| Team | | Time | Down | Distance | Pos | Description | Score | Max Pts |
|---|
| CHI | 4th | 1:56 | | | SF 35 | Jakeem Grant 27 yard Kick Return Attempt JaMycal Hasty | 33-22 | |
| SF | 4th | 3:14 | 2nd | 12 | CHI 15 | Elijah Mitchell Rushing Attempt DeAndre Houston-Carson | 30-22 | |
| SF | 4th | 4:31 | 4th | 24 | CHI 26 | Brandon Aiyuk 7 yard Punt Return Attempt J.P. Holtz, Christian Jones | 30-22 | |
| CHI | 4th | 5:12 | 2nd | 10 | CHI 40 | Justin Fields Incomplete Pass to Darnell Mooney | 30-22 | |
| CHI | 4th | 5:53 | 1st | 10 | CHI 40 | Khalil Herbert Rushing Attempt D.J. Jones | 30-22 | |
| CHI | 4th | 6:34 | 1st | 10 | CHI 25 | Khalil Herbert Rushing Attempt D.J. Jones | 30-22 | |
| CHI | 4th | 9:32 | | | SF 15 | Cairo Santos XP Missed | 23-22 | |
| CHI | 4th | 11:08 | 1st | 10 | SF 31 | Justin Fields Incomplete Pass to Marquise Goodwin | 23-16 | |
| CHI | 4th | 14:11 | | | SF 35 | Jakeem Grant 30 yard Kick Return Attempt Marcell Harris | 23-16 | |
| SF | 3rd | 2:10 | 4th | 16 | CHI 32 | Brandon Aiyuk 21 yard Punt Return Attempt Patrick Scales, Xavier Crawford | 15-16 | |
| CHI | 3rd | 2:14 | 3rd | 16 | CHI 32 | Justin Fields Incomplete Pass to Cole Kmet | 15-16 | |
| CHI | 3rd | 5:56 | | | SF 35 | Jakeem Grant 24 yard Kick Return Attempt Jimmie Ward | 15-16 | |
| SF | 3rd | 5:56 | | | CHI 15 | Joey Slye XP Missed | 15-16 | |
| SF | 3rd | 6:03 | 2nd | Goal | CHI 2 | Jimmy Garoppolo Incomplete Pass to Brandon Aiyuk Jaylon Johnson | 9-16 | |
| SF | 3rd | 7:31 | 2nd | 19 | SF 16 | Jimmy Garoppolo Incomplete Pass to Charlie Woerner Tashaun Gipson | 9-16 | |
| SF | 3rd | 8:33 | 1st | 10 | SF 25 | Elijah Mitchell Rushing Attempt Jaylon Johnson | 9-16 | |
| CHI | 3rd | 8:39 | 3rd | Goal | SF 7 | Justin Fields Incomplete Pass to Cole Kmet | 9-13 | |
| CHI | 3rd | 13:03 | 1st | 10 | SF 35 | Justin Fields Incomplete Pass to Allen Robinson | 9-13 | |
| CHI | 3rd | 14:16 | 1st | 10 | Midfield | Khalil Herbert Rushing Attempt Arik Armstead | 9-13 | |
| CHI | 3rd | 15:00 | | | SF 35 | Jakeem Grant 34 yard Kick Return Attempt Dre Kirkpatrick | 9-13 | |
| SF | 2nd | 0:07 | 2nd | Goal | CHI 4 | Jimmy Garoppolo Incomplete Pass to Deebo Samuel | 6-13 | |
| SF | 2nd | 0:07 | 1st | Goal | CHI 4 | Jimmy Garoppolo Incomplete Pass | 6-13 | |
| SF | 2nd | 1:16 | 1st | 10 | SF 25 | Jimmy Garoppolo Incomplete Pass to Brandon Aiyuk | 6-13 | |
| CHI | 2nd | 8:49 | 2nd | 8 | CHI 23 | Justin Fields Incomplete Pass to Darnell Mooney Fred Warner | 6-10 | |
| CHI | 2nd | 9:33 | | | SF 35 | Jakeem Grant 10 yard Kick Return Attempt Dontae Johnson | 6-10 | |
| SF | 2nd | 9:42 | 3rd | 7 | CHI 34 | Jimmy Garoppolo Incomplete Pass to Mohamed Sanu DeAndre Houston-Carson | 3-10 | |
| SF | 2nd | 9:46 | 2nd | 7 | CHI 34 | Jimmy Garoppolo Incomplete Pass to Jauan Jennings Angelo Blackson | 3-10 | |
| CHI | 1st | 2:46 | 1st | 10 | CHI 26 | Justin Fields Incomplete Pass to Cole Kmet | 3-3 | |
| CHI | 1st | 2:51 | | | SF 35 | Jakeem Grant 31 yard Kick Return Attempt Trenton Cannon | 3-3 | |
| SF | 1st | 3:17 | 2nd | 9 | CHI 36 | Jimmy Garoppolo Incomplete Pass to Kyle Juszczyk | 0-3 | |
| SF | 1st | 9:52 | 4th | 5 | CHI 30 | Joey Slye 48 yard Field Goal Missed | 0-0 | |
| SF | 1st | 11:19 | 2nd | 14 | CHI 39 | Jimmy Garoppolo Incomplete Pass to Deebo Samuel | 0-0 | |
| SF | 1st | 14:50 | 2nd | 10 | SF 33 | Jimmy Garoppolo Incomplete Pass to Brandon Aiyuk | 0-0 | |
| SF | 1st | 14:54 | 1st | 10 | SF 33 | Jimmy Garoppolo Incomplete Pass to Deebo Samuel | 0-0 | |
| SF | 1st | 15:00 | | | CHI 35 | Trenton Cannon 29 yard Kick Return Attempt Christian Jones | 0-0 | |
| SF | 3rd | 7:28 | 3rd | 19 | SF 16 | Deebo Samuel 83 yard Passing Completion from Jimmy Garoppolo DeAndre Houston-Carson | 9-16 | 8.3 |
| CHI | 4th | 9:43 | 4th | 1 | SF 22 | Justin Fields 22 yard Rushing TD | 23-22 | 8.2 |
| CHI | 2nd | 12:09 | 2nd | 7 | SF 8 | Jesse James 8 yard Passing TD from Justin Fields | 3-9 | 6.8 |
| SF | 4th | 6:38 | 1st | Goal | CHI 5 | Jimmy Garoppolo 5 yard Rushing TD | 29-22 | 6.5 |
| SF | 4th | 14:21 | 1st | Goal | CHI 5 | Elijah Mitchell 5 yard Rushing TD | 21-16 | 6.5 |
| SF | 3rd | 6:00 | 3rd | Goal | CHI 2 | Jimmy Garoppolo 2 yard Rushing TD | 15-16 | 6.2 |
| SF | 2nd | 9:37 | 4th | 7 | CHI 34 | Joey Slye 52 yard Field Goal Made | 6-10 | 6 |
| SF | 2nd | 0:25 | 1st | 10 | SF 46 | Deebo Samuel 50 yard Passing Completion from Jimmy Garoppolo Kindle Vildor | 6-13 | 5 |
| CHI | 2nd | 1:20 | 4th | 12 | SF 22 | Cairo Santos 40 yard Field Goal Made | 6-13 | 4 |
| SF | 1st | 2:56 | 4th | 3 | CHI 30 | Joey Slye 48 yard Field Goal Made | 3-3 | 4 |
| SF | 4th | 4:24 | 1st | 10 | SF 37 | Elijah Mitchell 39 yard Rushing Attempt Akiem Hicks | 30-22 | 3.9 |
| SF | 4th | 2:00 | 4th | 11 | CHI 14 | Joey Slye 32 yard Field Goal Made | 33-22 | 3 |
| CHI | 3rd | 8:36 | 4th | Goal | SF 7 | Cairo Santos 25 yard Field Goal Made | 9-16 | 3 |
| SF | 2nd | 0:02 | 3rd | Goal | CHI 4 | Joey Slye 22 yard Field Goal Made | 9-13 | 3 |
| CHI | 1st | 4:42 | 4th | 8 | SF 21 | Cairo Santos 39 yard Field Goal Made | 0-3 | 3 |
| SF | 4th | 8:50 | 1st | 10 | SF 44 | Elijah Mitchell 27 yard Rushing Attempt Akiem Hicks | 23-22 | 2.7 |
| SF | 1st | 4:38 | 1st | 10 | SF 25 | Elijah Mitchell 27 yard Rushing Attempt Danny Trevathan | 0-3 | 2.7 |
| SF | 4th | 7:22 | 2nd | 9 | CHI 28 | JaMycal Hasty 23 yard Passing Completion from Jimmy Garoppolo DeAndre Houston-Carson, Trevis Gipson | 23-22 | 2.3 |
| SF | 2nd | 11:19 | 2nd | 11 | SF 24 | Brandon Aiyuk 23 yard Passing Completion from Jimmy Garoppolo Alec Ogletree | 3-10 | 2.3 |
| CHI | 3rd | 12:17 | 3rd | 13 | SF 38 | Marquise Goodwin 22 yard Passing Completion from Justin Fields Emmanuel Moseley | 9-13 | 2.2 |
| CHI | 1st | 7:58 | 1st | 10 | SF 45 | Khalil Herbert 22 yard Rushing Attempt Talanoa Hufanga | 0-0 | 2.2 |
| SF | 1st | 14:45 | 3rd | 10 | SF 33 | Mohamed Sanu 21 yard Passing Completion from Jimmy Garoppolo Kindle Vildor | 0-0 | 2.1 |
| SF | 4th | 1:50 | 1st | 10 | CHI 31 | Justin Fields Pass to Darnell Mooney Interception by Josh Norman Darnell Mooney | 33-22 | 2 |
| SF | 4th | 5:06 | 3rd | 10 | CHI 40 | -14 yard Sack Samson Ebukam | 30-22 | 2 |
| CHI | 4th | 11:40 | 1st | 15 | CHI 49 | Darnell Mooney 20 yard Passing Completion from Justin Fields Emmanuel Moseley | 23-16 | 2 |
| SF | 4th | 14:05 | 1st | 10 | CHI 32 | -1 yard Sack Marcell Harris | 23-16 | 2 |
| SF | 4th | 14:11 | | | CHI 2 | Brandon Aiyuk 2 Pt Conversion Passing from Jimmy Garoppolo | 23-16 | 2 |
| SF | 3rd | 2:54 | 2nd | 15 | CHI 33 | -1 yard Sack Nick Bosa | 15-16 | 2 |
| SF | 2nd | 3:35 | 1st | 10 | SF 30 | -11 yard Sack Nick Bosa | 6-10 | 2 |
| SF | 4th | 9:32 | 1st | 10 | SF 25 | Mohamed Sanu 19 yard Passing Completion from Jimmy Garoppolo Tashaun Gipson | 23-22 | 1.9 |
| CHI | 3rd | 14:52 | 1st | 10 | CHI 31 | Jesse James 19 yard Passing Completion from Justin Fields Josh Norman | 9-13 | 1.9 |
| SF | 1st | 10:35 | 3rd | 24 | CHI 49 | Mohamed Sanu 19 yard Passing Completion from Jimmy Garoppolo Alec Ogletree | 0-0 | 1.9 |
| CHI | 2nd | 3:11 | 2nd | 21 | SF 41 | Justin Fields 16 yard Rushing Attempt Fred Warner | 6-10 | 1.6 |
| CHI | 2nd | 6:32 | 1st | 10 | CHI 44 | Justin Fields 16 yard Rushing Attempt Talanoa Hufanga | 6-10 | 1.6 |
| SF | 2nd | 10:43 | 1st | 10 | SF 47 | Deebo Samuel 16 yard Passing Completion from Jimmy Garoppolo Jaylon Johnson | 3-10 | 1.6 |
| CHI | 1st | 1:09 | 1st | 10 | CHI 43 | Cole Kmet 16 yard Passing Completion from Justin Fields Jimmie Ward | 3-3 | 1.6 |
| SF | 3rd | 2:00 | 1st | 10 | SF 48 | Deebo Samuel 15 yard Passing Completion from Jimmy Garoppolo Roquan Smith | 15-16 | 1.5 |
| CHI | 3rd | 13:39 | 2nd | 10 | Midfield | Justin Fields 15 yard Rushing Attempt Fred Warner | 9-13 | 1.5 |
| SF | 2nd | 0:30 | 3rd | 4 | SF 31 | Brandon Aiyuk 15 yard Passing Completion from Jimmy Garoppolo Tashaun Gipson | 6-13 | 1.5 |
| CHI | 4th | 12:51 | 3rd | 1 | CHI 41 | Justin Fields 14 yard Rushing Attempt Talanoa Hufanga | 23-16 | 1.4 |
| CHI | 1st | 8:37 | 3rd | 7 | CHI 41 | Darnell Mooney 14 yard Passing Completion from Justin Fields Emmanuel Moseley | 0-0 | 1.4 |
| SF | 4th | 3:27 | 2nd | 11 | CHI 25 | Elijah Mitchell 12 yard Rushing Attempt DeAndre Houston-Carson | 30-22 | 1.2 |
| SF | 4th | 15:00 | 1st | 10 | CHI 16 | Elijah Mitchell 11 yard Rushing Attempt DeAndre Houston-Carson | 15-16 | 1.1 |
| SF | 3rd | 0:28 | 1st | 10 | CHI 27 | Kyle Juszczyk 11 yard Passing Completion from Jimmy Garoppolo DeAndre Houston-Carson | 15-16 | 1.1 |
| CHI | 1st | 1:45 | 3rd | 4 | CHI 32 | Darnell Mooney 11 yard Passing Completion from Justin Fields Fred Warner | 3-3 | 1.1 |
| SF | 1st | 4:10 | 1st | 10 | CHI 48 | Deebo Samuel 11 yard Passing Completion from Jimmy Garoppolo Danny Trevathan | 0-3 | 1.1 |
| CHI | 1st | 5:24 | 3rd | 19 | SF 32 | Jesse James 11 yard Passing Completion from Justin Fields Tavon Wilson | 0-0 | 1.1 |
| SF | 4th | 6:34 | | | CHI 15 | Joey Slye XP | 30-22 | 1 |
| CHI | 4th | 13:32 | 2nd | 11 | CHI 31 | Marquise Goodwin 10 yard Passing Completion from Justin Fields Josh Norman | 23-16 | 1 |
| CHI | 2nd | 8:44 | 3rd | 8 | CHI 23 | Allen Robinson 10 yard Passing Completion from Justin Fields K'Waun Williams | 6-10 | 1 |
| CHI | 2nd | 12:03 | | | SF 15 | Cairo Santos XP | 3-10 | 1 |
| CHI | 3rd | 4:36 | 1st | 10 | CHI 26 | Darnell Mooney 9 yard Passing Completion from Justin Fields Fred Warner | 15-16 | 0.9 |
| CHI | 2nd | 4:52 | 2nd | 12 | SF 42 | Khalil Herbert 9 yard Rushing Attempt Jimmie Ward | 6-10 | 0.9 |
| CHI | 2nd | 14:37 | 3rd | 1 | SF 32 | Justin Fields 9 yard Rushing Attempt K'Waun Williams | 3-3 | 0.9 |
| SF | 3rd | 0:54 | 2nd | 7 | CHI 34 | Charlie Woerner 7 yard Passing Completion from Jimmy Garoppolo Danny Trevathan, Sam Kamara | 15-16 | 0.7 |
| SF | 1st | 14:08 | 1st | 10 | CHI 46 | Elijah Mitchell 7 yard Rushing Attempt Robert Quinn, Trevis Gipson | 0-0 | 0.7 |
| CHI | 3rd | 5:12 | 2nd | 6 | CHI 20 | Khalil Herbert 6 yard Rushing Attempt Arik Armstead | 15-16 | 0.6 |
| CHI | 3rd | 11:11 | 2nd | 14 | SF 20 | Allen Robinson 6 yard Passing Completion from Justin Fields Jimmie Ward | 9-13 | 0.6 |
| SF | 2nd | 1:10 | 2nd | 10 | SF 25 | Brandon Aiyuk 6 yard Passing Completion from Jimmy Garoppolo Jaylon Johnson | 6-13 | 0.6 |
| CHI | 2nd | 13:25 | 2nd | 4 | SF 17 | Cole Kmet 6 yard Passing Completion from Justin Fields Marcell Harris | 3-3 | 0.6 |
| CHI | 2nd | 14:03 | 1st | 10 | SF 23 | Khalil Herbert 6 yard Rushing Attempt Fred Warner | 3-3 | 0.6 |
| CHI | 2nd | 15:00 | 2nd | 7 | SF 38 | Khalil Herbert 6 yard Rushing Attempt Kentavius Street | 3-3 | 0.6 |
| SF | 1st | 3:12 | 3rd | 9 | CHI 36 | JaMycal Hasty 6 yard Passing Completion from Jimmy Garoppolo Roquan Smith | 0-3 | 0.6 |
| CHI | 1st | 7:05 | 1st | 18 | SF 31 | Darnell Mooney 6 yard Passing Completion from Justin Fields Josh Norman | 0-0 | 0.6 |
| CHI | 4th | 10:20 | 3rd | 6 | SF 27 | Allen Robinson 5 yard Passing Completion from Justin Fields Josh Norman | 23-16 | 0.5 |
| CHI | 4th | 11:03 | 2nd | 10 | SF 31 | Khalil Herbert 4 yard Rushing Attempt Arik Armstead | 23-16 | 0.4 |
| CHI | 4th | 12:21 | 1st | 10 | SF 45 | Ryan Nall 4 yard Rushing Attempt Josh Norman, K'Waun Williams | 23-16 | 0.4 |
| CHI | 3rd | 5:52 | 1st | 10 | CHI 16 | Khalil Herbert 4 yard Rushing Attempt Fred Warner | 15-16 | 0.4 |
| SF | 3rd | 6:45 | 1st | Goal | CHI 6 | Elijah Mitchell 4 yard Rushing Attempt Jaylon Johnson | 9-16 | 0.4 |
| CHI | 2nd | 6:51 | 3rd | 3 | CHI 40 | Darnell Mooney 4 yard Passing Completion from Justin Fields | 6-10 | 0.4 |
| CHI | 2nd | 7:29 | 2nd | 7 | CHI 36 | Khalil Herbert 4 yard Rushing Attempt Fred Warner | 6-10 | 0.4 |
| CHI | 1st | 9:12 | 2nd | 11 | CHI 37 | Justin Fields 4 yard Rushing Attempt Josh Norman | 0-0 | 0.4 |
| SF | 3rd | 1:26 | 1st | 10 | CHI 37 | Elijah Mitchell 3 yard Rushing Attempt Akiem Hicks | 15-16 | 0.3 |
| CHI | 3rd | 3:59 | 2nd | 1 | CHI 35 | Khalil Herbert 3 yard Rushing Attempt Fred Warner, Arik Armstead | 15-16 | 0.3 |
| CHI | 2nd | 4:17 | 3rd | 3 | SF 33 | Khalil Herbert 3 yard Rushing Attempt Samson Ebukam | 6-10 | 0.3 |
| CHI | 2nd | 5:32 | 1st | 15 | SF 45 | Khalil Herbert 3 yard Rushing Attempt Jimmie Ward | 6-10 | 0.3 |
| CHI | 2nd | 8:08 | 1st | 10 | CHI 33 | Justin Fields 3 yard Rushing Attempt Marcell Harris | 6-10 | 0.3 |
| SF | 2nd | 10:08 | 1st | 10 | CHI 37 | Elijah Mitchell 3 yard Rushing Attempt Robert Quinn | 3-10 | 0.3 |
| CHI | 2nd | 12:45 | 1st | 10 | SF 11 | Khalil Herbert 3 yard Rushing Attempt Jimmie Ward | 3-3 | 0.3 |
| CHI | 1st | 0:30 | 1st | 10 | SF 41 | Khalil Herbert 3 yard Rushing Attempt Kevin Givens | 3-3 | 0.3 |
| CHI | 3rd | 9:19 | 2nd | Goal | SF 9 | Khalil Herbert 2 yard Passing Completion from Justin Fields Demetrius Flannigan-Fowles | 9-13 | 0.2 |
| CHI | 2nd | 2:00 | 2nd | 8 | SF 18 | Cole Kmet 2 yard Passing Completion from Justin Fields Marcell Harris | 6-10 | 0.2 |
| CHI | 2nd | 2:39 | 1st | 10 | SF 20 | Khalil Herbert 2 yard Rushing Attempt Marcell Harris | 6-10 | 0.2 |
| CHI | 2nd | 9:27 | 1st | 10 | CHI 21 | Khalil Herbert 2 yard Rushing Attempt D.J. Jones | 6-10 | 0.2 |
| CHI | 1st | 7:33 | 1st | 10 | SF 23 | Khalil Herbert 2 yard Rushing Attempt Emmanuel Moseley | 0-0 | 0.2 |
| SF | 1st | 12:36 | 4th | 1 | CHI 37 | JaMycal Hasty 2 yard Rushing Attempt Trevis Gipson | 0-0 | 0.2 |
| SF | 4th | 2:29 | 3rd | 12 | CHI 15 | JaMycal Hasty 1 yard Rushing Attempt Tashaun Gipson | 30-22 | 0.1 |
| SF | 4th | 8:01 | 1st | 10 | CHI 29 | Elijah Mitchell 1 yard Rushing Attempt Roquan Smith | 23-22 | 0.1 |
| SF | 3rd | 8:00 | 2nd | 10 | SF 25 | Brandon Aiyuk 1 yard Passing Completion from Jimmy Garoppolo Alec Ogletree | 9-16 | 0.1 |
| CHI | 1st | 2:41 | 2nd | 10 | CHI 26 | Khalil Herbert 1 yard Rushing Attempt Kentavius Street | 3-3 | 0.1 |
| SF | 1st | 3:43 | 1st | 10 | CHI 37 | Elijah Mitchell 1 yard Rushing Attempt Roquan Smith | 0-3 | 0.1 |
| SF | 1st | 13:00 | 3rd | 2 | CHI 38 | JaMycal Hasty 1 yard Rushing Attempt Eddie Goldman | 0-0 | 0.1 |
| SF | 1st | 13:39 | 2nd | 3 | CHI 39 | Elijah Mitchell 1 yard Rushing Attempt Trevis Gipson, Alec Ogletree | 0-0 | 0.1 |
| SF | 4th | 0:31 | 3rd | 12 | SF 48 | Jimmy Garoppolo -1 yard Rushing Attempt | 33-22 | -0.1 |
| SF | 4th | 0:52 | 2nd | 11 | SF 49 | Jimmy Garoppolo -1 yard Rushing Attempt | 33-22 | -0.1 |
| SF | 4th | 1:34 | 1st | 10 | Midfield | Jimmy Garoppolo -1 yard Rushing Attempt | 33-22 | -0.1 |
| SF | 4th | 3:30 | 1st | 10 | CHI 24 | Elijah Mitchell -1 yard Rushing Attempt Roquan Smith | 30-22 | -0.1 |
| SF | 2nd | 12:03 | 1st | 10 | SF 25 | Elijah Mitchell -1 yard Rushing Attempt Khyiris Tonga | 3-10 | -0.1 |
| CHI | 1st | 9:48 | 1st | 10 | CHI 38 | Damien Williams -1 yard Rushing Attempt D.J. Jones, K'Waun Williams | 0-0 | -0.1 |
| SF | 4th | 3:18 | 1st | 10 | CHI 13 | Elijah Mitchell -2 yard Rushing Attempt Akiem Hicks, Roquan Smith | 30-22 | -0.2 |
| CHI | 1st | 6:37 | 2nd | 12 | SF 25 | Damien Williams -2 yard Rushing Attempt Talanoa Hufanga | 0-0 | -0.2 |
| SF | 1st | 11:59 | 1st | 10 | CHI 35 | Deebo Samuel -4 yard Passing Completion from Jimmy Garoppolo Robert Quinn | 0-0 | -0.2 |
| CHI | 3rd | 13:00 | 2nd | 10 | SF 35 | Khalil Herbert -3 yard Rushing Attempt Nick Bosa | 9-13 | -0.3 |
| CHI | 2nd | 1:25 | 3rd | 6 | SF 16 | Khalil Herbert -6 yard Passing Completion from Justin Fields K'Waun Williams | 6-10 | -0.3 |
| CHI | 3rd | 9:59 | 1st | Goal | SF 5 | Khalil Herbert -4 yard Rushing Attempt D.J. Jones | 9-13 | -0.4 |
| CHI | 3rd | 11:52 | 1st | 10 | SF 16 | Khalil Herbert -4 yard Rushing Attempt K'Waun Williams | 9-13 | -0.4 |
| CHI | 3rd | 10:26 | 3rd | 8 | SF 14 | Justin Fields Rushing Attempt Fumble Josh Norman | 9-13 | -0.6 |
| CHI | 3rd | 3:20 | 1st | 10 | CHI 38 | Justin Fields Rushing Attempt Fumble recovered by Khalil Herbert | 15-16 | -1 |