Guerendo tweaked his groin Monday and won't practice this week, Cam Inman of The San Jose Mercury News reports.
EDGE Analysis
After missing training camp and most of the preseason with a hamstring injury, Guerendo returned for San Francisco's final exhibition and took 13 touches for 35 yards in a 24-24 tie with the Raiders. His depth chart standing seemingly improved despite all the missed time this summer, as long-time No. 2 running back Elijah Mitchell was placed on season-ending injured reserve due to a hamstring injury that will require surgery. Jordan Mason now figures to enter Week 1 as the No. 2 back behind Christian McCaffrey, leaving Guerendo to focus on kickoff returns for the time being. Shanahan said Guerendo could be back at practice as soon as next week, meaning the rookie isn't ruled out for a Week 1 matchup with the Jets on Monday Night Football.