Downs (ankle) remained sidelined for Wednesday's practice, Kevin Bowen of 107.5 The Fan Indianapolis reports.
EDGE Analysis
Downs, who suffered a high-ankle sprain Aug. 7, has two more chances to log practice reps ahead of Sunday's season opener against the Texans. If Downs ends up being unavailable for the contest, fellow wideouts Adonai Mitchell and Alec Pierce would be in store for added opportunities versus Houston behind No. 1 receiver Michael Pittman.