Wilkins has recovered after being inactive in Week 7 with an illness.

EDGE Analysis

The running back was estimated as a full participant in Wednesday's walkthrough practice and is expected to be active in Week 8 versus the Titans. Wilkins is still unlikely to make any offensive impact as the fourth option behind Jonathan Taylor, Nyheim Hines and Marlon Mack.

Wilkins (illness) has been ruled out for Sunday's game at San Francisco.

EDGE Analysis

Wilkins has missed the past two games while battling the illness, and he'll be sidelined again for this weekend. The 27-year-old will need to return to practice in some capacity before having a chance to return to game action.

Wilkins (illness) wasn't spotted on the field for Wednesday's practice, Kevin Bowen of 107.5 The Fan Indianapolis reports.

EDGE Analysis

Wilkins hasn't practiced since Oct. 7 due to the illness, missing two games along the way. Unless he gets back on the field in some capacity Thursday and/or Friday, he'll likely find himself on the Colts' inactive list again Sunday in San Francisco.

Wilkins (illness) has been ruled out for Sunday's game against the Texans, Joel A. Erickson of The Indianapolis Star reports.

EDGE Analysis

Wilkins will try to feel better in time to play against the 49ers in Week 7. He's a distant fourth on the Colts' backfield depth chart behind Jonathan Taylor, Nyheim Hines and Marlon Mack, so Wilkins will need an injury or two in front of him to take on a meaningful role once he's healthy again.

Wilkins (illness) didn't participate at Wednesday's practice.

EDGE Analysis

Wilkins was inactive for Monday's loss to the Ravens due to an illness, and he still hasn't been cleared to practice. It's unclear when the 27-year-old is expected to retake the field.

Wilkins (illness) won't play Monday night against the Ravens, Stephen Holder of The Athletic reports.

EDGE Analysis

With Wilkins unavailable for Monday's contest, the Colts' Week 5 backfield is in line to be headed by the trio of Jonathan Taylor, Nyheim Hines (shoulder) and Marlon Mack.

Wilkins was a non-participant at Friday's practice due to an illness.

EDGE Analysis

Wilkins was a full participant at Thursday's practice, so he presumably began feeling under the weather after that time. More clarity on his status will be gained via Saturday's practice report.

Wilkins did not have a carry or target in Sunday's loss to Seattle. He played 15 snaps, all on special teams.

EDGE Analysis

Neither Wilkins nor Marlon Mack played a snap on offense, which shows that the coaching staff is set on giving Jonathan Taylor and Nyheim Hines large workloads. Both Wilkins and Mack may have little role in the offense unless Taylor or Hines gets hurt.

Wilkins had five carries for 20 yards and two receptions for two yards in Saturday's preseason win over Minnesota.

EDGE Analysis

Wilkins will likely have a reserve role and sits fourth on the running back depth chart, but he's been given larger opportunities at times by the coaching staff. Over his 15 regular-season appearances in 2020, Wilkins logged 84 carries for 308 yards and a touchdown while also securing 12 of 16 targets for 105 yards.

Wilkins (hamstring) returned to practice Friday, George Bremer of The Anderson Herald Bulletin reports.

EDGE Analysis

Wilkins had been held out of practice since Tuesday due to a minor hamstring injury, but he's now been given the green light to rejoin teammates on the field. The 2018 fifth-round pick handled a career-high 84 carries last season, though though his YPC dropped down to 3.7 after sitting at 5.6 and 6.0 in 2018 and 2019.