| Team | | Time | Down | Distance | Pos | Description | Score | Max Pts |
|---|
| SF | 3rd | 12:04 | 3rd | 20 | DET 36 | Trey Lance 2 yard Rushing Attempt Will Harris | 31-10 | 0.2 |
| DET | 2nd | 1:03 | 3rd | 20 | DET 15 | Jamaal Williams 7 yard Passing Completion from Jared Goff K'Waun Williams | 27-10 | 0.7 |
| DET | 1st | 3:22 | 2nd | 20 | Midfield | D'Andre Swift 12 yard Passing Completion from Jared Goff Fred Warner | 7-0 | 1.2 |
| SF | 4th | 10:45 | 3rd | 18 | DET 46 | George Kittle 12 yard Passing Completion from Jimmy Garoppolo Kevin Strong | 38-17 | 1.2 |
| SF | 3rd | 11:26 | 4th | 18 | DET 34 | Robbie Gould 52 yard Field Goal Missed | 31-10 | |
| DET | 1st | 9:41 | 4th | 18 | SF 33 | Austin Seibert 51 yard Field Goal Missed | 0-0 | |
| DET | 1st | 9:46 | 3rd | 18 | SF 33 | Jared Goff Incomplete Pass to D'Andre Swift | 0-0 | |
| SF | 4th | 1:06 | 1st | 15 | DET 48 | Elijah Mitchell 1 yard Rushing Attempt Alim McNeill | 41-33 | 0.1 |
| SF | 4th | 13:40 | 4th | 15 | DET 7 | Mohamed Sanu 11 yard Punt Return Attempt Jerry Jacobs | 38-17 | |
| DET | 2nd | 7:01 | 3rd | 15 | SF 38 | Tyrell Williams 7 yard Passing Completion from Jared Goff Fred Warner | 14-7 | 0.7 |
| SF | 4th | 1:02 | 2nd | 14 | DET 47 | Elijah Mitchell 1 yard Rushing Attempt Derrick Barnes | 41-33 | 0.1 |
| SF | 2nd | 1:07 | 2nd | 14 | DET 21 | -6 yard Sack Dee Ford | 27-10 | 2 |
| SF | 4th | 0:58 | 3rd | 13 | DET 46 | Deebo Samuel Passing Completion from Jimmy Garoppolo Fumble Lost recovered by Ifeatu Melifonwu Trey Flowers | 41-33 | 1 |
| SF | 2nd | 0:56 | 4th | 13 | DET 22 | Brandon Aiyuk 7 yard Punt Return Attempt Jason Cabinda | 27-10 | |
| DET | 2nd | 7:23 | 2nd | 11 | SF 34 | D'Andre Swift -4 yard Rushing Attempt Nick Bosa | 14-7 | -0.4 |
| SF | 4th | 0:12 | 1st | 10 | SF 24 | Jimmy Garoppolo -1 yard Rushing Attempt | 41-33 | -0.1 |
| DET | 4th | 0:27 | 2nd | 10 | SF 25 | Jared Goff 1 yard Rushing Attempt Arik Armstead | 41-33 | 0.1 |
| DET | 4th | 0:32 | 1st | 10 | SF 25 | Jared Goff Incomplete Pass | 41-33 | |
| DET | 4th | 0:37 | 2nd | 10 | Midfield | Kalif Raymond 25 yard Passing Completion from Jared Goff Jimmie Ward | 41-33 | 2.5 |
| DET | 4th | 0:42 | 1st | 10 | Midfield | Jared Goff Incomplete Pass to Quintez Cephus | 41-33 | |
| DET | 4th | 0:47 | 2nd | 10 | DET 30 | Amon-Ra St. Brown 20 yard Passing Completion from Jared Goff Dontae Johnson | 41-33 | 2 |
| DET | 4th | 0:52 | 1st | 10 | DET 30 | Jared Goff Incomplete Pass to Trinity Benson Dontae Johnson | 41-33 | |
| DET | 4th | 1:22 | 1st | 10 | SF 25 | Quintez Cephus 3 yard Passing Completion from Jared Goff Dontae Johnson | 41-25 | 0.3 |
| DET | 4th | 1:29 | 1st | 10 | SF 35 | Jared Goff 10 yard Rushing Attempt Azeez Al-Shaair | 41-25 | 1 |
| DET | 4th | 1:37 | 1st | 10 | SF 48 | T.J. Hockenson 13 yard Passing Completion from Jared Goff Ambry Thomas | 41-25 | 1.3 |
| DET | 4th | 1:53 | 1st | 10 | DET 41 | Trinity Benson 11 yard Passing Completion from Jared Goff Ambry Thomas | 41-25 | 1.1 |
| DET | 4th | 2:33 | 1st | 10 | SF 33 | Quintez Cephus 7 yard Passing Completion from Jared Goff Demetrius Flannigan-Fowles | 41-17 | 0.7 |
| DET | 4th | 3:25 | 1st | 10 | SF 44 | Jamaal Williams 3 yard Passing Completion from Jared Goff Samson Ebukam | 41-17 | 0.3 |
| DET | 4th | 4:09 | 2nd | 10 | DET 45 | D'Andre Swift 6 yard Passing Completion from Jared Goff Deommodore Lenoir | 41-17 | 0.6 |
| DET | 4th | 4:15 | 1st | 10 | DET 45 | Jared Goff Incomplete Pass to D'Andre Swift Azeez Al-Shaair | 41-17 | |
| DET | 4th | 4:57 | 1st | 10 | DET 27 | D'Andre Swift 5 yard Passing Completion from Jared Goff Fred Warner | 41-17 | 0.5 |
| DET | 4th | 5:45 | 1st | 10 | DET 14 | Trinity Benson 3 yard Passing Completion from Jared Goff Deommodore Lenoir | 41-17 | 0.3 |
| SF | 4th | 7:28 | 1st | 10 | SF 47 | Elijah Mitchell 6 yard Rushing Attempt AJ Parker | 41-17 | 0.6 |
| DET | 4th | 7:50 | 3rd | 10 | DET 48 | Kalif Raymond 5 yard Passing Completion from Jared Goff | 41-17 | 0.5 |
| DET | 4th | 7:54 | 2nd | 10 | DET 48 | Jared Goff Incomplete Pass to Trinity Benson | 41-17 | |
| DET | 4th | 9:33 | 1st | 10 | DET 48 | Trinity Benson 5 yard Passing Completion from Jared Goff Jason Verrett | 41-17 | 0.5 |
| DET | 4th | 9:53 | 1st | 10 | DET 25 | T.J. Hockenson 23 yard Passing Completion from Jared Goff Jimmie Ward | 41-17 | 2.3 |
| DET | 4th | 11:28 | 2nd | 10 | DET 38 | -8 yard Sack Tracy Walker | 38-17 | 2 |
| SF | 4th | 12:03 | 1st | 10 | DET 38 | Elijah Mitchell Rushing Attempt Jamie Collins | 38-17 | |
| SF | 4th | 12:47 | 3rd | 10 | SF 47 | JaMycal Hasty 15 yard Passing Completion from Jimmy Garoppolo Jeff Okudah | 38-17 | 1.5 |
| SF | 4th | 12:55 | 2nd | 10 | SF 47 | Jimmy Garoppolo Incomplete Pass to Trent Sherfield Jeff Okudah | 38-17 | |
| SF | 4th | 13:38 | 1st | 10 | SF 47 | Elijah Mitchell Rushing Attempt Jamie Collins | 38-17 | |
| DET | 3rd | 0:34 | 1st | 10 | DET 12 | Amon-Ra St. Brown 3 yard Passing Completion from Jared Goff Fred Warner | 38-17 | 0.3 |
| SF | 3rd | 2:58 | 1st | 10 | SF 37 | Deebo Samuel 2 yard Passing Completion from Jimmy Garoppolo Kevin Strong | 38-17 | 0.2 |
| SF | 3rd | 4:18 | 1st | 10 | SF 20 | Elijah Mitchell 1 yard Rushing Attempt AJ Parker | 38-17 | 0.1 |
| DET | 3rd | 5:22 | 1st | 10 | SF 49 | Jamaal Williams 6 yard Passing Completion from Jared Goff Azeez Al-Shaair | 38-10 | 0.6 |
| DET | 3rd | 6:04 | 1st | 10 | DET 40 | Jamaal Williams 11 yard Passing Completion from Jared Goff Fred Warner, Azeez Al-Shaair | 38-10 | 1.1 |
| DET | 3rd | 7:54 | 1st | 10 | DET 25 | Jared Goff 3 yard Rushing Attempt K'Waun Williams | 38-10 | 0.3 |
| SF | 3rd | 8:48 | 2nd | 10 | SF 19 | Elijah Mitchell 2 yard Rushing Attempt Jamie Collins | 31-10 | 0.2 |
| SF | 3rd | 8:54 | 1st | 10 | SF 19 | Jimmy Garoppolo Incomplete Pass to Deebo Samuel | 31-10 | |
| SF | 3rd | 10:16 | 1st | 10 | SF 9 | Elijah Mitchell 7 yard Rushing Attempt Michael Brockers | 31-10 | 0.7 |
| DET | 3rd | 11:10 | 1st | 10 | SF 43 | D'Andre Swift 1 yard Rushing Attempt Fred Warner | 31-10 | 0.1 |
| DET | 3rd | 11:20 | 1st | 10 | DET 42 | Jared Goff Incomplete Pass to Kalif Raymond | 31-10 | |
| SF | 3rd | 12:09 | 2nd | 10 | DET 26 | Jimmy Garoppolo Incomplete Pass | 31-10 | |
| SF | 3rd | 12:15 | 1st | 10 | DET 26 | Jimmy Garoppolo Incomplete Pass to Deebo Samuel | 31-10 | |
| SF | 3rd | 12:55 | 1st | 10 | DET 36 | Elijah Mitchell 10 yard Rushing Attempt Tracy Walker | 31-10 | 1 |
| SF | 3rd | 14:07 | 1st | 10 | DET 46 | Elijah Mitchell 2 yard Rushing Attempt Michael Brockers | 31-10 | 0.2 |
| SF | 3rd | 14:55 | 1st | 10 | SF 19 | George Kittle 35 yard Passing Completion from Jimmy Garoppolo Trey Flowers | 31-10 | 3.5 |
| SF | 2nd | 0:28 | 1st | 10 | DET 25 | Jimmy Garoppolo 3 yard Rushing Attempt Alex Anzalone | 27-10 | 0.3 |
| SF | 2nd | 0:35 | 2nd | 10 | DET 43 | Trent Sherfield 18 yard Passing Completion from Jimmy Garoppolo Alex Anzalone | 27-10 | 1.8 |
| SF | 2nd | 0:39 | 1st | 10 | DET 43 | Jimmy Garoppolo Incomplete Pass to George Kittle Amani Oruwariye | 27-10 | |
| SF | 2nd | 0:44 | 1st | 10 | SF 28 | Deebo Samuel 14 yard Passing Completion from Jimmy Garoppolo Tracy Walker | 27-10 | 1.4 |
| DET | 2nd | 1:10 | 1st | 10 | DET 25 | D'Andre Swift -4 yard Rushing Attempt Nick Bosa | 27-10 | -0.4 |
| DET | 2nd | 2:00 | 1st | 10 | DET 30 | D'Andre Swift 3 yard Rushing Attempt Fred Warner | 21-10 | 0.3 |
| DET | 2nd | 2:19 | 1st | 10 | DET 20 | T.J. Hockenson 10 yard Passing Completion from Jared Goff Jaquiski Tartt | 21-10 | 1 |
| SF | 2nd | 3:52 | 1st | 10 | DET 13 | Elijah Mitchell 3 yard Rushing Attempt Alim McNeill, Alex Anzalone | 14-10 | 0.3 |
| SF | 2nd | 4:39 | 1st | 10 | DET 36 | Deebo Samuel 23 yard Passing Completion from Jimmy Garoppolo Alex Anzalone | 14-10 | 2.3 |
| SF | 2nd | 6:00 | 1st | 10 | SF 47 | Elijah Mitchell 6 yard Rushing Attempt Alim McNeill, Michael Brockers | 14-10 | 0.6 |
| SF | 2nd | 6:07 | 1st | 10 | SF 25 | Kyle Juszczyk 7 yard Passing Completion from Jimmy Garoppolo Amani Oruwariye | 14-10 | 0.7 |
| DET | 2nd | 8:00 | 1st | 10 | SF 33 | D'Andre Swift -1 yard Rushing Attempt Jaquiski Tartt, Kevin Givens | 14-7 | -0.1 |
| DET | 2nd | 8:36 | 1st | 10 | SF 48 | D'Andre Swift 15 yard Rushing Attempt Jimmie Ward | 14-7 | 1.5 |
| DET | 2nd | 9:11 | 1st | 10 | DET 36 | D'Andre Swift 16 yard Rushing Attempt Jimmie Ward | 14-7 | 1.6 |
| DET | 2nd | 11:12 | 1st | 10 | DET 25 | Jamaal Williams 3 yard Rushing Attempt Dre Greenlaw | 14-7 | 0.3 |
| SF | 2nd | 12:07 | 1st | 10 | DET 46 | Deebo Samuel 8 yard Passing Completion from Jimmy Garoppolo Will Harris | 7-7 | 0.8 |
| SF | 2nd | 13:23 | 1st | 10 | SF 22 | Elijah Mitchell 3 yard Rushing Attempt Kevin Strong | 7-7 | 0.3 |
| DET | 2nd | 15:00 | 1st | Goal | SF 10 | D'Andre Swift 1 yard Rushing Attempt Jason Verrett | 7-0 | 0.1 |
| DET | 1st | 1:55 | 1st | 10 | SF 26 | D'Andre Swift 7 yard Rushing Attempt Jason Verrett | 7-0 | 0.7 |
| SF | 1st | 4:04 | 1st | 10 | SF 40 | -10 yard Sack Kentavius Street | 7-0 | 2 |
| DET | 1st | 4:48 | 1st | 10 | DET 38 | Jamaal Williams 7 yard Rushing Attempt K'Waun Williams | 7-0 | 0.7 |
| DET | 1st | 5:31 | 2nd | 10 | DET 18 | Jamaal Williams 20 yard Rushing Attempt Jimmie Ward | 7-0 | 2 |
| DET | 1st | 5:34 | 1st | 10 | DET 18 | Jared Goff Incomplete Pass to T.J. Hockenson | 7-0 | |
| SF | 1st | 7:40 | 1st | 10 | DET 16 | Trey Lance 1 yard Rushing Attempt Michael Brockers | 0-0 | 0.1 |
| SF | 1st | 9:00 | 1st | 10 | DET 48 | Raheem Mostert 9 yard Rushing Attempt Tracy Walker | 0-0 | 0.9 |
| SF | 1st | 9:36 | 1st | 10 | SF 41 | Raheem Mostert 11 yard Rushing Attempt Will Harris | 0-0 | 1.1 |
| DET | 1st | 10:29 | 2nd | 10 | SF 25 | D'Andre Swift -8 yard Passing Completion from Jared Goff Azeez Al-Shaair | 0-0 | -0.4 |
| DET | 1st | 10:35 | 1st | 10 | SF 25 | Jared Goff Incomplete Pass to Amon-Ra St. Brown | 0-0 | |
| DET | 1st | 11:56 | 1st | 10 | SF 38 | D'Andre Swift 4 yard Rushing Attempt Dre Greenlaw | 0-0 | 0.4 |
| SF | 1st | 12:01 | 1st | 10 | SF 36 | Jimmy Garoppolo Rushing Attempt Fumble Lost recovered by Jamie Collins | 0-0 | 1 |
| DET | 1st | 13:37 | 1st | 10 | SF 43 | Jamaal Williams 2 yard Rushing Attempt Nick Bosa | 0-0 | 0.2 |
| DET | 1st | 14:18 | 1st | 10 | DET 35 | T.J. Hockenson 22 yard Passing Completion from Jared Goff Jimmie Ward | 0-0 | 2.2 |
| DET | 1st | 14:53 | 1st | 10 | DET 25 | Jamaal Williams 10 yard Rushing Attempt Jaquiski Tartt | 0-0 | 1 |
| DET | 4th | 0:17 | 4th | 9 | SF 24 | Jared Goff Incomplete Pass to Amon-Ra St. Brown | 41-33 | |
| DET | 4th | 0:20 | 3rd | 9 | SF 24 | Jared Goff Incomplete Pass to T.J. Hockenson Azeez Al-Shaair | 41-33 | |
| SF | 3rd | 3:40 | 2nd | 9 | SF 21 | Deebo Samuel 16 yard Passing Completion from Jimmy Garoppolo Will Harris | 38-17 | 1.6 |
| DET | 3rd | 10:27 | 3rd | 9 | SF 42 | Jared Goff Incomplete Pass to Jamaal Williams | 31-10 | |
| DET | 3rd | 10:33 | 2nd | 9 | SF 42 | Jared Goff Incomplete Pass to D'Andre Swift | 31-10 | |
| DET | 2nd | 14:20 | 2nd | Goal | SF 9 | D'Andre Swift 3 yard Passing Completion from Jared Goff Dre Greenlaw | 7-0 | 0.3 |
| SF | 1st | 7:11 | 2nd | 9 | DET 15 | Elijah Mitchell 3 yard Rushing Attempt Michael Brockers | 0-0 | 0.3 |
| SF | 3rd | 2:12 | 2nd | 8 | SF 39 | Elijah Mitchell 7 yard Rushing Attempt Jamie Collins | 38-17 | 0.7 |
| SF | 3rd | 8:08 | 3rd | 8 | SF 21 | Deebo Samuel 79 yard Passing TD from Jimmy Garoppolo | 37-10 | 15.9 |
| SF | 3rd | 13:37 | 2nd | 8 | DET 44 | George Kittle 8 yard Passing Completion from Jimmy Garoppolo Tracy Walker | 31-10 | 0.8 |
| SF | 2nd | 1:20 | 3rd | 8 | DET 32 | Dre Greenlaw 39 yard INT Return TD | 27-10 | 8 |
| DET | 2nd | 6:21 | 4th | 8 | SF 31 | Austin Seibert 49 yard Field Goal Made | 14-10 | 4 |
| DET | 1st | 2:38 | 3rd | 8 | SF 38 | T.J. Hockenson 12 yard Passing Completion from Jared Goff | 7-0 | 1.2 |
| DET | 4th | 1:18 | 2nd | 7 | SF 22 | Kalif Raymond 20 yard Passing Completion from Jared Goff | 41-25 | 2 |
| DET | 4th | 3:04 | 2nd | 7 | SF 41 | Jamaal Williams 8 yard Passing Completion from Jared Goff Demetrius Flannigan-Fowles | 41-17 | 0.8 |
| DET | 4th | 5:25 | 2nd | 7 | DET 17 | T.J. Hockenson 10 yard Passing Completion from Jared Goff | 41-17 | 1 |
| SF | 4th | 13:53 | 3rd | 7 | DET 15 | -8 yard Sack Nick Bosa | 38-17 | 2 |
| DET | 4th | 15:00 | 2nd | 7 | DET 15 | Jared Goff Incomplete Pass to Quintez Cephus | 38-17 | |
| DET | 3rd | 7:16 | 2nd | 7 | DET 28 | Jamaal Williams 6 yard Rushing Attempt Jaquiski Tartt | 38-10 | 0.6 |
| SF | 2nd | 0:08 | 4th | 7 | DET 22 | Robbie Gould 40 yard Field Goal Made | 30-10 | 4 |
| SF | 2nd | 0:12 | 3rd | 7 | DET 22 | Jimmy Garoppolo Incomplete Pass | 27-10 | |
| SF | 2nd | 0:13 | 2nd | 7 | DET 22 | Jimmy Garoppolo Incomplete Pass | 27-10 | |
| DET | 2nd | 1:28 | 2nd | 7 | DET 33 | D'Andre Swift -1 yard Passing Completion from Jared Goff Azeez Al-Shaair | 21-10 | -0.05 |
| SF | 2nd | 3:13 | 2nd | 7 | DET 10 | Deebo Samuel 7 yard Passing Completion from Jimmy Garoppolo | 14-10 | 0.7 |
| DET | 2nd | 10:39 | 2nd | 7 | DET 28 | Darren Fells 2 yard Passing Completion from Jared Goff Dre Greenlaw | 14-7 | 0.2 |
| SF | 2nd | 12:51 | 2nd | 7 | SF 25 | Deebo Samuel 29 yard Passing Completion from Jimmy Garoppolo Jeff Okudah | 7-7 | 2.9 |
| DET | 1st | 12:52 | 3rd | 7 | SF 41 | Jamaal Williams 6 yard Passing Completion from Jared Goff Fred Warner | 0-0 | 0.6 |
| DET | 1st | 12:56 | 2nd | 7 | SF 41 | Jared Goff Incomplete Pass to Tyrell Williams | 0-0 | |
| SF | 4th | 10:00 | 4th | 6 | DET 34 | Robbie Gould 52 yard Field Goal Made | 41-17 | 6 |
| DET | 2nd | 13:34 | 3rd | Goal | SF 6 | T.J. Hockenson 6 yard Passing TD from Jared Goff | 7-6 | 6.6 |
| SF | 1st | 6:29 | 3rd | 6 | DET 12 | Mohamed Sanu 7 yard Passing Completion from Jimmy Garoppolo Jeff Okudah | 0-0 | 0.7 |
| DET | 1st | 11:21 | 2nd | 6 | SF 34 | Kalif Raymond 9 yard Rushing Attempt Azeez Al-Shaair | 0-0 | 0.9 |
| DET | 4th | 4:25 | 2nd | 5 | DET 32 | Jared Goff Incomplete Pass to Quintez Cephus | 41-17 | |
| DET | 4th | 7:32 | 4th | 5 | SF 47 | Jared Goff Incomplete Pass to Trinity Benson | 41-17 | |
| DET | 2nd | 9:51 | 3rd | 5 | DET 30 | Jamaal Williams 6 yard Passing Completion from Jared Goff Dre Greenlaw | 14-7 | 0.6 |
| SF | 1st | 5:47 | 1st | Goal | DET 5 | Trent Sherfield 5 yard Passing TD from Trey Lance | 6-0 | 6.5 |
| DET | 4th | 3:47 | 3rd | 4 | SF 49 | D'Andre Swift 5 yard Passing Completion from Jared Goff Demetrius Flannigan-Fowles | 41-17 | 0.5 |
| SF | 4th | 6:02 | 3rd | 4 | DET 47 | Jimmy Garoppolo Incomplete Pass to Deebo Samuel | 41-17 | |
| SF | 4th | 6:44 | 2nd | 4 | DET 47 | Elijah Mitchell Rushing Attempt Trey Flowers | 41-17 | |
| DET | 3rd | 4:38 | 2nd | 4 | SF 43 | D'Andre Swift 43 yard Passing TD from Jared Goff | 38-16 | 12.3 |
| SF | 2nd | 5:19 | 2nd | 4 | DET 47 | Elijah Mitchell 11 yard Rushing Attempt Jeff Okudah | 14-10 | 1.1 |
| DET | 4th | 2:11 | 2nd | 3 | SF 26 | Jamaal Williams 9 yard Passing Completion from Jared Goff Marcell Harris | 41-17 | 0.9 |
| SF | 3rd | 9:35 | 2nd | 3 | SF 16 | Elijah Mitchell 3 yard Rushing Attempt Trey Flowers | 31-10 | 0.3 |
| SF | 2nd | 2:30 | 1st | Goal | DET 3 | JaMycal Hasty 3 yard Rushing TD | 20-10 | 6.3 |
| DET | 1st | 1:17 | 2nd | 3 | SF 19 | D'Andre Swift 1 yard Rushing Attempt Jaquiski Tartt | 7-0 | 0.1 |
| DET | 4th | 1:10 | 1st | Goal | SF 2 | Quintez Cephus 2 yard Passing TD from Jared Goff | 41-31 | 6.2 |
| SF | 2nd | 11:22 | 2nd | 2 | DET 38 | Elijah Mitchell 38 yard Rushing TD | 13-7 | 9.8 |
| DET | 1st | 0:52 | 3rd | 2 | SF 18 | T.J. Hockenson 1 yard Passing Completion from Jared Goff Jaquiski Tartt | 7-0 | 0.1 |
| DET | 4th | 1:56 | 1st | Goal | SF 1 | Jamaal Williams 1 yard Rushing TD | 41-23 | 6.1 |
| SF | 3rd | 1:24 | 3rd | 1 | SF 46 | Trey Lance -1 yard Rushing Attempt Jamie Collins | 38-17 | -0.1 |
| DET | 3rd | 6:36 | 4th | 1 | DET 34 | Jamaal Williams 6 yard Rushing Attempt Arden Key | 38-10 | 0.6 |
| DET | 3rd | 6:40 | 3rd | 1 | DET 34 | Jared Goff Incomplete Pass to Jason Cabinda | 38-10 | |
| DET | 1st | 0:12 | 4th | 1 | SF 17 | Tyrell Williams 7 yard Passing Completion from Jared Goff Jason Verrett | 7-0 | 0.7 |
| SF | 1st | 8:26 | 2nd | 1 | DET 39 | George Kittle 23 yard Passing Completion from Jimmy Garoppolo Tracy Walker, Will Harris | 0-0 | 2.3 |
| DET | 1st | 12:01 | 4th | 1 | SF 35 | Jamaal Williams -1 yard Rushing Attempt Jaquiski Tartt | 0-0 | -0.1 |
| DET | 4th | 1:07 | | | SF 2 | Quintez Cephus 2 Pt Conversion Passing from Jared Goff | 41-33 | 2 |
| DET | 4th | 1:53 | | | SF 2 | T.J. Hockenson 2 Pt Conversion Passing from Jared Goff | 41-25 | 2 |
| SF | 3rd | 4:23 | | | DET 35 | Ambry Thomas 19 yard Kick Return Attempt Godwin Igwebuike | 38-17 | |
| DET | 3rd | 4:23 | | | SF 15 | Austin Seibert XP | 38-17 | 1 |
| SF | 3rd | 7:54 | | | DET 15 | Robbie Gould XP | 38-10 | 1 |
| SF | 3rd | 15:00 | | | DET 35 | Ambry Thomas 16 yard Kick Return Attempt Anthony Pittman | 31-10 | |
| SF | 2nd | 1:10 | | | DET 15 | Robbie Gould XP | 31-10 | 1 |
| DET | 2nd | 0:03 | | | SF 35 | Godwin Igwebuike 1 yard Kick Return Attempt Samson Ebukam | 30-10 | |
| DET | 2nd | 2:25 | | | SF 35 | Godwin Igwebuike 19 yard Kick Return Attempt Dontae Johnson | 21-10 | |
| SF | 2nd | 2:25 | | | DET 15 | Robbie Gould XP | 21-10 | 1 |
| SF | 2nd | 6:13 | | | DET 35 | Ambry Thomas 19 yard Kick Return Attempt Anthony Pittman, Jason Cabinda | 14-10 | |
| SF | 2nd | 11:12 | | | DET 15 | Robbie Gould XP | 14-7 | 1 |
| SF | 2nd | 13:29 | | | DET 35 | Ambry Thomas 16 yard Kick Return Attempt Jerry Jacobs | 7-7 | |
| DET | 2nd | 13:29 | | | SF 15 | Austin Seibert XP | 7-7 | 1 |
| SF | 1st | 5:41 | | | SF 35 | Godwin Igwebuike Fumble recovered by Godwin Igwebuike Tavon Wilson | 7-0 | -1 |
| SF | 1st | 5:41 | | | DET 15 | Robbie Gould XP | 7-0 | 1 |
| DET | 1st | 15:00 | | | SF 35 | Godwin Igwebuike 27 yard Kick Return Attempt Samson Ebukam | 0-0 | |