Mayers will start Wednesday's game against the Padres, Rhett Bollinger of MLB.com reports.

EDGE Analysis

Manager Joe Maddon will employ a bullpen game in the series finale at San Diego, and Mayers will be the first reliever to take the mound. He has a 4.16 ERA, 1.34 WHIP and 76:20 K:BB across 62.2 innings this season and figures to pitch one or two frames Wednesday.