is on the shelf.

Jake Brendel
SF (14)
Sun 10/19/25 9:34 PM

Brendel has a hamstring injury and has been ruled out for the rest of Sunday night's matchup with the Falcons, Matt Maiocco of NBC Sports Bay Area reports.
EDGE Analysis
The veteran has started all seven games this season and every 49ers game dating back to 2021. Matt Hennessy is his backup.

Jake Brendel
SF (14)
Tue 3/14/23 2:10 PM

Brendel and the 49ers agreed to terms on a four-year contract Tuesday, NFL Network's Ian Rapoport reports.
EDGE Analysis
Brendel became a full-time starter as a 30-year-old last season, making all 17 starts at center after logging just three career starts prior to 2022. It's a big re-signing for the Niners after they reportedly lost stalwart RT Mike McGlinchey to the Broncos on Monday.

Jake Brendel
SF (14)
Thu 9/2/21 2:33 PM

Brendel signed a contract with the 49ers on Wednesday.
EDGE Analysis
Brendel was cut by San Francisco ahead of Tuesday's roster deadline but re-signed with the team a day later. The 28-year-old opted out of the 2020 campaign and should provide depth at center for the 49ers.

Jake Brendel
SF (14)
Thu 8/6/20 11:32 PM

Brendel has opted out of the 2020 season, Nick Wagoner of ESPN.com reports.
EDGE Analysis
The journeyman center spent time in Dallas, Miami, Denver and Baltimore before signing a contract with the 49ers earlier this year. He is the third member of the 49ers to opt out of the season.

Jake Brendel
SF (14)
Mon 2/10/20 11:13 PM

Brendel signed a contract with the 49ers on Monday.
EDGE Analysis
Brendel was cut loose by the Ravens at the end of November, but he'll now get a shot with San Francisco to win a roster spot. He's bounced around since being signed by the Cowboys as an undrafted free agent in 2016, spending time in Dallas, Miami, Denver and Baltimore.