Amendola (knee) has been ruled out for Sunday's game against the Colts.

EDGE Analysis

Amendola sustained a meniscus injury during last week's loss to the Jets and was unable to practice ahead of Sunday's matchup. He's expected to miss up to four weeks, so the Texans could place the wide receiver on injured reserve to open up a spot on the active roster. Nico Collins, Chris Conley and Chris Moore could see an uptick in targets while Amendola is out.

Amendola suffered a knee injury during Sunday's loss to the Jets and could miss up to four weeks, Brooks Kubena of the Houston Chronicle reports.

EDGE Analysis

Amendola underwent an arthroscopic knee procedure Tuesday, but the Texans haven't yet offered up a firm timeline for his return. If the expected multi-week absence is confirmed, the 36-year-old slot receiver could head to injured reserve. Despite previously missing four contests due to a hamstring injury earlier this season, Amendola currently ranks tied for third on the Texans with 29 targets. Brandin Cooks could receive more looks, but he's already well established as the team's No 1 wideout. Further down the depth chart, rookie Nico Collins, who's averaged 4.2 targets over six games since returning from his own injury, could see additional targets. Houston also has veterans Chris Conley and Chris Moore rostered. Moore was signed to the active roster after Amendola suffered the hamstring injury and has remained on the roster since. He may be the primary replacement at slot receiver for Amendola.

Amendola caught three of five targets for 23 yards in Sunday's 21-14 loss to the Jets.

EDGE Analysis

Amendola finished fourth among Houston's wideouts with 22 snaps but had an equal number of targets as Brandin Cooks and Nico Collins, the Texans' top two receivers. One week after Amendola appeared to be headed for a reduced role, the 36-year-old was a key figure. Of course, that might not mean much in Houston's low-wattage passing attack, and Amendola's lone touchdown catch came back in Week 1.

Amendola did not catch his lone target and played 13 snaps in Sunday's 22-13 win over Tennessee.

EDGE Analysis

Amendola had the fewest number of snaps among Houston's five active wide receivers, which is a significant change. He had been among the top three in terms of playing time and targets prior to the team's bye last week. That suggests the 36-year-old Amendola will play a reduced role over the final weeks of the regular season, while Nico Collins, Chris Conley and Chris Moore receive added playing time.

Amendola caught three of seven targets for 49 yards in Sunday's 17-9 loss to the Dolphins.

EDGE Analysis

Amendola was second in targets behind Brandin Cooks and remains a key part of the offense, having gathered 17 targets in three games since returning from a thigh injury. The Texans have a bye in Week 10, which could be an opportunity to recalibrate the offense. To have the 36-year-old Amendola sucking up targets on a 1-8 team seems pointless.

Amendola caught two of five targets for three yards in Sunday's 38-22 loss to the Rams.

EDGE Analysis

In terms of production, Amendola's performance wasn't much, but he continues to have a significant role in the passing game when healthy. He was second among Houston wide receivers in targets and snaps. In two games since returning from a four-game absence due to a thigh injury, he's been targeted 10 times. That might be the Texans showcasing the 35-year-old receiver ahead of the trade deadline Nov. 2, the day on which he turns 36.

Amendola caught three of five targets for 17 yards and returned one kickoff for 15 yards in Sunday's 31-5 loss to the Cardinals.

EDGE Analysis

Amendola returned to action Sunday after missing four games due to a thigh injury. He fit in behind Brandin Cooks and Nico Collins in terms of snap count and shared third wideout duties with Chris Conley. Amendola's five targets tied for third with Collins, behind David Johnson (seven) and Cooks (six). He and Tremon Smith both were added to the return team Sunday, the first game following the Texans' decision to release Andre Roberts. Amendola has been targeted 11 times over 53 snaps, the best target-to-snap ratio among the wideouts, but his injury history works against him. Plus, he's a 35-year-old (36 on Nov. 2) playing for a 1-6 team that should eventually start evaluating all of its younger players in the pipeline.

Amendola (thigh) practiced fully Wednesday.

EDGE Analysis

Amendola is thus in line to return to action Sunday against the Cardinals and is in a position to reclaim a share of the Texans' slot duties in the process. In the two games he suited up for this season, Amendola caught all six of his targets for 43 yards and a TD. With rookie Davis Mills slated to start at QB at least one more game for Houston, Amendola profiles as a speculative Week 7 lineup option in deeper PPR formats while squaring off against 6-0 Arizona.

Amendola (thigh) is inactive Week 6 against the Colts.

EDGE Analysis

Amendola was able to log three practices on a limited basis this week, but that won't be enough for the 35-year-old to make his first appearance since Week 2. Look for Brandin Cooks, Chris Conley and Chris Moore to again lead the receiving corps in his stead, with a potential boost from the recently-activated Nico Collins.

Amendola (thigh) is listed as questionable for Sunday's game against the Colts.

EDGE Analysis

Amendola was limited in all three practice sessions this week, so it's hard to get a read on his availability, especially after he also practiced in a limited fashion last week prior to sitting out. If he's able to suit up Sunday, it will be Amendola's first action since Week 2.