Brissett completed 22 of 31 pass attempts for 243 yards, two touchdowns and an interception while gaining 19 yards and losing a fumble on three carries in Sunday's 37-20 loss to the Rams.

EDGE Analysis

Brissett rallied Arizona in the second half with touchdown passes to WR Michael Wilson and TE Josiah Deguara to give his club a 20-16 lead. That woke up Matthew Stafford and the Rams' offense, who then responded with three touchdowns to hand the Cardinals their ninth straight loss to end the year. Brissett was one of the few bright spots for Arizona in a forgettable 2025 campaign. The journeyman backup took over for an injured and struggling Kyler Murray back in Week 6 and played so well that head coach Jonathan Gannon named Brissett the starter for the rest of the year. The 32-year-old Brissett became a hot fantasy add while posting career highs in passing yards (3,367) and touchdown passes (23) across 12 starts. Both Murray and Brissett are under contract with the Cardinals for the 2026 season, so it will be interesting to see how the franchise handles its QB situation this upcoming offseason.

Brissett completed 21 of 37 passes for 212 yards and two touchdowns in Sunday's 37-14 loss to the Bengals.

EDGE Analysis

The Cardinals defense had no success at all slowing down Joe Burrow, so Brissett's efforts -- which included a 38-yard TD to Michael Wilson in the second quarter and an 18-yard score to Trey McBride in the fourth -- didn't make much impact. The veteran has tossed multiple touchdowns in nine of his 11 starts this season, posting a 21:7 TD:INT over that stretch as he makes a case for a starting job in 2026, whether with Arizona or someone else. With an undrafted rookie in Kedon Slovis as his backup, Brissett could still be under center in Week 18 against the Rams, even with nothing on the line for the Cards but draft position.

Brissett completed 16 of 31 pass attempts for 203 yards, one touchdown and one interception while taking his only carry for five yards in Sunday's 26-19 loss to Atlanta.

EDGE Analysis

Brissett barely completed 50 percent of his pass attempts in his worst start since taking over for Kyler Murray (foot) back in Week 6. The 27-year-old Brissett recorded his lowest passing yardage total through 10 starts while being held to a single touchdown scored for just the second time this year. Brissett had been a revelation over his previous nine appearances with the Cardinals, so fantasy managers can hold out hope for a bounce-back effort in a soft matchup against Cincinnati in Week 17.

Brissett completed 27 of 40 passes for 249 yards and three touchdowns with one interception in Sunday's 40-20 loss to the Texans. He added six rushing yards on three carries.

EDGE Analysis

For the second straight game, the Arizona defense coughed up at least 40 points, letting another strong performance from Brissett go to waste. The three TDs -- two to Trey McBride and one to Michael Wilson -- were a season high for the veteran QB, but Brissett has tossed multiple scores in eight of the last nine games, posting an impressive 18:6 TD:INT since taking over for Kyler Murray (foot) in Week 6. Brissett will look to establish a new career high in passing TDs on the season in Week 16 against the Falcons.

Brissett completed 25 of 44 pass attempts for 271 yards, two touchdowns and one interception while adding 22 rushing yards on four attempts in Sunday's 45-17 loss to the Rams.

EDGE Analysis

Brissett got off to a hot start when he drove his team down the field for a touchdown pass on the game's opening possession. The veteran signal-caller was clamped down from there salvaging his day from a fantasy perspective with a garbage-time touchdown in the fourth quarter. Brissett's three-game streak of reaching 300 passing yards came to an end Sunday, but he is still posting voluminous passing numbers while starting for the fledgling Cardinals. Kyler Murray (foot) has still not been reinstated off injured reserve, leaving Brissett to handle a rough road matchup against the Texans next Sunday.

Coach Jonathan Gannon announced Monday that Kyler Murray (foot) won't be designated for return from injured reserve this week, setting up Brissett for another start Sunday versus the Rams, Darren Urban of the Cardinals' official site reports.

EDGE Analysis

During Murray's current seven-game absence as he tends to a mid-foot sprain, Brissett has eclipsed 300 yards passing four times and tossed exactly two touchdowns on six occasions. Overall, Brissett has completed 67.8 percent of his passes (204 of 301) for 2,188 yards with a 13:4 TD:INT while adding 26 carries for 114 yards and another score during that span. In Week 14, he'll be taking on a Rams defense that has surrendered the seventh-fewest yards per attempt (6.5) to opposing quarterbacks this season, so the sledding may be a bit tougher for Brissett this time around.

Brissett completed 29 of 40 passes for 301 yards with two touchdowns and one interception while adding three carries for 16 yards in the Cardinals' 20-17 loss to the Buccaneers on Sunday.

EDGE Analysis

Brissett put together another impressive statistical showing in the return of Marvin Harrison from a two-game absence due to an appendectomy. Brissett connected with his No. 1 wideout on six occasions for 69 yards, and he spread the ball around to seven different pass catchers overall. The veteran signal-caller had the ball in his hands with a chance to drive the Cardinals into position for a potential game-tying field goal late in the fourth quarter, but Brissett threw incomplete on consecutive plays to snuff out that possibility and turn the ball over on downs. Despite Sunday's loss, Brissett has effectively moved the offense each week, and considering Ian Rapoport of NFL Network reported Sunday that Kyler Murray (IR, foot), despite being eligible to have his practice window opened this coming week, still isn't fully recovered, Brissett appears highly likely to remain the starter in a Week 14 home matchup against the Rams next Sunday.

Brissett completed 33 of 49 pass attempts for 317 yards and a touchdown while taking three carries for 20 yards in Sunday's 27-24 loss to Jacksonville in overtime.

EDGE Analysis

Brissett continued his gun-slinging ways by eclipsing 300 passing yards for the third time in six starts filling in for Kyler Murray (foot). The 32-year-old Brissett failed to extend his streak of throwing multiple touchdown passes to six games, but it was still another impressive effort from a fantasy perspective. Brissett did leave the game briefly in the second half to be evaluated by the medical staff after taking a big hit, but he promptly returned to action and finished the remainder of the game plus overtime without issue. The journeyman backup has already been named Arizona's starter for the remainder of the season, so fantasy managers who took a chance on Brissett during his current run as starter can feel comfortable continuing to roll him out on a weekly basis. The Cardinals will hit the road in Week 13 to face the Buccaneers, who currently sit in the bottom third of the league in terms yards allowed to opposing quarterbacks.

Brissett completed 47 of 57 passes for 452 yards, two touchdowns and two interceptions and rushed twice for minus-2 yards during Sunday's 41-22 loss to the 49ers.

EDGE Analysis

Working without No. 1 WR Marvin Harrison (concussion) on Sunday, Brissett set an NFL record for a single game with his 47 completions, helping fuel a pair of 100-yard receiving efforts from WR Michael Wilson (15-185-0 on 18 targets) and TE Trey McBride (10-115-1 on 11 targets). The pass-heavy approach from the Cardinals likely was spurred by being down double-digit points as soon as the 13:39 mark of the second quarter, and the closest margin after that point was nine points before the 49ers tacked on a pair of field goals in the last 1:01 of the first half. In five starts in place of Kyler Murray (foot, IR), Brissett has averaged 314 yards per game to go with a 10:3 TD:INT on 67 percent passing. Brissett's next chance to continue leading Arizona's offense is next Sunday versus the Jaguars.

Brissett completed 22 of 44 pass attempts for 258 yards and two touchdowns while gaining 31 yards on four carries and losing two fumbles in Sunday's 44-22 loss to Seattle.

EDGE Analysis

Brissett's improbable victory over the Cowboys last week was put out of mind after Arizona was greeted by the Seahawks with a 35-0 deficit in the first half. The veteran signal-caller salvaged his day by compiling stats in garbage time, producing his fourth straight start of 250 or more passing yards and two touchdowns thrown. Brissett has great shot at extending his streak of fantasy production against an injury-riddled 49ers defense next Sunday.