The Cardinals placed Knight (ankle) on injured reserve Tuesday, Zach Gershman of the team's official site reports.

EDGE Analysis

Knight played just one snap in this past Sunday's 40-20 loss to the Texans before exiting the contest with a left ankle sprain. While follow-up tests revealed no structural damage to Knight's ankle, his sprain is significant enough to sideline him for the final three games of the season. With Knight joining James Conner (foot) and Trey Benson (knee) on injured reserve, Arizona will be left with Michael Carter and Emari Demercado as its primary backfield options for the remainder of the campaign. Knight will be a restricted free agent this offseason after he carried 82 times for 269 yards (3.3 YPC) and four touchdowns to go with 160 yards and another score on 22 catches over 12 appearances for Arizona.

Knight (ankle) is set for an MRI after being carted off the field during Sunday's 40-20 loss to Houston, but he's believed to be dealing with a sprain, Adam Schefter of ESPN reports.

EDGE Analysis

Knight appears to have avoided a severe injury, with league sources telling Schefter that the running back is nursing "a bad sprain," but that could still notably impact his availability for the last three weeks of the regular season. Emari Demercado and Michael Carter will be positioned as Arizona's clear backfield leaders if Knight misses any time, with James Conner (foot) and Trey Benson (knee) both already having been lost for the year. Knight's first opportunity to attempt to prove he's healthy enough to play Week 16 against the Falcons will come during Wednesday's practice.

Knight (ankle) has been ruled out for the remainder of Sunday's game versus the Texans.

EDGE Analysis

Knight logged just one carry for minus-2 yards before exiting and being carted to he locker room in the first quarter. The 24-year-old has been serving as the Cardinals' top running back with James Conner (foot) and Trey Benson (knee) both out for the season. Over the last eight games prior to Week 15, Knight recorded 77 rushes for 260 yards and three touchdowns to go along with 21 catches (on 30 targets). His next opportunity to take the field will come Week 16 versus the Falcons on Sunday, Dec. 21. In Knight's absence, Emari Demercado and Michael Carter will carry the load at running back.

Knight exited Sunday's game at Houston due to an ankle injury, Darren Urban of the Cardinals' official site reports.

EDGE Analysis

Knight had his left ankle pinned under a Texans defender as he was tackled to the turf early in the first quarter. Per Urban, Knight was carted to the locker room and soon after was deemed questionable to return. Michael Carter and Emari Demercado are left as the likeliest candidates to carry Arizona's backfield for as long as Knight is sidelined.

Knight was held to 16 yards on seven carries while catching three of six targets for 18 yards in Sunday's 45-17 loss to the Rams.

EDGE Analysis

Knight failed to take advantage of lead-back duties with both Trey Benson (knee) and Emari Demercado (ankle) still missing Sunday. The 24-year-old Knight struggled to generate much running room early on, then fell victim to the blowout game script in the second half. The journeyman backup failed to mask his poor production with a trip to the end zone like we saw in Weeks 11 and 12. With the aforementioned teammates potentially nearing returns, Knight's brief run of fantasy utility could come to a close in short order, assuming it hasn't run dry already.

Knight rushed 11 times for 62 yards and brought in all three targets for 36 yards and a touchdown in the Cardinals' 20-17 loss to the Buccaneers on Sunday.

EDGE Analysis

Knight was the clear lead back with Emari Demercado (ankle) sidelined, and the journeyman put together a season-high yardage total while logging double-digit carries for the second straight game and fifth time in the last seven contests overall. Knight also averaged a season-high 5.6 yards per carry, and he recorded the first receiving touchdown of his career on a 15-yard grab during a broken play late in the third quarter. Despite the encouraging performance, Knight's role could be diminished significantly in a Week 14 home matchup against the Rams if Trey Benson (knee) returns from injured reserve.

Knight (knee) is listed as active Sunday in Tampa Bay.

EDGE Analysis

Knight has battled lower-body injuries at times over the last month and a half, with a knee issue limiting him at all three Week 13 sessions and leaving him questionable for Sunday's contest. Now that he's confirmed to be available, he appears poised to get a majority share of the Cardinals' backfield reps considering Trey Benson (knee) remains on injured reserve and Emari Demercado is sitting out a second straight game due to a high-ankle sprain. Over the last five outings with various RB personnel available for Arizona, Knight has tallied 221 yards from scrimmage and two rushing TDs on 62 touches. Michael Carter is Knight's greatest threat to take on snaps.

Knight, who is officially questionable to play Sunday against the Buccaneers due to a knee injury, is expected to suit up, Adam Schefter of ESPN reports.

EDGE Analysis

Knight was limited in all three practices this week while managing a knee issue. He was deemed questionable to suit up on Friday's final injury report, but it sounds like he's going to give it a go against Tampa Bay. Trey Benson (knee) and Emari Demercado (ankle) have both been ruled out for the contest, so Knight should serve as Arizona's top RB, though Michael Carter should get a fair amount of offensive snaps as well.

Knight (knee) is listed as questionable for Sunday's game at Tampa Bay, Bo Brack of GoPHNX.com reports.

EDGE Analysis

With Trey Benson (knee) and Emari Demercado (ankle) ruled out for Week 13, Knight now is the only question mark among the Cardinals' running backs that are dealing with injuries. Knight's knee issue limited him in all three practices this week, and his status will be clarified about 90 minutes before Sunday's 1:00 p.m. ET kickoff. Assuming he's able to suit up this weekend, he and Michael Carter likely will split the backfield reps in some fashion, but Jermar Jefferson also may be on hand for his first touch of the season.

Knight (knee) was listed as limited on Thursday's injury report, Josh Weinfuss of ESPN.com reports.

EDGE Analysis

Meanwhile, Trey Benson (knee), who remains on injured reserve, and Emari Demercado (ankle) were listed as non-participants, leaving Knight and Michael Carter as the healthiest of the Cardinals' top options at running back at the moment. Friday's practice report will reveal who among the quartet has a chance to suit up Sunday at Tampa Bay.