Herron's teammates LeSean McCoy and Karlos Williams are both healthy again coming out of the bye week.

EDGE Analysis

Herron had a window of opportunity when both players were down a few games ago, but didn't really do much with his 11 carries, averaging just 3.4 yards per. At best, he's now the No. 3 back with Williams ready to return from his concussion.

Herron carried two times for nine yards in Sunday's loss to the Jaguars in London. He also caught his only target for three yards.

EDGE Analysis

It looked like LeSean McCoy was going to be done for the day after he took a brutal blow on a costly fumble late in the game, but Shady returned and Herron stayed in his backup role. Even though he's passed Anthony Dixon in the pecking order, with a bye coming up and Karlos Williams likely to return from a concussion at some point, Herron's window for value in deep leagues may be closing.

Herron caught both of his targets for 17 yards in Sunday's loss to the Bengals and did not record a carry.

EDGE Analysis

LeSean McCoy took every single carry that went to a running back, so with Shady healthy and Karlos Williams (concussion) back at some point, Herron's role will remain quite minimal.

Herron picked up 28 yards on nine carries Sunday against the Titans, but was not targeted in the passing game.

EDGE Analysis

The newly acquired Herron led the Bills in carries, but failed to find much running room. This pedestrian performance doesn't bode well for Herron's chances of future production, especially with injured lead back LeSean McCoy (hamstring) possibly due back soon and Boobie Dixon on hand to split carries as it is.

Herron, picked up by the Bills on Tuesday, is already looking good in practices with his fresh legs and is hitting the hole better than any of the team's healthy backs, BuffaloBills.com reports. "I think Boom is going to...you know there's a good chance that he's going to be a part of the game plan," said offensive coordinator Greg Roman. "I really like what I see out of him, like what I hear out of him and he's picking things up pretty quickly."

EDGE Analysis

Herron knows this offensive system because it's the same one used by his former team, the Colts. While Anthony Dixon will get first crack at the Titans this week, don't be surprised if Herron gets at least a handful of carries, with the potential for more should he look significantly better than Dixon. Still, he's a dart this week until things better sort themselves.

Herron's teammates LeSean McCoy and Karlos Williams have both officially been ruled out for Sunday's game in Tennessee.

EDGE Analysis

Anthony Dixon will get first crack at the Titans and their 22nd-ranked run defense, however the folks running the Bills have made statements this week that they won't be afraid to use Herron. He's familiar with offensive coordinator Greg Roman's terminology and scheme and had some success at times last season with the Colts around their running game issues elsewhere.

Herron (shoulder) signed with the Bills on Tuesday, ESPN.com's Mike Rodak reports.

EDGE Analysis

With LeSean McCoy (hamstring) and Karlos Williams (concussion) both in danger of missing Sunday' game in Tennessee, Anthony Dixon may have to lead the Buffalo backfield. Herron has presumably recovered from the shoulder injury he dealt with earlier this season, and he could have an immediate role on passing downs. Herron doesn't have much of a ceiling, as Cierre Wood could also be involved in the offense, and the Buffalo running backs have only accounted for 20 targets this season.

The Colts have waived Herron (shoulder) from injured reserve, Kevin Bowen of Colts.com reports.

EDGE Analysis

The Colts came to an injury settlement with the running back and he'll be free to catch on with another team and play once at some point this season once his injury shoulder heals up.

Herron (shoulder) was placed on injured reserve Monday, Stephen Holder of the Indianapolis Star reports.

EDGE Analysis

Herron sustained a shoulder injury in the preseason finale, and after he was initially considered unlikely to play in Week 1, the Colts instead waived the running back with an injury designation over the weekend. Currently on IR, the potential exists for the two sides to reach an injury settlement, which would allow Herron to sign with another organization.

Herron (shoulder) has been waived/injured by the Colts, the Indianapolis Star reports.

EDGE Analysis

If Herron clears waivers, he'll revert to IR, but his injury is a hit to the team's backfield depth behind starter Frank Gore. With Herron no longer in the mix, Josh Robinson could ascend to the team's No. 2 RB slot once he is cleared to play. The Colts also currently roster Vick Ballard and Tyler Varga at the running back position.