Flannigan-Fowles (knee) is inactive for Sunday night's contest against the Bills, Lindsey Pallares of the 49ers' official website reports.

EDGE Analysis

Flannigan-Fowles suffered a knee injury in Week 12 versus the Packers and he'll now be forced to miss at least one contest as a result. In his absence, Dee Winters stands to see an increase in workload at strong-side linebacker versus Buffalo.