Karlsson (undisclosed) will not suit up against the Rangers on Saturday, Steve Lloyd of TSN reports.

EDGE Analysis

Karlsson will miss his fourth game out of the Sens' last six and should probably be considered questionable at best for the regular season finale versus the Isles on Sunday. When healthy, the blueliner has been capitalizing on his opportunities as he has notched 16 points in his last 15 contests, including two goals and five assists with the man advantage. The Professional Hockey Writers' Association will likely be deciding between Karlsson and San Jose's Brent Burns when voting for the Norris Trophy -- awarded to the league's best defenseman.