The Lions placed Ragnow (hamstring) on the reserve/retired list Monday, Dave Birkett of the Detroit Free Press reports.

EDGE Analysis

Ragnow came out retirement this past Wednesday in an attempt to bolster the Lions' offensive line, but that comeback was short lived after he failed his physical due to a Grade 3 hamstring strain. He has been placed back on the reserve/retired list, and it remains to be seen whether the 29-year-old will attempt to come out of retirement again going into the 2026 season. Graham Glasgow (knee) will remain as Detroit's starting center while Trystan Colon serves as the backup.

The Lions announced Saturday that Ragnow failed his physical due to a Grade 3 hamstring strain, which will keep the 29-year-old sidelined for the 2025 season.

EDGE Analysis

The 2018 first-rounder came out of retirement Wednesday, and despite signs pointing to him being available as soon as Week 15 against the Rams, his physical came back with the diagnosis of a severe hamstring strain. Head coach Dan Campbell relayed to reporters Saturday that Ragnow disclosed to the team that he was dealing with a hamstring injury, but neither party knew its severity until the physical, per Colton Pouncy of The Athletic. With Ragnow out of the picture, Graham Glasgow (knee) will remain as the Lions' starting center while Trystan Colon -- who started against the Packers on Thursday -- serves as the backup.

The Lions reinstated Ragnow (undisclosed) from the reserve/retired list Wednesday.

EDGE Analysis

Ragnow announced his retirement from the NFL during the offseason, and despite missing training camp, Ian Rapoport of NFL Network relays that the veteran center is "in shape and ready to roll sooner, rather than later." Ragnow has since been placed on the exempt/commissioner permission list, and while he's eligible to play in Week 14 against the Cowboys, it's more likely that he'll be available to play in Week 15 against the Rams on Sunday, Dec. 14, per Adam Schefter of ESPN. Once he's cleared to play, Ragnow could reclaim his starting spot at center from Graham Glasgow (knee).

Ragnow announced his decision to retire from the NFL on Monday via his personal Instagram account.

EDGE Analysis

Ragnow's statement reads, in part: "I have given this team everything I have and I thought I had more to give, but the reality is I simply don't. I have to listen to my body and this has been one of the hardest decisions of my life." The 29-year-old has remained one of the NFL's best centers despite battling injuries in recent seasons, and coming off three consecutive Pro Bowl campaigns his retirement comes both as a shock, and as a notable blow for one of the NFC's best offenses. Ragnow's announcement comes just days after news of his holding out from voluntary workouts due to dissatisfaction with his current contract, per Christian Booher of SI.com. Starting guards Tate Ratledge and Graham Glasgow both have experience at center, so Detroit could rely on one of them to take over for Ragnow while asking 2024 sixth-rounder Christian Mahogany to step into a larger interior role after a solid rookie campaign.

Ragnow (pectoral) was listed as a full participant on Wednesday's practice estimation, Tim Twentyman of the Lions' official site reports.

EDGE Analysis

Ragnow's full practice estimation Wednesday is an indication that the 28-year-old offensive lineman is past the pectoral injury that held him out of the Lions' Week 4 win over the Seahawks. Now that Ragnow is at full health once again, he's expected to serve as Detroit's top center.

Coach Dan Campbell said Monday that Ragnow (pectoral) was back at practice, Tim Twentyman of the Lions' official site reports.

EDGE Analysis

Ragnow sat out of Detroit's contest in Week 4 with a pectoral issue before the Lions' Week 5 bye, but it now appears he may be on track to return to the field for Week 6. The Lions' first official practice report of the week Wednesday should give a better indication of Ragnow's status.

Lions head coach Dan Campbell said Thursday that Ragnow (pectoral) has been ruled out for Monday's game against the Seahawks, Tim Twentyman of the Lions' official site reports.

EDGE Analysis

Ragnow, who is tending to a partial pec tear, will sit out the Week 4 game and then benefit from a Week 5 bye, potentially allowing him to return to the field Week 6 versus the Cowboys on Oct. 13. Graham Glasgow will likely slide over from left guard to start at center until Ragnow is ready to go. Ragnow is a pillar of the Lions' offensive line, so the team should prioritize his long-term health above all else.

Ragnow is week-to-week after suffering a partial tear to his pec during Sunday's 20-13 win at Arizona, Ian Rapoport of NFL Network reports.

EDGE Analysis

Ragnow didn't miss a snap of the Lions' contest in Week 3 despite the injury, a testament to his ability to play through pain. Detroit may exercise some caution with their standout center, however, potentially creating an opening for backup Michael Niese to see some playing time.

Ragnow (ankle/knee/toe) plans to take time this offseason to assess his injuries and plot his future, Kyle Meinke of MLive.com reports.

EDGE Analysis

Ragnow has been dealing with an inoperable toe condition for the better part of three years and played through knee and ankle sprains during Detroit's playoff run. The 27-year-old just wrapped up his sixth NFL season after being drafted No. 20 overall in 2018 out of Arkansas. He missed just two starts in 2023, but injuries have clearly taken a toll on his body. "I need to find a way to get back to Frank," Ragnow said. "And I don't regret any of this at all, but it weighs on you, and I'm just going to take some time and really figure everything out to make sure that I'm feeling good, not only for me the football player but for me to be the best husband and best father and everything with that as well."

Ragnow (ankle/knee) has no injury designation ahead of Sunday's NFC Championship Game against the 49ers, Tim Twentyman of the Lions' official site reports.

EDGE Analysis

Despite being in visible pain throughout the Lions' divisional-round win over the Buccaneers, Ragnow was able to play through his injuries. He's expected to do it once again in the NFC Championship Game while filling his usual starting center role.