Aiyuk is dealing with what's being described as a slight hamstring issue, Nick Wagoner of ESPN.com reports.

EDGE Analysis

As a result, Aiyuk won't play in Sunday's preseason finale versus the Raiders. However, the 49ers' starting wideout is expected to be fine by next week, according to coach Kyle Shanahan. Assuming that's the case, Aiyuk's Week 1 status is not in any jeopardy.