The Minnesota Vikings activated running back Alexander Mattison from the Reserve/COVID-19 list on Wednesday. Mattison is unvaccinated and was required to quarantine for 10 days, but he's now eligible to return for the Week 16 matchup against the Los Angeles Rams. The 23-year-old is one of the best fantasy football handcuffs behind Dalvin Cook. But he should remain on your benches this weekend with Cook healthy as the team's workhorse running back.