Rams head coach Sean McVay said Kupp will undergo surgery Wednesday to address his right high-ankle sprain, and the receiver will be placed on injured reserve, Adam Schefter of ESPN reports.

EDGE Analysis

The Rams aren't yet willing to rule out the possibility of Kupp returning in Week 15 after the minimum four-game stint on IR, but with the team sitting on a 3-6 record and on the outside looking in for a playoff spot, there's a chance the star wideout's 2022 campaign is over. According to Jourdan Rodrigue of The Athletic, Kupp is having a "tightrope procedure," which typically carries a 4-to-8-week recovery timeline. With that in mind, even if the Rams find themselves in the playoff picture by late December/early January, the 29-year-old may not be ready to play before the end of the regular season. Even as the reigning Super Bowl champions struggled mightily over the first half of the season, Kupp remained productive with a 75-812-6 receiving line on 98 targets to go with 52 yards and another score on the ground through nine games. His absence creates a major void in the L.A. passing attack, with the likes of Allen Robinson, Van Jefferson, Ben Skowronek and Tyler Higbee all representing candidates to absorb some of Kupp's vacated target volume.

Kupp suffered a high-ankle sprain in Sunday's 27-17 loss to Arizona, and the prognosis "doesn't sound good," Adam Schefter of ESPN.com reports.

EDGE Analysis

There was some optimism around Kupp's injury after initial tests revealed that he avoided a fractured ankle, but further examination revealed ligament damage. While a return timetable for the star wide receiver has yet to be established, high-ankle sprains typically take 4-to-6 weeks to recover from, and the Rams can ill afford to lose Kupp for that long considering they're on the verge of falling out of the playoff race at 3-6.

Kupp's expected to miss some time, but he appears to have avoided the worst-case scenario with his ankle injury, Ian Rapoport of NFL Network reports.

EDGE Analysis

Kupp went to the locker room after getting hit in the fourth quarter of the Week 10 loss to Arizona. Coach Sean McVay initially feared a season-ending injury, and while Kupp won't be completely out of the woods until more test results come in, he appears to be dealing with a less severe injury. A return in Week 11 against New Orleans looks unlikely at first glance, but a clearer picture of Kupp's status should emerge after further testing.

Coach Sean McVay didn't have a post-game update on Kupp's (ankle) status after Sunday's 27-17 loss to the Cardinals, but he said the injury "didn't look good, didn't sound good," Jourdan Rodrigue of The Athletic reports.

EDGE Analysis

It's not clear if this injury is related to the ankle injury Kupp sustained in Week 8 against the 49ers, but he limped to the locker room in the fourth quarter of Sunday's loss to Arizona after taking a low hit. Further tests will have to be run before an update surfaces on the star receiver's status, but McVay's somber tone regarding the injury suggests Kupp could be in danger of sitting out against the Saints in Week 11 and possibly beyond.

Kupp (ankle) went to the locker room early in the fourth quarter of Sunday's game against the Cardinals, Gary Klein of the Los Angeles Times reports.

EDGE Analysis

Kupp incurred a low hit from Arizona cornerback Marco Wilson and was seen holding his right leg after the play. After receiving medical attention, he was hobbled going to the sideline, where he was looked at by team trainers before limping to the locker room. Officially doubtful to return, Kupp likely will finish Week 10 action with three catches for minus-1 yard on five targets.

Kupp caught eight of nine targets for 127 yards and a touchdown in Sunday's 16-13 loss to the Buccaneers.

EDGE Analysis

The All-Pro wideout accounted for an incredible 77 percent of Matthew Stafford's passing yards on a day in which no other Ram has any success at all on offense. Kupp has topped 100 receiving yards in five of eight games this season while hauling in six TD catches and adding one more on the ground, and he seems just about matchup-proof heading into a Week 10 clash with the Cardinals.

Kupp (ankle) doesn't have an injury designation for Sunday's game in Tampa Bay, Greg Auman of The Athletic reports.

EDGE Analysis

Fellow wide receiver Van Jefferson (knee) is listed as questionable, but with coach Sean McVay saying he's optimistic Jefferson will play. Kupp's availability is far more important to the Rams offense, of course, and he'll avoid missed time after hurting his ankle deep in garbage time of the Week 8 loss to San Francisco. The Bucs haven't maintained their hot start to the season on the defensive side of the ball, but that's partially due to injuries -- something that may soon be less of a factor with CBs Carlton Davis (hip) and Sean Murphy-Bunting (quad) listed as questionable after missing the past few weeks. Kupp was a full practice participant Friday and should see plenty of targets this Sunday.

Kupp (ankle) practiced on a limited basis Thursday, Sarah Barshop of ESPN.com reports.

EDGE Analysis

After sitting out Wednesday's session, Kupp was expected to get back on the field Thursday with a cap on his reps, which came to pass. He may continue to operate with practice limitations this week after having his right ankle rolled up near the end of this past Sunday's loss to the 49ers. Friday's injury report ultimately will reveal whether or not Kupp enters the weekend with a designation for Sunday's road matchup with the Buccaneers.

Kupp (ankle) was present at the portion of Thursday's practice open to the media, Gilbert Manzano of The Orange County Register reports.

EDGE Analysis

The Rams are taking it easy on Kupp after he hurt his right ankle in the waning minutes of a Week 8 loss to the 49ers. He didn't practice at all Wednesday, but coach Sean McVay said Kupp is expected to be a limited participant for the rest of Week 9 prep. Thursday's injury report may confirm as much.

Kupp (ankle) will be a non-participant at Wednesday's practice, Jourdan Rodrigue of The Athletic reports.

EDGE Analysis

On his last touch of this past Sunday's loss to the 49ers, Kupp's right ankle bent awkwardly as he was tackled to the ground. He eventually was diagnosed with a sprained ankle, with head coach Sean McVay telling Rodrigue on Monday that the wide receiver avoided structural damage but has some swelling in the affected region. Despite not practicing Wednesday, Kupp is expected to be able to play Sunday at Tampa Bay, so he's a decent bet to get back on the field Thursday and/or Friday.