Ortiz exited Sunday's game in the fifth inning with a tight right calf, Pete Abraham of The Boston Globe reports.

EDGE Analysis

It's unclear exactly what might have caused the calf tightness, but it will force him to miss the remainder of Sunday's contest at a minimum. Allen Craig will bat for him the rest of the way, and the team will likely provide an update on Ortiz's status at some point in the near future.