Danny Duffy allowed six runs -- five earned -- over four innings Wednesday in a loss to the Astros. Duffy has now been lit up in back-to-back outings since carrying a perfect game into the seventh inning May 17 against the Orioles. The 25-year-old lefty still has a solid 3.57 ERA and 1.25 WHIP on the year, but he faces a tough matchup next week in St. Louis.