Mayfield was limited at Wednesday's walkthrough due to a knee injury, Brianna Dix of the Buccaneers' official site reports.

EDGE Analysis

Mayfield was stymied by the Lions defense in Monday's 24-9 loss, completing 28 of 50 passes for 228 yards, one touchdown and one interception. He also didn't record a carry after being effective as a scrambler through the first six games of the campaign. Perhaps the knee issue was partly responsible, and he'll now have two chances to get back to full this week or else risk entering the weekend with a designation for Sunday's contest at New Orleans.

Mayfield completed 28 of 50 passes for 228 yards with a touchdown and an interception in the Buccaneers' 24-9 loss to the Lions on Monday night. He also committed a fumble recovered by Tampa Bay.

EDGE Analysis

Mayfield went into the game with both Mike Evans and Emeka Egbuka available despite their respective hamstring injuries, but he ended up losing the former to a shoulder injury -- which Rick Stroud of the Tampa Bay Times reports was subsequently diagnosed as a broken collarbone -- and a concussion in the first half. Mayfield had already been struggling to get the ball to Evans considering the pass on which he suffered the pair of injuries was his fourth target without a catch, and the veteran signal-caller displayed only modest improvement over the rest of the night even though the Lions were playing with an extremely short-handed secondary. Mayfield saw a two-game interception-less streak come to an end as well on a controversial play that originally appeared to be a Cade Otton reception, and it remains to be seen if he'll at least have Chris Godwin (fibula) at his disposal to help offset the loss of Evans in a Week 8 road matchup versus the Saints on Sunday.

Mayfield completed 17 of 23 pass attempts for 256 yards and two touchdowns while taking three carries for 14 yards in Sunday's 30-19 win over the 49ers.

EDGE Analysis

Mayfield produced a sterling 139.0 passer rating against a 49ers defense that was helpless after losing LB Fred Warner (ankle) early in the contest. The Buccaneers also suffered a key loss early on when WR Emeka Egbuka (hamstring) exited the game after recording just two receptions. This meant that Mayfield had to finish off the win sans his three top weapons, with Mike Evans (hamstring) and Chris Godwin (fibula) in street clothes Sunday. The 30-year-old Mayfield overcame expectations and produced his fifth multi-score game through six starts. With the Buccaneers visiting the Lions on Monday Night Football in Week 7, it will be important for fantasy managers to note which receivers Mayfield will have at his disposal before making roster decisions.

Mayfield completed 29 of 33 pass attempts for 379 yards and two touchdowns while rushing five times for 15 yards in Sunday's 38-35 win over the Seahawks.

EDGE Analysis

Mayfield flirted with perfection in a masterful performance that saw him miss just four pass attempts while committing zero turnovers. The 30-year-old was especially sharp in the clutch when he led a pair of five-play drives that took up a little over one minute of game clock to give Tampa Bay the 10 points needed to secure victory. The loss of star WR Mike Evans (hamstring) hasn't hampered Mayfield and the passing offense, as the signal-caller is averaging 334.0 passing yards with a pair of touchdowns in the two games sans Evans. Mayfield will look to build off of the momentum of his cleanest outing when the Buccaneers host the 49ers next Sunday.

Mayfield (knee/right biceps) doesn't have a designation for Sunday's game at Seattle, Brianna Dix of the Buccaneers' official site reports.

EDGE Analysis

After sitting out Wednesday's practice due to knee and right biceps injuries, Mayfield logged back-to-back full sessions to end Week 5 prep, clearing him to continue to lead Tampa Bay's offense Sunday. He'll be without the services of RB Bucky Irving (foot/shoulder) and WR Mike Evans (hamstring) this weekend, though, meaning the key skill-position players available to the quarterback are RBs Rachaad White and Sean Tucker, WRs Chris Godwin, Emeka Egbuka and Sterling Shepard and TE Cade Otton.

Mayfield (knee/right biceps) was a full practice participant Thursday.

EDGE Analysis

Mayfield sat out Wednesday's walkthrough due to knee and right biceps injuries, but his return to all activity one day later indicates the DNP was merely for maintenance purposes. He's been slinging it around this season, completing 83 of 139 passes (60 percent) for 904 yards, eight touchdowns and one interception through four games. The potential exists for both WR Mike Evans (hamstring) and RB Bucky Irving (foot/shoulder) to be sidelined Sunday at Seattle, so Mayfield's primary pass catchers Week 5 may be WRs Chris Godwin, Emeka Egbuka and Sterling Shepard, TE Cade Otton and RBs Rachaad White and Sean Tucker.

Mayfield (knee/biceps) was spotted practicing during the portion of Thursday's session that was open to the media, Greg Auman of Fox Sports reports.

EDGE Analysis

Mayfield sat out Wednesday's walk-through session due to knee and right biceps injuries, though his absence may have been more of a maintenance day than anything. His presence on the field Thursday is a good sign that Mayfield will be available to play this weekend in Seattle, though it won't be known until after practice concludes whether the quarterback was a limited or full participant. Assuming he's ultimately cleared in advance of Sunday's contest, Mayfield will be working behind a beat-up offensive line and could be without two key players in running back Bucky Irving (foot/shoulder) and wideout Mike Evans (hamstring), neither of whom has been able to practice so far this week.

Mayfield didn't take part in Wednesday's walkthrough due to knee and right biceps injuries, Jenna Laine of ESPN.com reports.

EDGE Analysis

Mayfield was among a number of key skill-position players that were held out of drills to begin Week 5 prep -- the others being RB Bucky Irving (foot/shoulder) and WRs Mike Evans (hamstring) and Sterling Shepard (foot). Meanwhile, WR Chris Godwin (ankle) emerged from his first game action since last season as a full participant Wednesday. Mayfield was limited in all three sessions last week due to a right biceps injury, so the addition of the knee issue indicates he's a bit more banged-up this time around. He'll have two more chances to practice this week to prove his health ahead of Sunday's contest at Seattle.

Mayfield completed 22 of 40 passes for 289 yards with two touchdowns and one interception while adding two rushes for 13 yards in the Buccaneers' 31-25 loss to the Eagles on Sunday. He also fumbled once but recovered.

EDGE Analysis

Mayfield had only managed to throw in Friday's practice this past week due to a biceps issue, and the combination of that injury and a sticky Eagles secondary led to the veteran signal-caller's second-lowest yardage completion percentage of the season (55.0 percent). Ironically, he also mustered his best passing yardage total yet in 2025, thanks in large part to 77- and 72-yard touchdown passes to Emeka Egbuka and Bucky Irving, respectively. Mayfield also had a pair of gutsy runs, and considering he was playing without Mike Evans (hamstring) and Chris Godwin was making his season debut, his numbers have to be considered encouraging. Mayfield will aim to get the Bucs right back in the win column during a tough Week 5 road matchup against the Seahawks next Sunday afternoon.

Mayfield (right biceps) is listed as active Sunday against the Eagles.

EDGE Analysis

Mayfield operated with a cap on his reps during Week 4 prep due to a right biceps injury and wasn't seen throwing passes until Friday's practice. Despite entering the weekend as questionable, he'll lead the Buccaneers offense as he normally does Sunday, with Chris Godwin (foot) swapping in for an absent Mike Evans (hamstring) at wide receiver. Godwin is making his season debut after completing his recovery from the dislocated left ankle that he suffered Week 7 of the 2024 campaign, so he may not be running on all cylinders for at least a few games. In any case, Mayfield's top available skill-position talents will be RB Bucky Irving, WRs Godwin, Emeka Egbuka and Sterling Shepard and TE Cade Otton.