Santana is absent from the lineup for Wednesday's game versus the Brewers.

EDGE Analysis

Santana will get a routine day off after starting in each of the previous 11 contests. Kyle Manzardo will play first base for the Guardians on Wednesday.

Santana went 1-for-5 with a double, three RBI and a run scored in Wednesday's 8-6 win over the Nationals.

EDGE Analysis

The Guardians were held in check for the first five innings, but they eventually solved Washington starter Michael Soroka the third time through the lineup. Cleveland scored all eight of its runs in the sixth inning, when Santana kicked off the scoring with a three-run double. It was the second straight game with three RBI for Santana, who has driven home nine over the last six contests.

Santana went 4-for-9 with a walk, a home run, three RBI and four runs scored across both games of Tuesday's doubleheader split with the Nationals.

EDGE Analysis

The 39-year-old was productive in both contests, rattling off three singles and scoring twice in the matinee before launching a three-run homer off Brad Lord in the sixth inning of the nightcap. Santana is slashing .236/.329/.350 through 34 games this season with four homers, two steals, 13 RBI and 18 runs.

Santana went 2-for-4 with a solo home run and and RBI single in Friday's 5-3 loss to Toronto.

EDGE Analysis

Santana put the Guardians on the board in the second inning on a solo home run off Chris Bassitt, and the former tied things up at 3-3 in the eighth after his single to right field brought Daniel Schneemann home. Santana is up to three home runs on the season, though his last one before Friday was April 9 against the White Sox. He's slashing .229/.306/.330 with two stolen bases, 13 runs scored and nine RBI in 124 plate appearances this season.

Santana is out of the lineup for Thursday's game against the Twins.

EDGE Analysis

The Guardians will give Santana a breather for the day game after he started in each of the last four contests while going 4-for-11 with two walks, a stolen base and a run scored. Kyle Manzardo will fill in for Santana at first base.

Santana went 2-for-3 in Monday's 11-1 loss to Minnesota.

EDGE Analysis

Santana snapped a hitless run during Sunday's contest and followed up Monday with his first multi-hit effort in 10 games. He's batting .220 with a .598 OPS through 114 plate appearances.

Santana went 0-for-1 with a walk and an RBI in the first game of Saturday's doubleheader against Boston. He did not play in the nightcap.

EDGE Analysis

Santana produced a run with a sacrifice fly during Cleveland's four-run first inning, just his second RBI over the last 12 games. His batting average has dipped to .202 following a stretch of 23 at-bats without a hit.

Santana went 1-for-4 with a solo home run in Wednesday's 3-2 win over the White Sox.

EDGE Analysis

Santana took Sean Burke deep to center field for a 410-foot solo home run, which turned out to be the deciding run in Wednesday's game. Santana is off to a good start in 2025, and over his last eight outings he's gone 10-for-30 with three walks, four runs, two home runs and three RBI.

Santana went 2-for-3 with a solo home run, an additional run, an additional RBI and a walk against the Angels in Saturday's 10-4 loss.

EDGE Analysis

Santana knocked in half of Cleveland's runs in the contest, launching a solo homer to center field in the first inning and adding an RBI groundout in the third. The veteran first baseman has been a steady presence in the Guardians' lineup this season, as he's gotten at least one hit in six of his eight games and is slashing a sturdy .290/.343/.452 through 35 plate appearances.

Santana started at first base and went 2-for-4 with a double in Monday's 7-2 loss to San Diego.

EDGE Analysis

Santana has started at first base and served as Cleveland's cleanup hitter for all four games thus far. He's hit safely in three of those four games, going 6-for-16 with two doubles, three runs scored and one RBI. The 38-year-old (turns 39 on April 8) is projected to have an everyday role for the Guardians.