Ramirez left Tuesday's game against the Cubs with an apparent hamstring injury, the Union-Tribune's Dennis Lin reports.

EDGE Analysis

The Padres can't buy a break, as Adam Rosales and Jose Pirela would be the only healthy middle infielders left on the 25-man roster, and both players are better suited for a bench role. Rosales replaced Ramirez as a pinch-runner in the fifth inning Tuesday. Ramirez's status will be updated when the team releases more details regarding the injury.