Mikolas will draw the start for Thursday's Opening Day matchup with the Blue Jays, John Denton of MLB.com reports.

EDGE Analysis

Mikolas will replace Adam Wainwright (groin) as the first pitcher to toe the rubber for St. Louis in 2023. The Opening Day start will be the second of his career, and the 34-year-old will look to build off a very successful 2022 campaign in which he posted a 3.29 ERA and 1.03 WHIP over 202.1 innings in 33 starts for the Cardinals.