Ihedigbo sustained an ankle injury during Sunday's loss to Pittsburgh, BuffaloBills.com reports.
EDGE Analysis
Ihedigbo did have six tackles before departing, though that's partly because everyone in the secondary was far too familiar with Pittsburgh's Le'Veon Bell as the game wore on. If Ihedigbo can't go this week against the Browns, the Bills will likely split his usual workload between Jonathan Meeks and Corey White.