Nelson gave up four runs on eight hits and two walks with three strikeouts in 6.2 innings in Wednesday's loss to the White Sox. Nelson gave up a sac fly to Melky Cabrera in the first before cleanup hitter Avisail Garcia and Adam LaRoche hit back-to-back solo shots to center with two outs. After giving up three runs in the first, Nelson settled down and didn't allowed another White Sox run until the seventh when Gordon Beckham scored on an infield single by Emilio Bonifacio. Nelson's next start will be at Detroit on Tuesday.