Mattison (ankle) was listed as a non-participant on Tuesday's practice estimate.

EDGE Analysis

Mattison racked up 66 yards on 10 carries in Sunday's 3-0 win over the Raiders before exiting with a right low-ankle sprain. His estimated non-participation on Tuesday's report isn't a great sign for his early prospects of playing Saturday against the Bengals, but more clarity on Mattison's status will be gained as the week progresses. Ty Chandler would likely be in line to handle a lead role out of the Minnesota backfield if Mattison is unable to play this weekend.

Coach Kevin O'Connell said after Sunday's 3-0 win over the Raiders that Mattison is dealing with a sprained ankle, Ben Goessling of the Star Tribune reports.

EDGE Analysis

Mattison exited in the second half after racking up 66 rushing yards on 10 carries. His return timetable will hinge on the severity and location of the sprain, as low-ankle sprains often take no more than two weeks to come back from, while high-ankle sprains usually result in multi-week absences. Ty Chandler would be in line to handle the majority of snaps in Minnesota's backfield if Mattison misses additional time.

Mattison sustained an ankle injury during Sunday's game at Las Vegas, Alec Lewis of The Athletic reports.

EDGE Analysis

It's been a rough injury day for the Vikings, who have lost top wide receiver Justin Jefferson (chest), starting right tackle Brian O'Neill (ankle) and now their No. 1 running back. Mattison got injured on the team's first offensive play of the second half, and if he's unable to reenter the contest, he'll end Week 14 with 10 carries for 66 yards. Ty Chandler took over Minnesota's backfield after Mattison's departure.

Mattison rushed 10 times for 52 yards and secured both targets for 11 yards in the Vikings' 12-10 loss to the Bears on Monday night. He also fumbled once but recovered.

EDGE Analysis

Mattison led the Vikings in rushing yards and averaged over 5.0 yards per carry for just the second time this season with the help of a 21-yard run. The veteran back also saw two targets for the fourth straight contest, and his rushing yardage total qualified as his second highest since Week 4. Mattison notably outpaced Ty Chandler by six carries, sending the former into the Week 13 bye in control of the No. 1 running back role before a favorable Week 14 road matchup versus the Raiders.

Mattison rushed 18 times for 81 yards and brought in his only target for minus-1 yard in the Vikings' 21-20 loss to the Broncos on Sunday night. He also lost a fumble.

EDGE Analysis

Mattison got off to a hot start before his efficiency waned some late, but he still finished with his highest rushing yardage total since Week 4. The fifth-year pro's fumble was also costly, as it came on the Broncos' 35-yard line and led to a Denver field goal. On the brighter side, Mattison made a remarkably quick recovery from his Week 10 concussion to suit up Sunday night and outpaced backfield mate Ty Chandler by eight carries, seemingly keeping his hold on the No. 1 running back job secure heading into a Week 12 home matchup against the Bears on Monday night, Nov. 27.

Mattison (concussion) is active for Sunday's contest at Denver.

EDGE Analysis

Mattison left last Sunday's win against the Saints in the third quarter due to a concussion, but he made quick progress through the protocol for head injuries, including a full practice Friday and a declaration from coach Kevin O'Connell that same day that the Vikings expected the running back to gain clearance soon from an independent neurologist, per Ben Goessling of the Minneapolis Star Tribune. With his status confirmed for Sunday Night Football, Mattison now may have to contend with fellow running back Ty Chandler for work after the latter had 15 carries for 45 yards and one touchdown Week 10.

Mattison (concussion) is expected to play Sunday night against the Broncos, Ian Rapoport of NFL Network reports.

EDGE Analysis

Mattison exited Week 10 and spent much of the past week in the league's concussion protocol, but he was able to practice fully Friday after a limited session Thursday. With Mattison likely to be active, Ty Chandler will handle change-of-pace duties alongside him, leaving Kene Nwangwu mainly handling special teams work.

Mattison (concussion) is listed as questionable for Sunday's game in Denver.

EDGE Analysis

Mattison departed the Vikings' Week 10 win against the Saints due to a concussion, and after sitting out Wednesday's session and returning as a limited practice participant one day later, he has a chance to miss no games as a result. Coach Kevin O'Connell even told Ben Goessling of the Minneapolis Star Tribune that Mattison likely will gain clearance from an independent neurologist Friday, but that has yet to come to pass. Assuming he's able to suit up this weekend, Mattison should be good to approach the range of his typical 15.4 touches per game.

Mattison (concussion) practiced in a limited capacity Thursday.

EDGE Analysis

Mattison was estimated as a non-participant on Wednesday's practice report due to the concussion that knocked him out of this past Sunday's win against the Saints. One day later, he displayed some progress through the protocol for head injuries with a capped session. Mattison thus has only one more chance to get back to all activity this week, and he'll have the added step of needing to gain clearance from an independent neurologist in order to play Sunday at Denver. If Mattison is sidelined this weekend, Ty Chandler, Kene Nwangwu and potentially practice-squad member Myles Gaskin will be the beneficiaries out of the Vikings backfield.

Mattison (concussion) was listed as a non-participant on Wednesday's practice estimate.

EDGE Analysis

Mattison departed this past Sunday's win against the Saints with a head injury and eventually was confirmed to be in the concussion protocol Monday. With no on-field work to speak of to begin Week 11 prep, he doesn't appear to be in a great spot ahead of Sunday's game at Denver. If Mattison is unable to gain clearance from an independent neurologist by Saturday, the Vikings may be forced to use the combination of Ty Chandler and Kene Nwangwu out of their backfield this weekend.