Brown won't practice Wednesday, Joe Buscaglia of The Athletic reports.

EDGE Analysis

The Bills' official injury report will be released later Wednesday and will reveal whether Brown is managing the knee issue that has bothered him in past weeks or if he's slowed by a new injury. Despite playing starter's snaps over his last two outings, Brown has logged back-to-back quiet efforts, catching just one of his six targets for 21 yards in that span.