Coach Sean McDermott said Friday that Palmer (knee/ankle) won't play Sunday against the Panthers, Maddy Glab of the Bills' official site reports.

EDGE Analysis

With Palmer unavailable, look for Keon Coleman and Khalil Shakir to lead the Bills' Week 8 WR corps, while Curtis Samuel, Tyrell Shavers and Elijah Moore will be available to mix in. Palmer's next chance to see game action will arrive Sunday, Nov. 2 against the Chiefs.