| Team | Game | Time | Description | Score |
|---|
| Cubs | BAL@BOS | Top 1 | Trey Mancini Single, pitcher Chris Sale | -1-0 |
| Cubs | BAL@BOS | Top 1 | Craig Gentry Strikeout, pitcher Chris Sale | 1-0 |
| Cubs | BAL@BOS | Top 1 | Manny Machado 1-Run Double, Trey Mancini scores, pitcher Chris Sale | 0-0 |
| Cubs | BAL@BOS | Top 1 | Adam Jones Out Mitch Moreland, Brock Holt, Manny Machado to 3rd, pitcher Chris Sale | 1-0 |
| Cubs | BAL@BOS | Top 1 | Danny Valencia Out Mitch Moreland, Tzu-Wei Lin, pitcher Chris Sale | 2-0 |
| Cubs | BAL@BOS | Top 2 | Chris Davis Strikeout, pitcher Chris Sale | 4-0 |
| Cubs | BAL@BOS | Top 2 | Tim Beckham Out Andrew Benintendi, pitcher Chris Sale | 5-0 |
| Cubs | BAL@BOS | Top 2 | Anthony Santander Strikeout, pitcher Chris Sale | 7-0 |
| Cubs | BAL@BOS | Top 3 | Caleb Joseph Strikeout, pitcher Chris Sale | 9-0 |
| Cubs | BAL@BOS | Top 3 | Trey Mancini Out Mitch Moreland, pitcher Chris Sale | 10-0 |
| Cubs | BAL@BOS | Top 3 | Craig Gentry Walk, pitcher Chris Sale | 9-0 |
| Cubs | BAL@BOS | Top 3 | Manny Machado Out Tzu-Wei Lin, pitcher Chris Sale | 10-0 |
| Cubs | BAL@BOS | Top 4 | Adam Jones Strikeout, pitcher Chris Sale | 12-0 |
| Cubs | BAL@BOS | Top 4 | Danny Valencia Walk, pitcher Chris Sale | 11-0 |
| Cubs | BAL@BOS | Top 4 | Chris Davis Strikeout, pitcher Chris Sale | 13-0 |
| Cubs | BAL@BOS | Top 4 | Tim Beckham Out Christian Vázquez, pitcher Chris Sale | 14-0 |
| Cubs | BAL@BOS | Top 5 | Anthony Santander Out Christian Vázquez, pitcher Chris Sale | 15-0 |
| Cubs | BAL@BOS | Top 5 | Caleb Joseph Out Mitch Moreland, Rafael Devers, pitcher Chris Sale | 16-0 |
| Cubs | BAL@BOS | Top 5 | Trey Mancini Out Mitch Moreland, Chris Sale, pitcher Chris Sale | 17-0 |
| Cubs | MIL@NYM | Top 1 | Lorenzo Cain Walk, pitcher Noah Syndergaard | 18-0 |
| Cubs | STL@CIN | Bot 1 | Billy Hamilton Strikeout, pitcher Carlos Martínez | 20-0 |
| Cubs | STL@CIN | Bot 1 | José Peraza Double, pitcher Carlos Martínez | 19-0 |
| No Choice | STL@CIN | Bot 1 | Joey Votto Walk, pitcher Carlos Martínez | 18-1 |
| Cubs | STL@CIN | Bot 1 | Adam Duvall Out, pitcher Carlos Martínez | 19-1 |
| Cubs | STL@CIN | Bot 2 | Tucker Barnhart Walk, pitcher Carlos Martínez | 18-1 |
| Cubs | STL@CIN | Bot 2 | Alex Blandino Out Tommy Pham, pitcher Carlos Martínez | 19-1 |
| Cubs | STL@CIN | Bot 2 | Phillip Ervin Out Yadier Molina, pitcher Carlos Martínez | 20-1 |
| Cubs | STL@CIN | Bot 2 | Homer Bailey Strikeout, pitcher Carlos Martínez | 22-1 |
| Cubs | STL@CIN | Bot 3 | Billy Hamilton Out José Martínez, pitcher Carlos Martínez | 23-1 |
| Cubs | STL@CIN | Bot 3 | José Peraza Walk, pitcher Carlos Martínez | 22-1 |
| No Choice | STL@CIN | Bot 3 | Joey Votto Out Yadier Molina, pitcher Carlos Martínez | 23-1 |
| Cubs | STL@CIN | Bot 3 | Scooter Gennett Strikeout, pitcher Carlos Martínez | 25-1 |
| Cubs | MIL@NYM | Top 4 | Lorenzo Cain Strikeout, pitcher Noah Syndergaard | 24-1 |
| Cubs | STL@CIN | Bot 4 | Adam Duvall Double, pitcher Carlos Martínez | 23-1 |
| Cubs | STL@CIN | Bot 4 | Tucker Barnhart Walk, pitcher Carlos Martínez | 22-1 |
| Cubs | STL@CIN | Bot 4 | Alex Blandino Out José Martínez, Kolten Wong, Adam Duvall to 3rd, pitcher Carlos Martínez | 23-1 |
| Cubs | STL@CIN | Bot 4 | Phillip Ervin Out Yadier Molina, pitcher Carlos Martínez | 24-1 |
| Cubs | STL@CIN | Bot 5 | Homer Bailey Strikeout, pitcher Carlos Martínez | 26-1 |
| Cubs | STL@CIN | Bot 5 | Billy Hamilton Out Yadier Molina, pitcher Carlos Martínez | 27-1 |
| Cubs | STL@CIN | Bot 5 | José Peraza Strikeout, pitcher Carlos Martínez | 29-1 |
| Cubs | MIL@NYM | Top 6 | Lorenzo Cain Walk, Jesús Aguilar to 2nd, pitcher Robert Gsellman | 30-1 |
| Cubs | MIL@NYM | Top 6 | Hernán Pérez 2-Run Error, Domingo Santana to 2nd, Lorenzo Cain scores, Jesús Aguilar scores, pitcher Robert Gsellman | 32-1 |
| No Choice | STL@CIN | Bot 6 | Joey Votto Out Carlos Martínez, José Martínez, pitcher Carlos Martínez | 33-1 |
| Cubs | STL@CIN | Bot 6 | Scooter Gennett Strikeout, pitcher Carlos Martínez | 35-1 |
| Cubs | STL@CIN | Bot 6 | Adam Duvall Out Tommy Pham, pitcher Carlos Martínez | 36-1 |
| Cubs | MIL@NYM | Top 7 | Lorenzo Cain Walk, pitcher AJ Ramos | 37-1 |
| Cubs | STL@CIN | Bot 7 | Tucker Barnhart Out José Martínez, Carlos Martínez, pitcher Carlos Martínez | 38-1 |
| Cubs | STL@CIN | Bot 7 | Alex Blandino Out Tommy Pham, pitcher Carlos Martínez | 39-1 |
| Cubs | STL@CIN | Bot 7 | Phil Gosselin Out Yadier Molina, pitcher Carlos Martínez | 40-1 |
| No Choice | COL@WSH | Top 2 | Ian Desmond Strikeout, pitcher Stephen Strasburg | 40-0 |
| No Choice | COL@WSH | Top 9 | Ian Desmond 1-Run Home Run, pitcher Sean Doolittle | 40-7 |
| No Choice | OAK@SEA | Bot 9 | Nelson Cruz Strikeout, pitcher Blake Treinen | 40-6 |
| No Choice | TEX@HOU | Top 4 | Adrián Béltre Walk, pitcher Justin Verlander | 40-7 |
| | | Bonuses & Miscellaneous | 46-7 |