McCaffrey (knee) was limited at Thursday's practice, Eric Branch of the San Francisco Chronicle reports.

EDGE Analysis

The 49ers continue to place practice restrictions on McCaffrey, who has been listed on the team's injury report with a knee issue for five weeks in a row. Friday's report will clarify whether or not he enters the weekend with a designation ahead of Sunday's game at Las Vegas, but the aforementioned health concern hasn't stopped him from producing each of the last four contests, a span in which he's averaged 22.5 touches for 123.8 yards from scrimmage per game while scoring five touchdowns.

McCaffrey (knee) will be a limited practice participant Wednesday, Jennifer Lee Chan of NBC Sports Bay Area reports.

EDGE Analysis

Despite tending to a knee issue each of the previous four weeks of practice, McCaffrey has been producing on game days, recording 90 touches for 495 yards from scrimmage and five TDs over the last four contests. He managed just 58 total yards on 17 touches this past Saturday against the Commanders, but he salvaged his Week 16 with a one-yard touchdown late in the fourth quarter. While McCaffrey may have a cap on his reps during the entirety of Week 17 prep, there's a good chance he'll sidestep a designation ahead of Sunday's game in Las Vegas.

McCaffrey rushed 15 times for 46 yards and a touchdown while chipping in two receptions for 12 yards in Saturday's 37-20 win over Washington.

EDGE Analysis

McCaffrey struggled to find running room against a stout Washington defense that welcomed back star defensive lineman Chase Young on Saturday. The dual-threat back salvaged what would have been a lackluster fantasy day by punching in a one-yard touchdown late in the fourth quarter to ice the win for his club. Perhaps the lowered usage was by design after the oft-injured back carried the offense against Seattle with 32 combined touches in Week 15. A well-rested McCaffrey could be primed to go off against a generous Raiders defense next Sunday.

McCaffrey (knee) doesn't have a designation for Saturday's contest against the Commanders, Nick Wagoner of ESPN.com reports.

EDGE Analysis

McCaffrey has been operating under practice limitations for four weeks running, but his knee issue won't stop him from suiting up for yet another game day. He's been absolutely dialed in over the last three outings, averaging 24.3 touches for 145.7 yards from scrimmage per game while tallying four total TDs. McCaffrey will be aiming to keep up the hot stretch versus Washington's 12th-ranked run defense (111.6 yards per game).

McCaffrey (knee) practiced in a limited fashion Wednesday, Nick Wagoner of ESPN.com reports.

EDGE Analysis

For a fourth week in a row, McCaffrey is enduring practice limitations due to a listed knee issue, but it hasn't stopped him from producing on game days. Over the last three contests, he's averaged 24.3 touches for 145.7 yards from scrimmage per game while recording four total touchdowns. Assuming he gains clearance to play Saturday against the Commanders, McCaffrey will be looking for a fourth consecutive performance with at last 138 total yards and one score.

McCaffrey (knee) will be a limited practice participant Tuesday, Cam Inman of The San Jose Mercury News reports.

EDGE Analysis

Coming out of their Week 15 win over the Seahawks on Thursday, the 49ers haven't indicated that McCaffrey suffered any setbacks with the knee issue that first cropped up following the team's Week 12 win over the Saints, so the running back's limitations to begin Week 16 prep are most likely a matter of maintenance. In the three games since the injury surfaced, McCaffrey has played more than two-thirds of the snaps on offense each time while averaging 19 carries and seven targets per contest. Another heavy snap count and touch count should await McCaffrey in Saturday's game against the Commanders.

McCaffrey rushed 26 times for 108 yards and a touchdown while bringing in six of eight targets for 30 yards in the 49ers' 21-13 win over the Seahawks on Thursday night.

EDGE Analysis

McCaffrey filled a true workhouse role for the first time as a 49er, logging a season high in carries along the way. The star back scored his second rushing touchdown in as many games when he went in from one yard out late in the first half following a Travis Homer fumble and 40-yard return by Charvarius Ward. McCaffrey now has back-to-back 100-yard efforts as well going into a Week 16 home matchup versus the Commanders a week from Saturday.

McCaffrey (knee) doesn't have an injury designation for Thursday's game against Seattle, Jennifer Lee Chan of NBC Sports Bay Area reports.

EDGE Analysis

McCaffrey has been playing through the knee injury for weeks now, and while head coach Kyle Shanahan has been cautious with the running back's usage in the second half of games while leading by multiple scores, the 49ers have otherwise unleashed McCaffrey to full effect. He played 98 percent of the offensive snaps in the first half of Sunday's 35-7 win over the Buccaneers, finishing with 153 yards and two touchdowns despite playing only 18 percent of the snaps post-halftime. There's little doubt McCaffrey will be featured again Thursday as the 49ers look to clinch the NFC West crown.

McCaffrey (knee) was a limited participant in Tuesday's walk-through practice, James Palmer of NFL Network reports.

EDGE Analysis

McCaffrey appeared on the 49ers' practice report as a limited participant for the second day in a row, but head coach Kyle Shanahan hasn't suggested that the knee irritation the running back has been managing for more than two weeks is anything that will cost him game action. With a quick turnaround for Thursday's matchup with Seattle after he took 16 touches in this past Sunday's 35-7 win over the Buccaneers, McCaffrey is likely just getting some extra maintenance in practice to keep him as fresh as possible for the Week 15 contest.

McCaffrey (knee) was listed as limited on Monday's practice estimate, Nick Wagoner of ESPN.com reports.

EDGE Analysis

McCaffrey logged 44 of a possible 63 snaps on offense in Sunday's 35-7 win over the Buccaneers en route to carrying 14 times for 119 yards and a TD while adding two catches (on three targets) for 34 yards and a receiving score. With no reported setbacks in that contest, it seems likely that the running back's listed limitations Monday are maintenance-related rather than indicative of any setbacks with the knee issue he's managed at practice of late.