Deone Walker
IL/DT BUF (7)
Tue 2/3/26 1:35 PM

Walker logged 39 total tackles (17 solo), including 1.0 sacks, and four passes defensed across 17 regular-season games in 2025.
EDGE Analysis
The 2025 fourth-round pick from Kentucky was thrust into action immediately, starting 16 regular-season contests during his rookie campaign. Walker was the Bills' most productive interior defensive lineman, finishing second on the team in tackles for loss (eight) and tying for fourth in passes defensed. The 21-year-old showed up when it mattered most during Buffalo's two playoff games, recording six total tackles and two passes defensed, including an interception of Bo Nix during the divisional-round loss. Walker is expected to remain an integral portion of the Bills' defensive front for years to come.

Deone Walker
IL/DT BUF (7)
Sun 1/4/26 3:19 PM

Walker (illness) is active for Sunday's game against the Jets.
EDGE Analysis
Walker popped up on Saturday's injury report due to an illness, but the rookie fourth-rounder has been cleared to play in Sunday's regular-season finale. Even if the Bills opt to rest their starters, Walker could still take on a larger role on the defensive line in the absence of DaQuan Jones (calf).

Deone Walker
IL/DT BUF (7)
Sat 1/3/26 4:29 PM

Walker (illness) is listed as questionable ahead of Sunday's game against the Jets.
EDGE Analysis
Walker was added to Saturday's injury report due to a sudden illness, and the defensive tackle's availability for Sunday's game is now in jeopardy. If the rookie cannot recover in time for the divisional clash, Jordan Phillips (ankle), Phidarian Mathis and T.J. Sanders will likely see increased reps on the defensive line alongside Larry Ogunjobi.

Deone Walker
IL/DT BUF (7)
Sun 8/10/25 8:41 PM

Walker recorded one pass deflection during Saturday's 35-24 preseason loss to the Giants.
EDGE Analysis
Walker missed time due to illness leading up to Buffalo's preseason clash with New York, but he managed to get healthy in time to play. The rookie fourth-round pick is competing for depth rotational reps along the Bills' interior defensive line.

Deone Walker
IL/DT BUF (7)
Mon 8/4/25 11:53 AM

Walker (illness) isn't practicing Monday, Alaina Getzenberg of ESPN.com reports.
EDGE Analysis
Walker will look to recover in time to play in Saturday's preseason opener against the Giants. The rookie fourth-round pick out of Kentucky will likely begin his NFL career in a rotational role.

Deone Walker
IL/DT BUF (7)
Sat 5/10/25 11:37 AM

Walker, who is in rookie camp this week, revealed that he played the 2024 season with a back injury, Alec White and Maddy Glab of the Bills' official site report. "I had a pars defect in my back," Walker said on the night of the 2025 NFL Draft. "I didn't know about it until after the season, really until the combine. We didn't really know what it was, but I feel a 100 percent right now."
EDGE Analysis
Walker, selected in the fourth round, is a giant of a man at 6-foot-7, 331 pounds, and at some point during his college career at Kentucky he was expected to be drafted higher, as he was a lot more productive when healthier in 2023. He'll begin as a rotational defensive lineman among a talented crew that includes Greg Rousseau. Ed Oliver, Joey Bosa and DaQuan Jones, though Walker offers plenty of upside. Perhaps the Bills got themselves a steal now that the back issue is mostly behind him.