Clay caught three of five targets for 14 yards during Sunday's 37-5 loss to Indianapolis.

EDGE Analysis

Clay has now been held to 20 or fewer yards five time this season and has yet to top 40 yards or score in a game. Buffalo's entire offense has been plagued with inexperience, ineffectiveness or both at the quarterback position. In theory, Sunday's matchup against New England's bottom-10 pass defense could be an opportunity for Clay, but that would require placing a modicum of faith in Derek Anderson's right arm.

Clay caught four of five targets for 20 yards in Sunday's loss to the Texans.

EDGE Analysis

Clay, who is frequently banged up and misses occasional practice time, has been relatively healthy lately but the squirt gun Buffalo offense just can't get anyone going. Clay still hasn't seen the end-zone turf and has a season high of 40 yards. He's deep down the list of fantasy options, even though he sees clear-cut starter's time on the field.

Clay, who was rested Thursday, does not carry a Week 6 injury designation.

EDGE Analysis

The tight end is thus good to go Sunday against the Texans, but his early fantasy returns this season have been modest. Through five games to date, Clay has yet to score a TD and still hasn't topped 40 receiving yards. Overall, he's hauled in nine of his 15 targets for 99 yards in that span.

Clay did not practice Thursday but the reason given was a veteran rest day, Chris Brown of the Bills' official site reports.

EDGE Analysis

Clay's production has also taken a rest this season, as the tight end is still looking for his first score and hasn't gone over 40 yards in any game. If the Bills' reason for his absence is accurate, we'd expect him back in a full capacity Friday ahead of Sunday's game in Houston.

Clay, who missed practice time with an ankle injury last week, played 75 percent of the offensive snaps and caught his only target for 12 yards.

EDGE Analysis

The Bills only completed 10 passes on the day so it's not like anyone else was taking over the passing game. However, Clay has been held to 40 yards or less in all five games this season and has yet to find the end zone. You can safely keep him on the waiver wire until the Buffalo offense starts proving to be more productive. That may take awhile, as the team sadly hasn't put up 300 yards of total offense in any game this season.

Clay (ankle) is active for Sunday's game against the Titans.

EDGE Analysis

Clay was limited at Wednesday's practice and sat out entirely the following day, but he is good to go for Week 5 on the heels of a full session Friday. Clay will square off against a Titans defense that surrendered 12 receptions and 125 yards to Eagles tight ends last week, but has not allowed opposing tight ends to find paydirt all season.

Clay (ankle) is listed as questionablee for Sunday's game against the Titans after being listed as a full practice participant Friday.

EDGE Analysis

Previous reports suggested that the tight end probably wouldn't work Friday, but the Bills' final injury report of the week brightens Clay's Week 5 playing prospects. Officially confirmation of his status will arrive in advance of Sunday's 1:00 ET kickoff, but even if Clay plays this weekend, his fantasy ceiling appears modest. On the plus side, he is coming off his best game of the season, having hauled in four of his six targets for 40 yards in last Sunday's 22-0 loss to the Packers.

Clay (ankle) is not in line to practice Friday, Chris Brown of the Bills' official site reports.

EDGE Analysis

With Clay trending in the wrong direction as Sunday's game against the Titans approaches, it looks like Jason Croom and Khari Lee will probably head the Bills' Week 5 tight end corps.

Clay (ankle) did not practice Thursday after being limited Wednesday, Chris Brown of the Bills' official site reports.

EDGE Analysis

Clay often plays after sitting out a chunk of the practice week, but the fact he apparently couldn't go at all Thursday leaves him sketchy for this week's game against the Titans. He's coming off his only good game of the season with a four-catch, 40-yard outing in Sunday's loss to the Packers, though he's still looking for his first score a quarter of the way through the season.

Clay (ankle) was limited at Wednesday's practice.

EDGE Analysis

Clay is no stranger to the injury report, so we suspect that he'll be able to play through his ankle issues Sunday against the Titans. His 40 yards (via four catches) in Week 4's 22-0 loss to the Packers actually paced the Bills, but overall Clay has logged just eight catches (on 14 targets) for 87 yards one quarter into the 2018 season. Looking ahead, it's possible that the veteran tight end will emerge as a reliable target for rookie QB Josh Allen, but we need to see that become a pattern before endorsing Clay as a fantasy lineup option.