Recent tests showed Manning to be dealing with fatigue and tendinitis in his arm, Jason Beck of MLB.com reports.

EDGE Analysis

Manning's injury this late in the season virtually guarantees he will not pitch again this year. The 24-year-old righty will finish the season with a 2-3 record alongside a 3.43 ERA and 1.17 WHIP over 63 innings.

Manning experienced some fatigue in his arm while warming up for his scheduled start Wednesday against Kansas City.

EDGE Analysis

The nature of Manning's injury is now confirmed, and the decision to scratch him from Wednesday's game was made as a precaution. Further details will be provided once the Tigers are able to evaluate him after the game.

Manning didn't start as expected Wednesday against the Royals, as Will Vest instead took the mound for the Tigers, Cody Stavenhagen of The Athletic reports.

EDGE Analysis

Manning was confirmed as Wednesday's starter and went through his usual pregame work, but he didn't take the mound for the opening frame. It's unclear if the 24-year-old is dealing with some sort of injury, but Detroit should update his status in the near future.

Manning (2-3) took the loss Wednesday, allowing five runs (three earned) on four hits and five walks over 5.1 innings against the Orioles. He struck out four.

EDGE Analysis

For just the second time this season, Manning allowed more walks than strikeouts as he never found his groove and suffered his third loss of the season. The five walks he allowed tied the most he's allowed in a single start in his young career. Manning still owns a 3.43 ERA and 1.17 and will try to get back on track in his next start, which figures to come against the Royals next week.

Manning allowed three hits over seven scoreless frames against the White Sox on Friday. He struck out five and did not factor in the decision.

EDGE Analysis

Detroit earned the win after 10 innings, preventing Manning from improving to 3-2. He never found himself in much danger during the dominant outing and, at one point, he retired 16 of 17 batters. The 24-year-old righty is now sporting a 3.28 ERA with a 44:14 K:BB through 57.2 frames. Manning is expected to start in Baltimore next week.

Manning (2-2) earned the win against the Royals on Saturday, allowing three runs (two earned) on three hits while striking out four and walking one over 6.1 innings.

EDGE Analysis

Manning tossed 60 of 94 pitches for strikes across 6.1 frames. He allowed two earned runs, one on a single in the first inning and another on a groundout in the fourth. He was not credited with a third earned run after an error during a fielder's choice allowed Michael Taylor to score. Manning has pitched relatively well in his last five games, aside from a seven-run clunker against Seattle. He has picked up three quality starts during that span. He will take a 3.73 ERA into his next outing.

Manning allowed two runs on five hits, three walks and a hit batsman while striking out three over four innings in a 3-2 loss Sunday against Kansas City. He did not factor into the decision.

EDGE Analysis

Manning scattered three hits and a walk over the first three innings as he held the Royals scoreless. In the fourth, two singles, two walks and a hit batsman led to two runs as he threw 33 pitches in the inning, bringing his total for the four innings up to 90. Since returning from a shoulder injury at the beginning of August, he's posted a 4.21 ERA, 1.43 WHIP and 31:13 K:BB in 36.1 innings across seven starts. His next start will likely be next weekend in Kansas City.

Manning (1-2) allowed seven runs on seven hits across 2.1 innings to take the loss Tuesday against the Mariners. He walked one and struck out one.

EDGE Analysis

After tossing six scoreless innings in his last start to earn his first win of the year, Manning regressed Tuesday. Two home runs helped do in the righty as Seattle scored six times in the third to break the game open. Manning now has a 3.79 ERA across 40.1 innings this season, and while the 24-year-old has shown flashes, he's still looking for more consistency at the MLB level. He'll look to bounce back in his next scheduled start Sunday against the Royals.

Manning (1-1) tossed six scoreless innings to earn the win Wednesday against the Giants. He allowed five hits and no walks, while striking out eight.

EDGE Analysis

Making just his seventh start of the season, Manning looked sharp, and he's now allowed just one run across 13 innings in his last two appearances. The righty has a nice 2.37 ERA in his limited work this season, and he could be setting himself up for a breakout 2023 campaign if he can put his injury issues behind him and fully tap into the potential that made him a top prospect a few years ago. Manning will look to keep rolling in his next scheduled start Tuesday against the Mariners.

Manning (0-1) took the loss to the Angels on Friday, allowing one run on three hits while striking out six and walking one over seven innings.

EDGE Analysis

The lone home run that Manning allowed to Jared Walsh in the second inning turned out to be the only run of the game, giving Manning the loss despite a strong outing. He threw 63 of 90 pitches for strikes and earned a seven-inning quality start. It was the third quality start in six games this season for the righty. Manning will take a 2.81 ERA through 31 innings into his next outing.