Donaldson left Wednesday's game against Seattle after the first inning due to a tight right calf muscle, Phil Miller of the Minneapolis Star Tribune reports.

EDGE Analysis

Donaldson appeared to grimace after rounding first base after a hit. He hurt his leg rounding first base on Opening Day and landed on the injured list. The Twins say his removal this time was as a precaution, but it's concerning given his history of calf injuries.