Harrison exited Saturday's rain-postponed game against the Cubs in the 11th inning with a left ankle injury, Rob Biertempfel of the Pittsburgh Tribune-Review reports. It's not clear what type of setback Harrison suffered Saturday, but he has apparently been dealing with lingering soreness in his ankle for a few weeks. He is unlikely to play in the Pirates' scheduled game Saturday evening, but the Pirates have yet to provide an official update on his status.