Santana has been diagnosed with a Grade 2 shoulder sprain and will likely miss the rest of the season, MLB.com's Rhett Bollinger reports.

EDGE Analysis

Santana will not require surgery on his shoulder, but his recovery timetable is 4-to-6 weeks, so he presumably will not play again in 2016. He should be back at 100 percent well in advance of spring training, when he will try to lock down a spot on the Twins' Opening Day roster.