Aiyuk (hamstring) didn't practice Wednesday, David Lombardi of The Athletic reports.

EDGE Analysis

Coach Kyle Shanahan expected as much as Aiyuk looks to put a mild left hamstring strain behind him. The rookie first-round pick has two more opportunities to prove his health before Sunday's contest against the Cardinals, but the 49ers' receiving corps could be less than expected if one or both of Aiyuk and Deebo Samuel (foot) sit out this weekend.