Little was removed from Friday's game against the Cardinals due to shoulder discomfort, Maddie Lee of the Chicago Sun-Times reports.

EDGE Analysis

Little was only able to throw four pitches and didn't retire a batter before his shoulder forced him to make an early exit. The Cubs haven't offered any information regarding the seriousness of the southpaw's injury, and there's no telling whether he'll be available to pitch again before the All-Star break.