Cole holds a career 7-1 mark with a 2.55 ERA and 1.10 WHIP in 56.1 innings against the Cubs.

EDGE Analysis

He's gone 2-1 with a 13:1 K:BB ratio and 1.50 ERA in 12 innings versus Chicago with umpire Jeff Nelson -- who will call balls and strikes Wednesday -- behind the plate. By contrast, mound opponent Jake Arrieta has never pitched with Nelson serving as the home plate umpire. Nelson calls more strikes on pitches outside the strike zone and fewer balls inside the zone than does the average major league umpire. As a result, look for an even tighter pitching matchup.