James (quadriceps) didn't practice Wednesday, Daniel Popper of The Athletic reports.

EDGE Analysis

James missed the Chargers' Week 14 win over the Dolphins with the injury, and now his availability for Sunday's game against the Titans appears to be in jeopardy as well. If the star safety is forced to sit out Sunday, Alohi Gilman would likely draw another start next to Nasir Adderley.