Ryan had to be removed from Wednesday's Grapefruit League game with an apparent knee injury, David Lennon of Newsday reports. Ryan had to be helped down the dugout stairs, so it appears that it could be more than just a minor setback. With Didi Gregorius nursing his own injury, Ryan was in line to fill in at shortstop if Gregorius wasn't back in time for Opening Day. Nick Noonan replaced Ryan in the spring game and could take his roster spot if he's forced to miss extended time, but more news regarding the extent of the injury should become available after Wednesday's game.