Matt Cain took a typically hard-luck loss on Wednesday, allowing two runs on four hits and three walks in seven innings of San Francisco's 3-1 setback against the Padres at home. Now 11-10, Cain has received just 27 runs of support in his 10 losses this season. He'll bring a 2.84 ERA, 1.06 WHIP and 164/53 K/BB ratio into his Tuesday rematch with the Padres in San Diego.